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Seeley’s
ESSENTIALS OF
Anatomy &
Physiology
Tenth Edition
Cinnamon Vanputte
Jennifer Regan
Andrew Russo
See separate PowerPoint slides for all figures and tables
pre-inserted into PowerPoint without notes.
© 2019 McGraw-Hill Education. All rights reserved. Authorized only for instructor use in the classroom. No reproduction or further distribution permitted without the prior written consent of McGraw-Hill Education.
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Chapter 7
Muscular System
Lecture Outline
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Types of Muscles
Skeletal
attached to bones
striated
voluntarily controlled
Cardiac
located in the heart
striated
involuntarily controlled
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Types of Muscles
Smooth
Located in blood vessels, hollow
organs
Non-striated
involuntarily controlled
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Comparison of Skeletal, Cardiac, and Smooth Muscles
Characteristics Skeletal Cardiac Smooth
Body location Attached to bones
or, for some facial
muscles to skin
Walls of the heart Mostly in walls
of hollow
visceral organs
Cell shape and
appearance
Single, very long,
cylindrical, multi-
nucleate cells with
very obvious
striations
Branching chains of
cells; uninucleate,
striations;
intercalated discs
Single, fusiform,
uninucleate, no
striations
Connective tissue
components
Epimysium,
perimysium, and
endomysium
Endomysium
attached to the
fibrous skeleton of
the heart
Endomysium
Regulation of
contraction
Voluntary, via
nervous system
control
Involuntary; the
heart has pacemaker;
nervous system
control; hormone
Involuntary;
nervous system
controls;
hormones,
chemicals
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Characteristics Skeletal Cardiac Smooth
Speed of
Contraction
Slow to fast slow Very slow
Rhythmic
contraction
No Yes Yes, in some
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The Muscular System
Functions
 Movement
 Maintain posture
 Respiration
 Production of body heat
 Communication
 Heart beat
 Contraction of organs and
vessels
Figure 7.1
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Properties of Muscles
Contractility
 the ability of muscle to shorten forcefully,
or contract
Excitability
 the capacity of muscle to respond to a
stimulus
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Properties of Muscles
Extensibility
 ability to be stretched beyond it normal
resting length and still be able to contract
Elasticity
 ability of the muscle to recoil to its original
resting length after it has been stretched
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Skeletal Muscle Structure1
 Skeletal muscle, or striated muscle, with its
associated connective tissue, constitutes
approximately 40% of body weight.
 Skeletal muscle is so named because they are
attached to the skeletal system.
 Some skeletal muscles attach to the skin or
connective tissue sheets.
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Skeletal Muscle Structure2
 Skeletal muscle is also called striated muscle
because transverse bands, or striations.
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Connective Tissue Coverings
 Epimysium a connective tissue sheath that
surround each skeletal muscle
 A skeletal muscle is subdivided into groups of
muscle cells, termed fascicles.
 Perimysium -surround the fascicle.
 Endomysium - surround each skeletal muscle
cell (fiber)
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Muscle Fiber Structure1
 a single cylindrical cell, with several nuclei
located at its periphery.
 It range in length 1 cm to 30 cm and are
generally 0.15 mm in diameter.
 Skeletal muscle fibers contain several nuclei
that are located at the periphery of the fiber.
 The sarcolemma (cell membrane) has many
tubelike inward folds, called transverse
tubules, or T tubules.
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Muscle Fiber Structure2
 T tubules occur at regular intervals along the
muscle fiber and extend into the center of the
muscle fiber.
 The T tubules are associated with enlarged
portions of the smooth endoplasmic reticulum
called the sarcoplasmic reticulum.
 The enlarged portions are called terminal
cisternae.
 T tubules connect the sarcolemma to the terminal
cisternae to form a muscle triad.
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Muscle Fiber Structure3
 Sarcoplasm it the cytoplasm of a muscle fiber
which contains many bundles of protein
filaments.
 Myofibrils are bundles of protein filaments.
 Myofibrils consist of the myofilaments, actin
and myosin.
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Figure 8.1
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Structure of Skeletal Muscle
Figure 7.2
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Sarcomere1
 the basic structural and functional unit of a
skeletal muscle capable of contracting.
 Z Disks - form a network of protein fibers
that serve as an anchor for actin
myofilaments and separate one sarcomere
from the next.
 A sarcomere extends from one Z disk to the
next Z disk.
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The Sarcomere2
 The organization of actin and myosin
myofilaments gives skeletal muscle its
striated appearance and gives it the ability
to contract.
 The myofilaments slide past each other,
causing the sarcomeres to shorten.
 Each sarcomere consists of two light-staining
bands separated by a dark-staining band.
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Figure 8.2c
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The Sarcomere3
 I bands -light bands, consist only of actin
myofilaments that extends toward the
center of the sarcomere to the ends of the
myosin myofilaments.
 A bands -dark staining bands that extend the
length of the myosin myofilaments.
 Actin and myosin myofilaments overlap for
some distance on both ends of the A band
that causes the contraction.

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Figure 8.2c
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The Sarcomere4
 Actin myofilaments are made up of three
components: Actin, Troponin, and Tropomyosin.
 Troponin -molecules have binding sites for Ca2
+
 Tropomyosin - filaments block the myosin
myofilament binding sites on the actin
myofilaments.
 Myosin myofilaments, or thick myofilaments,
resemble bundles of tiny golf clubs.
 Myosin heads have ATP binding sites, ATPase and
attachment spots for actin.
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Figure 8.3a
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Figure 8.3b
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Sliding Filament Mechanism
During contraction myosin heads bind actin
sites
Pull and slide actin molecules (and Z-discs)
toward H-zone
I-bands and H-zones narrow
Sliding generates force and shortens
sarcomeres.
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Figure 8.4
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Skeletal Muscle Fiber
Figure 7.3
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Excitability of Muscle Fibers
 Muscle cells (fibers) have a resting membrane
potential, but can also perform action
potentials.
Resting Membrane Potential
 the inside of the membrane is negatively charged and
the outside of the membrane is positively charged.
Action potentials
 due to the membrane having gated channels.
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Resting Membrane Potential1
The resting membrane potential exists because of:
 The concentration of K+ being higher on the inside of
the cell membrane and the concentration of Na+ being
higher on the outside
 The presence of many negatively charged molecules,
such as proteins, inside the cell that are too large to
exit the cell
 The presence of leak protein channels in the
membrane that are more permeable to K+ than it is to
Na+
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Resting Membrane Potential2
 Na+ tends to diffuse into the cell and K+ tends
to diffuse out.
