This document discusses compassion fatigue, which refers to the negative effects helping professionals can experience from exposure to traumatic stories and events through their work. It is comprised of secondary traumatic stress, burnout, and lack of compassion satisfaction. The document provides examples of codes of ethics from various professions addressing self-care. Risk and protective factors are discussed, as well as implications for individuals, clinical practice, and organizations. Suggestions are made for addressing compassion fatigue through education, support, and advocacy.