 In order to maintain the resting membrane
potential, the sodium-potassium pump
recreates the Na+ and K+ ion gradient by
pumping Na+ out of the cell and K+ into the
cell.
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Resting Membrane Potential3
Figure 7.4 (1)
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Action Potential1
 Resting membrane potential must be changed
to an action potential.
 Changes in the resting membrane potential
occur when gated cell membrane channels
open.
 In a skeletal muscle fiber, a nerve impulse
triggers gated Na+ channels to open and Na+
diffuses into the cell down its concentration
gradient and toward the negative charges
inside the cell.
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Action Potential2
 The entry of Na+ causes the inside of the cell
membrane to become more positive than when
the cell is at resting membrane potential.
 This increase in positive charge inside the cell
membrane is called DEPOLARIZATION.
 If the depolarization changes the membrane
potential to a value called threshold, an action
potential is triggered.
 An action potential is a rapid change in charge
across the cell membrane.
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Action Potential3
 Depolarization during the action potential is
when the inside of the cell membrane becomes
more positively charged than the outside of the
cell membrane.
 Near the end of depolarization, the positive
charge causes gated Na+ channels to close and
gated K+ channels to open.
 Opening of gated K+ channels starts
repolarization of the cell membrane.
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Action Potential4
 Repolarization is due to the exit of K+ from
the cell.
 The outward diffusion of K+ returns the cell
to its resting membrane conditions and the
action potential ends.
 In a muscle fiber, an action potential results
in muscle contraction.
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Depolarization
 change in charges
inside becomes more + and outside more –
 Na+ channels open
Figure 7.4 (2)
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Repolarization
 Na+ channels close
 change back to resting potential
Figure 7.4 (3)
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Ion Channels and Action Potentials
Figure 7.4
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Nerve Supply & Muscle Fiber
Stimulation1
 Motor neuron - a nerve cell stimulates muscle
cells.
 Neuromuscular junction-a synapse where a the
fiber of a nerve connects with a muscle fiber.
 Synapse refers to the cell-to-cell junction
between a nerve cell and either another nerve
cell or an effector cell.
 Motor unit -a group of muscle fibers that a
motor neuron stimulates.
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Nerve Supply2
 Presynaptic terminal is the end of a neuron cell
axon fiber.
 Synaptic cleft is the space between the
presynaptic terminal and postsynaptic
membrane.
 Postsynaptic membrane is the muscle fiber
membrane (sarcolemma).
 Synaptic vesicle is a vesicle in the presynaptic
terminal that stores and releases
neurotransmitter chemicals.
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Nerve Supply3
 Neurotransmitters - are chemicals that
stimulate or inhibit postsynaptic cells.
 Acetylcholine - the neurotransmitter that
stimulates skeletal muscles.
 Acetylcholinesterase- an enzyme that breaks
down the acetylcholine to prevent
overstimulation of muscle fiber.
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Neuromuscular Junction
Figure 7.5
(b) ©Ed Reschke/Photolibrary/Getty Images
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Muscle Contraction1
1. An action potential travels down motor
neuron to presynaptic terminal causing Ca2+
channels to open.
2. Ca2+ causes synaptic vesicles to release
acetylcholine into synaptic cleft.
3. Acetylcholine binds to receptor sites on Na+
channels, Na+ channels open, and Na+ rushes
into postsynaptic terminal (depolarization).
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Function of the
Neuromuscular Junction
Figure 7.6
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Muscle Contraction2
4. Na+ causes sarcolemma and t-tubules to
increase the permeability of sarcoplasmic
reticulum which releases stored calcium.
5. Ca2+ binds to troponin which is attached to
actin.
6. Ca2+ binding to troponin causes tropomyosin
to move exposing attachment sites for myosin.
7. Myosin heads bind to actin.
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Muscle Contraction3
8. ATP is released from myosin heads and
heads bend toward center of sarcomere.
9. Bending forces actin to slide over myosin.
10. Acetylcholinesterase (enzyme breaks down
acetylcholine) is released, Na+ channels
close, and muscle contraction stops.
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Skeletal Muscle Excitation1
Figure 7.8 (1)
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Skeletal Muscle Excitation2
Figure 7.8 (2,3)
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Skeletal Muscle Excitation3
Figure 7.8 (4)
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Skeletal Muscle Excitation4
Figure 7.8 (5,6)
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Skeletal Muscle Excitation5
Figure 7.8 (6,7,8)
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Skeletal Muscle Excitation6
Figure 7.8 (9)
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Muscle Twitch1
 is a single contraction of a muscle fiber in
response to a stimulus.
 has three phases: latent phase, contraction
phase, and relaxation phase.
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Muscle Twitch1
Latent phase
 the time between the application of a stimulus
and the beginning of contraction.
Contraction phase
 the time during which the muscle contracts and
the
Relaxation phase
 is the time during which the muscle relaxes.
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Muscle Twitch2
Figure 7.10
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Summation and Recruitment
Summation- the individual muscles contract
more forcefully.
Tetanus is a sustained contraction that occurs
when the frequency of stimulation is so rapid
that no relaxation occurs.
Recruitment is the stimulation of several motor
units which increases the total number of muscle
fibers contracting.
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Multiple-Wave Summation
Figure 7.11
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Skeletal Muscle Fiber Types1
Slow twitch fibers
• contract slowly
• fatigue slowly
• have a considerable amount of myoglobin
• use aerobic respiration
• are dark in color
• used by long distance runners
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Skeletal Muscle Fiber Types2
Fast twitch fibers
• contract quickly
• fatigue quickly
• use anaerobic respiration
• energy from glycogen
• light color
• used by sprinters
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Energy Requirements
for Muscle Contractions
1. Aerobic production of ATP during most
exercise and normal conditions.
2. Anaerobic production of ATP during
intensive short-term work
3. Conversion of a molecule called creatine
phosphate to ATP
4. Conversion of two ADP to one ATP and one
AMP (adenosine monophosphate) during
heavy exercise
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ATP Production in Resting & Exercise
Muscle
REST
 1. ATP is produced by aerobic respiration
 2. Small amounts of ATP are used by muscle
contractions that maintain muscle tone
 3. Excess ATP is used to produced creatine
phosphate
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EXERCISE
4. As exercise begins, ATP already in the muscle cells is
used first, but during moderate exercise, aerobic
respiration provides most of the ATP necessary for
muscle contraction.
5. During times of extreme exercise, anaerobic
respiration provides small amount of ATP that can
sustain muscle contraction for brief periods.
6. Energy store in creatine phosphate can also be used
to produce ATP.
7. Throughout the time of exercise, ATP from all of
these sources (4-6) provides energy for active muscle
contraction.
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Muscle Fatigue1
 is a temporary state of reduced work
capacity.
 Without fatigue, muscle fibers would be
worked to the point of structural damage to
them and their supportive tissues.
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Mechanisms of Fatigue
 Acidosis and ATP depletion due to increased ATP
consumption or a decreased ATP production
 Oxidative stress- buildup of excess reactive oxygen
species (ROS; free radicals)
 Local inflammatory reactions
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Types of Contractions1
Isometric contraction
 has an increase in muscle tension, but no
change in length.
Isotonic contraction
 has a change in muscle length with no
change in tension.
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Types of Contractions2
Concentric contractions
 are isotonic contractions in which muscle
tension increases as the muscle shortens.
Eccentric contractions
 are isotonic contractions in which tension is
maintained in a muscle, but the opposing
resistance causes the muscle to lengthen.
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ISOTONIC EXERCISE
 There is a change in
muscle length, no
change in tension.
ISOMETRIC EXERCISE
 increase in muscle
tension, but no change
in length.
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Muscle Tone
 is the constant tension produced by body
muscles over long periods of time.
 responsible for keeping the back and legs
straight, the head in an upright position, and the
abdomen from bulging.
Disturbance in muscle tone
 Atrophy
 Flaccidity
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Smooth Muscle
 are non-striated small, spindle-shaped muscle
cells, usually with one nucleus per cell.
 Contain less actin and the myofilaments are
not organized into sarcomeres.
 The cells comprise organs controlled
involuntarily, except the heart.
 Neurotransmitter substances, hormones, and
other substances can stimulate smooth
muscle.
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Cardiac Muscle1
 are long, striated, and branching, with usually
only one nucleus per cell.
 is striated as a result of the sarcomere
arrangement
 contraction is autorhythmic.
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Cardiac Muscle
 muscle cells are connected to one another by
specialized structures that include
desmosomes and gap junctions called
intercalated disks.
 Cardiac muscle cells function as a single unit
in that action potential in one cardiac muscle
cell can stimulate action potentials in adjacent
cells causing to contract all together.
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Arrangement of Fascicles
Circular
 arranged in concentric rings or in circle
around the opening.
 Acts as sphincters to open and close the
opening
 Ex: orbicularis oris, orbicularis oculi
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Arrangement of Fascicles
Convergent
 fascicles converge toward a single
insertion tendon
 such muscle is triangular or fan-shaped.
 Ex: pectoralis major and minor
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Arrangement of Fascicles
Parallel
 the length of the fascicles run parallel to
one another to the long axis of the
muscle.
 Ex: trapezium, quadrate, rhomboidal
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Pennate
 Fascicles originate from a tendon that
runs the length of the entire muscle.
 Unipennate - fascicles on only one side of
the tendon. (Palmar interosseus)
 Bipennate- fascicles on both sides of the
tendon. (Rectus femoris)
 Multipennate- fascicles arranged at many
places around the central tendon (deltoid)
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Fusiform
 fascicles lie parallel to long axis of
muscle
 Ex: biceps brachii, triceps brachii
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Skeletal Muscles1
Figure 7.14a
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Skeletal Muscles2
Figure 7.14b
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Skeletal Muscle Anatomy
Tendon - connects skeletal muscle to bone.
Aponeuroses- are broad, sheetlike tendons.
Retinaculum- is a band of connective tissue
that holds down the tendons at each wrist and
ankle.
Origin – the most stationary, fixed, end of a
muscle.
Insertion -is the end of the muscle attached to
the bone undergoing the greatest movement.
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Skeletal Muscle Anatomy2
Belly
 the part of the muscle between the origin and
the insertion
Agonists
 a single or group of muscles working together.
Antagonists
 a muscle or group of muscles that oppose
muscle actions.
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Synergist
 members of a group of muscles working
together to produced movement
 Brachii and brachialis
 Deltoid, biceps brachii, and pectoralis major
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Muscle Attachment
Figure 7.13
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Prime Mover
 one muscle plays the major role to
accomplish the desired movement.
 Ex: Brachialis is the prime mover in flexing the
elbow
FIXATORS
 Are muscles that hold one bone in place
 stabilize origin of prime mover
 Scapular muscles acts as a fixator to hold the
scapula in place.
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Nomenclature1
Muscles are named according to:
1. Location – a pectoralis muscle is located in
the chest.
2. Size – the size could be large or small, short or
long.
3. Shape - the shape could be triangular,
quadrate, rectangular, or round.
4. Orientation of fascicles – fascicles could run
straight (rectus) or at an angle (oblique).
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Nomenclature2
5. Origin and insertion. The sternocleidomastoid
has its origin on the sternum and clavicle and
its insertion on the mastoid process of the
temporal bone.
6. Number of heads. A biceps muscle has two
heads (origins), and a triceps muscle has
three heads (origins).
7. Function. Abductors and adductors are the
muscles that cause abduction and adduction
movements.
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Figure 8-13a
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Figure 8-13b
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Muscles of the Head and Neck
 Facial muscles,
 Mastication or chewing tongue
 Swallowing muscles
 Eyes muscles
 head and neck muscles
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Figure 8.14
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Facial Muscles
BUCCINATOR
 Wall of the cheeks
 flattens the cheek (as in whistling or blowing
a trumpet)
 “Kissing Muscle or Trumpeter’s muscle
 Compresses cheek to hold food teeth
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Depressor anguli oris
 Lower corners of mouth/depresses the corner
of mouth
Levator Labii superioris
 Elevates one side of the upper lip
OccipitoFrontalis
 Moves scalp, raises eyebrows, and to wrinkle
your forehead
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Orbicularis oris
 closes the mouth and protrudes the lips,
 the “kissing” muscle
Orbicularis oculi
 close the eyes, squint, blink, and wink.
Zygomaticus
 the “smiling” muscle
 elevate the upper lip and corner of the
mouth.
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Muscles of Facial Expression
and Mastication
Figure 7.16
©McGraw-Hill Education/ Christine Eckel
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CHEWING MUSCLES
1. Masseter - closes the jaw by elevating and
pushing the mandible anteriorly
2. Temporalis -elevates and draws mandible
posteriorly.
3. Ptergoid
1. Lateral- pushes the mandible anteriorly and
depresses mandible, close the jaw
2. Medial- pushes the mandible anteriorly and
elevates mandible; closes the jaw
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Tongue and Swallowing Muscles
Tongue Muscles
 Intrinsic- change the shape of the tongue
 Extrinsic- moves the tongue
Hyoid Muscles
Suprahyoid (geniohyoid, stylohyoid, hyoglossus)
 elevates or stabilized hyoid
Infrahyoid- depresses or stabilizes hyoid
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Tongue and Swallowing Muscles
Figure 7.17
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Deep Neck Muscles
1. Neck Flexors
 originate on the anterior side of the vertebra
which flex the head and neck
2. Neck Extensor
 originate on the posterior side of the vertebra
that extend the head and neck
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Sternocleidomastoid
 Individually rotate the head; together it flex
the neck
Platysma
 pull the corners of the mouth inferiorly
Trapezius
 Extends and laterally flexes the neck
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Figure 8-13b
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Figure 8.14
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Trunk Muscles
 Vertebral column,
 Thorax,
 Abdominal wall and
 Pelvic floor.
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Trunk Muscles
Muscles of the Vertebral Column
Erector Spinae
 Extends vertebral column & maintain
posture.
 Divides in 3 column; Iliocostalis,
longissimus, Spinalis.
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Deep Neck and Back Muscles
Figure 7.18
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Deep Back Muscles
 Located between spinous and transverse
processes adjacent to vertebra
 Responsible for movement of vertebral
column including extension, lateral flexion
and rotation
 torn or stretched od these muscles cause
sprain and strain.
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Thoracic Muscles
Scalenes- elevates the ribs, during
inspiration
External intercostals- elevate ribs for
inspiration
Internal intercostals- depress ribs during
forced expiration
Diaphragm- moves during quiet breathing
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Muscles of the Thorax
Figure 7.19
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Abdominal Wall Muscles1
Rectus abdominis
 center of abdomen
 compresses abdomen
External abdominal oblique
 sides of abdomen
 compresses abdomen
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Abdominal Wall Muscles2
Internal abdominal oblique
 compresses abdomen
Transverse abdominis
 compresses abdomen
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Muscles of the Anterior Abdominal Wall
Figure 7.20
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Pelvic Floor Muscles1
 Levator ani
Perineum Muscles
 Ischiocavernosus
 Bulbospongiosus
 Deep transverse perineal
 Superficial transverse perineal
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Pelvic Floor Muscles2
Figure 7.21
© 2019 McGraw-Hill Education
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Muscles Acting on the Scapula
Trapezius
 shoulders and upper back
 extends neck and head
 Elevates, depress, retracts, rotates, and fixes scapula
Pectoralis minor
 Located in the chest
 Depresses scapula or elevates ribs
© 2019 McGraw-Hill Education
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2
Serratus anterior
• between ribs (1-9)
• Rotates and protracts scapula; elevates ribs
Levator scapulae
 elevates., retracts, and rotates scapula
 Laterally flexes the neck
© 2019 McGraw-Hill Education
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Muscles Acting on the Scapula
Major and Minor Rhomboids
 Retracts, rotates, and fixes scapula
© 2019 McGraw-Hill Education
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Muscles of the Humerus that Act on the
Forearm
Deltoid Muscle
 Flexes and extend shoulder; abducts and
medially and laterally rotates the arm
Triceps brachii
 3 heads, extends elbow, extend shoulders, adducts
the arm
Biceps brachii
 “flexing muscle”, flexes elbow and shoulder
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
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Upper Limb Muscles2
Brachialis
 flexes elbow
Latissimus dorsi
 lower back
 extends shoulder, adducts and medially rotates the
forearm
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
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Arm Muscles
Figure 7.23
(a) ©McGraw-Hill Education/Christine Eckel
© 2019 McGraw-Hill Education
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Forearm Muscles
Anterior Forearm Muscles
1. Palmaris longus- tightens skin of palm
2. Flexor carpi radialis- flex and abducts wrist
3. Flexor carpi ulnaris- flexes and adducts wrist
4. Flexor digitorum profundus-flex fingers & wrist
5. Flexor digitorum superficialis- flex fingers &
wrist
6. Pronator (Quadratus, Teres)- pronates forearm
© 2019 McGraw-Hill Education
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Muscles of the Forearm
Figure 7.24
© 2019 McGraw-Hill Education
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Posterior Forearm Muscle
Brachioradialis- flexes the elbow
Extensor carpi radialis brevis- extends &
abducts wrist
Extensor carpi radialis longus- extends &
abducts wrist
Extensor carpi ulnaris- extends & adducts wrist
Extensor digitorum- extends fingers and wrist
Supinator-supinates forearm
© 2019 McGraw-Hill Education
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Retinaculum
 covers the flexors and extensor tendons and
holds them in place around the wrist
Intrinsic Hand Muscles
 nineteen muscles which are located within
the hand
Interossei Muscles
 located in the metacarpal bones responsible
for abduction and adduction of fingers
© 2019 McGraw-Hill Education
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Muscles of the Forearm
Figure 7.24
© 2019 McGraw-Hill Education
135
Muscles of Hips and Thighs
Iliopsoas
 Anterior muscle that flexes hip
Gluteus Maximus
 buttocks
 extends hip, abducts and laterally rotates
the thigh
 Not ideal for IM injection
© 2019 McGraw-Hill Education
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Gluteus Medius
 abducts and medially rotates the thigh
 steadies pelvis during walking
 Ideal site of IM injection
Tensor Fasciae Latae
 A thick band of fascia on the lateral side
of the thigh
 It helps steady the femur on the tibia
when standing
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
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Muscles of the Upper Leg1
Quadriceps femoris is comprised of 4 thigh muscles:
1. Rectus femoris:
 front of thigh
 extends knee and flexes hip
2. Vastus lateralis:
 extends knee
3. Vastus medialis:
 extends knee
4. Vastus intermedius:
 extends knee
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
141
Sartorius
longest muscle in the body
tailor’s” muscle
 it flexed the hip and knee and rotates the
thigh laterally for sitting cross legged.
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
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Medial Compartment
Adductor Longus
 flexes the hip; adducts and laterally rotates
the thigh
Adductor Magnus
 extends the hip; adducts and laterally rotates
the thigh
Gracilis
adducts thigh and flexes knee
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
145
Figure 8.23b
© 2019 McGraw-Hill Education
146
Muscles of the Upper Leg2
Hamstring Muscles
back of thigh
flexes knee, rotates leg, extends hip
© 2019 McGraw-Hill Education
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HAMSTRINGS MUSCLES
Biceps femoris
 flexes the knee, extend the hip, laterally rotates the
leg
Semimembranosus
 flex knee and extend the hip, medially rotates the
leg
Semitendinosus
 flex knee and extend the hip, medially rotates
the leg
© 2019 McGraw-Hill Education
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Adductor Muscles
 adducts the thigh
© 2019 McGraw-Hill Education
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Figure 8.23b
© 2019 McGraw-Hill Education
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Muscles of the Hip and Thigh
Figure 7.26
© 2019 McGraw-Hill Education
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Muscles Causing Movement at the
Ankle and Foot
Anterior Compartment
Extensor digitorum longus
 extends the four lateral toes; dorsiflexes and
everts foot
Extensor hallucis longus
 extend great toes; dorsiflex and inverts foot
© 2019 McGraw-Hill Education
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Figure 7.8ef
© 2019 McGraw-Hill Education
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Figure 7.8g
© 2019 McGraw-Hill Education
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Muscles Causing Movement at the
Ankle and Foot
Anterior Compartment
Tibialis anterior
 dorsiflexes and inverts the foot
Fibularis/Peroneus tertius
 dorsiflexflexes and everts the foot
© 2019 McGraw-Hill Education
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Muscles of Lower Leg
Posterior Compartment
Gastrocnemius
 calf
 plantarflexes the foot; flexes the leg
 “toe dancer’s” muscle
Soleus
 attaches to ankle
 Plantar flexes the foot
© 2019 McGraw-Hill Education
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Figure 7.8g
© 2019 McGraw-Hill Education
157
Lower Leg Muscles
Figure 7.28
(d) ©Eric Wise
© 2019 McGraw-Hill Education
158
Lateral Compartment Muscles
Fibularis/Peroneus (longus, brevis,)
 Plantar flexes and everts the foot
© 2019 McGraw-Hill Education
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Effects of Aging In Muscles
 Reduction in muscle mass
 Slower response time for muscle contraction
 Reduced stamina
 Increased Recovery time
© 2019 McGraw-Hill Education
160
Diseases and Disorders of Muscular
System
Cramps
 painful spastic contraction of muscle due to
build up of lactic acid
Fibromyalgia
 chronic widespread pain in muscles with no
known cause
© 2019 McGraw-Hill Education
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Hypertrophy
 enlargement of a muscle due to increased
myofibrils due to increased muscle used
Atrophy
 decreased in muscle size due to
decreased myofibrils because of disuse
muscle as in paralysis
Tendinitis
 inflammation of a tendon or its attachment
joint due to overuse of a muscle
© 2019 McGraw-Hill Education
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Muscular dystrophy
 a group of inherited muscle-destroying
disease that affect muscle group.
 The most common & serious form is
Duchenne’s muscular dystrophy.
© 2019 McGraw-Hill Education
163
Duchenne Muscular Dystrophy
 results from abnormal gene on the X
chromosome
 The gene is carried by female but DMD
common on males
 DMD gene is responsible for producing a
protein called DYSTROPIN
© 2019 McGraw-Hill Education
164
DMD
 part of the gene is missing and the protein in
produces is nonfunctional resulting to
progressive muscular weakness and muscular
contractures.
© 2019 McGraw-Hill Education
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SYMPTOMS
 Muscular weakness
 Muscle atrophy
 Contractures
© 2019 McGraw-Hill Education
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Nervous
 Mental retardation
Cardiovascualr
 Affects cardiac muscles leading heart failure
Respiratory
 Weakness of the respiratory muscles leading
to respiratory failure
© 2019 McGraw-Hill Education
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Digestive
 Affects smooth muscle and reduce the ability
of smooth muscle to contract
Urinary
 Reduced smooth muscle function
 Increase UTI
© 2019 McGraw-Hill Education
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Skeletal
 Shortened inflexible muscles
 Kyphoscoliosis- sever curvature of the
vertebra laterally or anteriorly
 Wheelchair dependency
© 2019 McGraw-Hill Education
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Duchenne Muscular Dystrophy
© 2019 McGraw-Hill Education
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Treatment
 Physical therapy primarily involves exercise
 No effective treatment to prevent
© 2019 McGraw-Hill Education
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Myasthenia Gravis
 characterized by drooping of the upper eyelid
difficulty of swallowing & talking and generalized
muscle weakness and fatigability.
 Death occurs as a result of the inability of the
respiratory muscle to function (respiratory failure).
© 2019 McGraw-Hill Education
172
© 2019 McGraw-Hill Education
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© 2019 McGraw-Hill Education
174

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Ch07 lecture ppt_a (1)

  • 1. Seeley’s ESSENTIALS OF Anatomy & Physiology Tenth Edition Cinnamon Vanputte Jennifer Regan Andrew Russo See separate PowerPoint slides for all figures and tables pre-inserted into PowerPoint without notes. © 2019 McGraw-Hill Education. All rights reserved. Authorized only for instructor use in the classroom. No reproduction or further distribution permitted without the prior written consent of McGraw-Hill Education.
  • 2. © 2019 McGraw-Hill Education 2 Chapter 7 Muscular System Lecture Outline
  • 3. © 2019 McGraw-Hill Education 3 Types of Muscles Skeletal attached to bones striated voluntarily controlled Cardiac located in the heart striated involuntarily controlled
  • 4. © 2019 McGraw-Hill Education 4 Types of Muscles Smooth Located in blood vessels, hollow organs Non-striated involuntarily controlled
  • 5. © 2019 McGraw-Hill Education 5 Comparison of Skeletal, Cardiac, and Smooth Muscles Characteristics Skeletal Cardiac Smooth Body location Attached to bones or, for some facial muscles to skin Walls of the heart Mostly in walls of hollow visceral organs Cell shape and appearance Single, very long, cylindrical, multi- nucleate cells with very obvious striations Branching chains of cells; uninucleate, striations; intercalated discs Single, fusiform, uninucleate, no striations Connective tissue components Epimysium, perimysium, and endomysium Endomysium attached to the fibrous skeleton of the heart Endomysium Regulation of contraction Voluntary, via nervous system control Involuntary; the heart has pacemaker; nervous system control; hormone Involuntary; nervous system controls; hormones, chemicals
  • 6. © 2019 McGraw-Hill Education 6 Characteristics Skeletal Cardiac Smooth Speed of Contraction Slow to fast slow Very slow Rhythmic contraction No Yes Yes, in some
  • 7. © 2019 McGraw-Hill Education 7
  • 8. © 2019 McGraw-Hill Education 8 The Muscular System Functions  Movement  Maintain posture  Respiration  Production of body heat  Communication  Heart beat  Contraction of organs and vessels Figure 7.1
  • 9. © 2019 McGraw-Hill Education 9 Properties of Muscles Contractility  the ability of muscle to shorten forcefully, or contract Excitability  the capacity of muscle to respond to a stimulus
  • 10. © 2019 McGraw-Hill Education 10 Properties of Muscles Extensibility  ability to be stretched beyond it normal resting length and still be able to contract Elasticity  ability of the muscle to recoil to its original resting length after it has been stretched
  • 11. © 2019 McGraw-Hill Education 11 Skeletal Muscle Structure1  Skeletal muscle, or striated muscle, with its associated connective tissue, constitutes approximately 40% of body weight.  Skeletal muscle is so named because they are attached to the skeletal system.  Some skeletal muscles attach to the skin or connective tissue sheets.
  • 12. © 2019 McGraw-Hill Education 12 Skeletal Muscle Structure2  Skeletal muscle is also called striated muscle because transverse bands, or striations.
  • 13. © 2019 McGraw-Hill Education 13 Connective Tissue Coverings  Epimysium a connective tissue sheath that surround each skeletal muscle  A skeletal muscle is subdivided into groups of muscle cells, termed fascicles.  Perimysium -surround the fascicle.  Endomysium - surround each skeletal muscle cell (fiber)
  • 14. © 2019 McGraw-Hill Education 14 Muscle Fiber Structure1  a single cylindrical cell, with several nuclei located at its periphery.  It range in length 1 cm to 30 cm and are generally 0.15 mm in diameter.  Skeletal muscle fibers contain several nuclei that are located at the periphery of the fiber.  The sarcolemma (cell membrane) has many tubelike inward folds, called transverse tubules, or T tubules.
  • 15. © 2019 McGraw-Hill Education 15 Muscle Fiber Structure2  T tubules occur at regular intervals along the muscle fiber and extend into the center of the muscle fiber.  The T tubules are associated with enlarged portions of the smooth endoplasmic reticulum called the sarcoplasmic reticulum.  The enlarged portions are called terminal cisternae.  T tubules connect the sarcolemma to the terminal cisternae to form a muscle triad.
  • 16. © 2019 McGraw-Hill Education 16 Muscle Fiber Structure3  Sarcoplasm it the cytoplasm of a muscle fiber which contains many bundles of protein filaments.  Myofibrils are bundles of protein filaments.  Myofibrils consist of the myofilaments, actin and myosin.
  • 17. © 2019 McGraw-Hill Education 17 Figure 8.1
  • 18. © 2019 McGraw-Hill Education 18 Structure of Skeletal Muscle Figure 7.2
  • 19. © 2019 McGraw-Hill Education 19 Sarcomere1  the basic structural and functional unit of a skeletal muscle capable of contracting.  Z Disks - form a network of protein fibers that serve as an anchor for actin myofilaments and separate one sarcomere from the next.  A sarcomere extends from one Z disk to the next Z disk.
  • 20. © 2019 McGraw-Hill Education 20 The Sarcomere2  The organization of actin and myosin myofilaments gives skeletal muscle its striated appearance and gives it the ability to contract.  The myofilaments slide past each other, causing the sarcomeres to shorten.  Each sarcomere consists of two light-staining bands separated by a dark-staining band.
  • 21. © 2019 McGraw-Hill Education 21 Figure 8.2c
  • 22. © 2019 McGraw-Hill Education 22 The Sarcomere3  I bands -light bands, consist only of actin myofilaments that extends toward the center of the sarcomere to the ends of the myosin myofilaments.  A bands -dark staining bands that extend the length of the myosin myofilaments.  Actin and myosin myofilaments overlap for some distance on both ends of the A band that causes the contraction. 
  • 23. © 2019 McGraw-Hill Education 23 Figure 8.2c
  • 24. © 2019 McGraw-Hill Education 24 The Sarcomere4  Actin myofilaments are made up of three components: Actin, Troponin, and Tropomyosin.  Troponin -molecules have binding sites for Ca2 +  Tropomyosin - filaments block the myosin myofilament binding sites on the actin myofilaments.  Myosin myofilaments, or thick myofilaments, resemble bundles of tiny golf clubs.  Myosin heads have ATP binding sites, ATPase and attachment spots for actin.
  • 25. © 2019 McGraw-Hill Education 25 Figure 8.3a
  • 26. © 2019 McGraw-Hill Education 26 Figure 8.3b
  • 27. © 2019 McGraw-Hill Education 27 Sliding Filament Mechanism During contraction myosin heads bind actin sites Pull and slide actin molecules (and Z-discs) toward H-zone I-bands and H-zones narrow Sliding generates force and shortens sarcomeres.
  • 28. © 2019 McGraw-Hill Education 28 Figure 8.4
  • 29. © 2019 McGraw-Hill Education 29 Skeletal Muscle Fiber Figure 7.3
  • 30. © 2019 McGraw-Hill Education 30 Excitability of Muscle Fibers  Muscle cells (fibers) have a resting membrane potential, but can also perform action potentials. Resting Membrane Potential  the inside of the membrane is negatively charged and the outside of the membrane is positively charged. Action potentials  due to the membrane having gated channels.
  • 31. © 2019 McGraw-Hill Education 31 Resting Membrane Potential1 The resting membrane potential exists because of:  The concentration of K+ being higher on the inside of the cell membrane and the concentration of Na+ being higher on the outside  The presence of many negatively charged molecules, such as proteins, inside the cell that are too large to exit the cell  The presence of leak protein channels in the membrane that are more permeable to K+ than it is to Na+
  • 32. © 2019 McGraw-Hill Education 32 Resting Membrane Potential2  Na+ tends to diffuse into the cell and K+ tends to diffuse out.  In order to maintain the resting membrane potential, the sodium-potassium pump recreates the Na+ and K+ ion gradient by pumping Na+ out of the cell and K+ into the cell.
  • 33. © 2019 McGraw-Hill Education 33 Resting Membrane Potential3 Figure 7.4 (1)
  • 34. © 2019 McGraw-Hill Education 34 Action Potential1  Resting membrane potential must be changed to an action potential.  Changes in the resting membrane potential occur when gated cell membrane channels open.  In a skeletal muscle fiber, a nerve impulse triggers gated Na+ channels to open and Na+ diffuses into the cell down its concentration gradient and toward the negative charges inside the cell.
  • 35. © 2019 McGraw-Hill Education 35 Action Potential2  The entry of Na+ causes the inside of the cell membrane to become more positive than when the cell is at resting membrane potential.  This increase in positive charge inside the cell membrane is called DEPOLARIZATION.  If the depolarization changes the membrane potential to a value called threshold, an action potential is triggered.  An action potential is a rapid change in charge across the cell membrane.
  • 36. © 2019 McGraw-Hill Education 36 Action Potential3  Depolarization during the action potential is when the inside of the cell membrane becomes more positively charged than the outside of the cell membrane.  Near the end of depolarization, the positive charge causes gated Na+ channels to close and gated K+ channels to open.  Opening of gated K+ channels starts repolarization of the cell membrane.
  • 37. © 2019 McGraw-Hill Education 37 Action Potential4  Repolarization is due to the exit of K+ from the cell.  The outward diffusion of K+ returns the cell to its resting membrane conditions and the action potential ends.  In a muscle fiber, an action potential results in muscle contraction.
  • 38. © 2019 McGraw-Hill Education 38 Depolarization  change in charges inside becomes more + and outside more –  Na+ channels open Figure 7.4 (2)
  • 39. © 2019 McGraw-Hill Education 39 Repolarization  Na+ channels close  change back to resting potential Figure 7.4 (3)
  • 40. © 2019 McGraw-Hill Education 40 Ion Channels and Action Potentials Figure 7.4
  • 41. © 2019 McGraw-Hill Education 41 Nerve Supply & Muscle Fiber Stimulation1  Motor neuron - a nerve cell stimulates muscle cells.  Neuromuscular junction-a synapse where a the fiber of a nerve connects with a muscle fiber.  Synapse refers to the cell-to-cell junction between a nerve cell and either another nerve cell or an effector cell.  Motor unit -a group of muscle fibers that a motor neuron stimulates.
  • 42. © 2019 McGraw-Hill Education 42 Nerve Supply2  Presynaptic terminal is the end of a neuron cell axon fiber.  Synaptic cleft is the space between the presynaptic terminal and postsynaptic membrane.  Postsynaptic membrane is the muscle fiber membrane (sarcolemma).  Synaptic vesicle is a vesicle in the presynaptic terminal that stores and releases neurotransmitter chemicals.
  • 43. © 2019 McGraw-Hill Education 43 Nerve Supply3  Neurotransmitters - are chemicals that stimulate or inhibit postsynaptic cells.  Acetylcholine - the neurotransmitter that stimulates skeletal muscles.  Acetylcholinesterase- an enzyme that breaks down the acetylcholine to prevent overstimulation of muscle fiber.
  • 44. © 2019 McGraw-Hill Education 44 Neuromuscular Junction Figure 7.5 (b) ©Ed Reschke/Photolibrary/Getty Images
  • 45. © 2019 McGraw-Hill Education 45 Muscle Contraction1 1. An action potential travels down motor neuron to presynaptic terminal causing Ca2+ channels to open. 2. Ca2+ causes synaptic vesicles to release acetylcholine into synaptic cleft. 3. Acetylcholine binds to receptor sites on Na+ channels, Na+ channels open, and Na+ rushes into postsynaptic terminal (depolarization).
  • 46. © 2019 McGraw-Hill Education 46 Function of the Neuromuscular Junction Figure 7.6
  • 47. © 2019 McGraw-Hill Education 47 Muscle Contraction2 4. Na+ causes sarcolemma and t-tubules to increase the permeability of sarcoplasmic reticulum which releases stored calcium. 5. Ca2+ binds to troponin which is attached to actin. 6. Ca2+ binding to troponin causes tropomyosin to move exposing attachment sites for myosin. 7. Myosin heads bind to actin.
  • 48. © 2019 McGraw-Hill Education 48 Muscle Contraction3 8. ATP is released from myosin heads and heads bend toward center of sarcomere. 9. Bending forces actin to slide over myosin. 10. Acetylcholinesterase (enzyme breaks down acetylcholine) is released, Na+ channels close, and muscle contraction stops.
  • 49. © 2019 McGraw-Hill Education 49 Skeletal Muscle Excitation1 Figure 7.8 (1)
  • 50. © 2019 McGraw-Hill Education 50 Skeletal Muscle Excitation2 Figure 7.8 (2,3)
  • 51. © 2019 McGraw-Hill Education 51 Skeletal Muscle Excitation3 Figure 7.8 (4)
  • 52. © 2019 McGraw-Hill Education 52 Skeletal Muscle Excitation4 Figure 7.8 (5,6)
  • 53. © 2019 McGraw-Hill Education 53 Skeletal Muscle Excitation5 Figure 7.8 (6,7,8)
  • 54. © 2019 McGraw-Hill Education 54 Skeletal Muscle Excitation6 Figure 7.8 (9)
  • 55. © 2019 McGraw-Hill Education 55 Muscle Twitch1  is a single contraction of a muscle fiber in response to a stimulus.  has three phases: latent phase, contraction phase, and relaxation phase.
  • 56. © 2019 McGraw-Hill Education 56 Muscle Twitch1 Latent phase  the time between the application of a stimulus and the beginning of contraction. Contraction phase  the time during which the muscle contracts and the Relaxation phase  is the time during which the muscle relaxes.
  • 57. © 2019 McGraw-Hill Education 57 Muscle Twitch2 Figure 7.10
  • 58. © 2019 McGraw-Hill Education 58 Summation and Recruitment Summation- the individual muscles contract more forcefully. Tetanus is a sustained contraction that occurs when the frequency of stimulation is so rapid that no relaxation occurs. Recruitment is the stimulation of several motor units which increases the total number of muscle fibers contracting.
  • 59. © 2019 McGraw-Hill Education 59 Multiple-Wave Summation Figure 7.11
  • 60. © 2019 McGraw-Hill Education 60 Skeletal Muscle Fiber Types1 Slow twitch fibers • contract slowly • fatigue slowly • have a considerable amount of myoglobin • use aerobic respiration • are dark in color • used by long distance runners
  • 61. © 2019 McGraw-Hill Education 61 Skeletal Muscle Fiber Types2 Fast twitch fibers • contract quickly • fatigue quickly • use anaerobic respiration • energy from glycogen • light color • used by sprinters
  • 62. © 2019 McGraw-Hill Education 62 Energy Requirements for Muscle Contractions 1. Aerobic production of ATP during most exercise and normal conditions. 2. Anaerobic production of ATP during intensive short-term work 3. Conversion of a molecule called creatine phosphate to ATP 4. Conversion of two ADP to one ATP and one AMP (adenosine monophosphate) during heavy exercise
  • 63. © 2019 McGraw-Hill Education 63 ATP Production in Resting & Exercise Muscle REST  1. ATP is produced by aerobic respiration  2. Small amounts of ATP are used by muscle contractions that maintain muscle tone  3. Excess ATP is used to produced creatine phosphate
  • 64. © 2019 McGraw-Hill Education 64 EXERCISE 4. As exercise begins, ATP already in the muscle cells is used first, but during moderate exercise, aerobic respiration provides most of the ATP necessary for muscle contraction. 5. During times of extreme exercise, anaerobic respiration provides small amount of ATP that can sustain muscle contraction for brief periods. 6. Energy store in creatine phosphate can also be used to produce ATP. 7. Throughout the time of exercise, ATP from all of these sources (4-6) provides energy for active muscle contraction.
  • 65. © 2019 McGraw-Hill Education 65 Muscle Fatigue1  is a temporary state of reduced work capacity.  Without fatigue, muscle fibers would be worked to the point of structural damage to them and their supportive tissues.
  • 66. © 2019 McGraw-Hill Education 66 Mechanisms of Fatigue  Acidosis and ATP depletion due to increased ATP consumption or a decreased ATP production  Oxidative stress- buildup of excess reactive oxygen species (ROS; free radicals)  Local inflammatory reactions
  • 67. © 2019 McGraw-Hill Education 67 Types of Contractions1 Isometric contraction  has an increase in muscle tension, but no change in length. Isotonic contraction  has a change in muscle length with no change in tension.
  • 68. © 2019 McGraw-Hill Education 68 Types of Contractions2 Concentric contractions  are isotonic contractions in which muscle tension increases as the muscle shortens. Eccentric contractions  are isotonic contractions in which tension is maintained in a muscle, but the opposing resistance causes the muscle to lengthen.
  • 69. © 2019 McGraw-Hill Education 69 ISOTONIC EXERCISE  There is a change in muscle length, no change in tension. ISOMETRIC EXERCISE  increase in muscle tension, but no change in length.
  • 70. © 2019 McGraw-Hill Education 70 Muscle Tone  is the constant tension produced by body muscles over long periods of time.  responsible for keeping the back and legs straight, the head in an upright position, and the abdomen from bulging. Disturbance in muscle tone  Atrophy  Flaccidity
  • 71. © 2019 McGraw-Hill Education 71
  • 72. © 2019 McGraw-Hill Education 72 Smooth Muscle  are non-striated small, spindle-shaped muscle cells, usually with one nucleus per cell.  Contain less actin and the myofilaments are not organized into sarcomeres.  The cells comprise organs controlled involuntarily, except the heart.  Neurotransmitter substances, hormones, and other substances can stimulate smooth muscle.
  • 73. © 2019 McGraw-Hill Education 73 Cardiac Muscle1  are long, striated, and branching, with usually only one nucleus per cell.  is striated as a result of the sarcomere arrangement  contraction is autorhythmic.
  • 74. © 2019 McGraw-Hill Education 74 Cardiac Muscle  muscle cells are connected to one another by specialized structures that include desmosomes and gap junctions called intercalated disks.  Cardiac muscle cells function as a single unit in that action potential in one cardiac muscle cell can stimulate action potentials in adjacent cells causing to contract all together.
  • 75. © 2019 McGraw-Hill Education 75 Arrangement of Fascicles Circular  arranged in concentric rings or in circle around the opening.  Acts as sphincters to open and close the opening  Ex: orbicularis oris, orbicularis oculi
  • 76. © 2019 McGraw-Hill Education 76
  • 77. © 2019 McGraw-Hill Education 77 Arrangement of Fascicles Convergent  fascicles converge toward a single insertion tendon  such muscle is triangular or fan-shaped.  Ex: pectoralis major and minor
  • 78. © 2019 McGraw-Hill Education 78
  • 79. © 2019 McGraw-Hill Education 79 Arrangement of Fascicles Parallel  the length of the fascicles run parallel to one another to the long axis of the muscle.  Ex: trapezium, quadrate, rhomboidal
  • 80. © 2019 McGraw-Hill Education 80
  • 81. © 2019 McGraw-Hill Education 81 Pennate  Fascicles originate from a tendon that runs the length of the entire muscle.  Unipennate - fascicles on only one side of the tendon. (Palmar interosseus)  Bipennate- fascicles on both sides of the tendon. (Rectus femoris)  Multipennate- fascicles arranged at many places around the central tendon (deltoid)
  • 82. © 2019 McGraw-Hill Education 82
  • 83. © 2019 McGraw-Hill Education 83 Fusiform  fascicles lie parallel to long axis of muscle  Ex: biceps brachii, triceps brachii
  • 84. © 2019 McGraw-Hill Education 84
  • 85. © 2019 McGraw-Hill Education 85 Skeletal Muscles1 Figure 7.14a
  • 86. © 2019 McGraw-Hill Education 86 Skeletal Muscles2 Figure 7.14b
  • 87. © 2019 McGraw-Hill Education 87 Skeletal Muscle Anatomy Tendon - connects skeletal muscle to bone. Aponeuroses- are broad, sheetlike tendons. Retinaculum- is a band of connective tissue that holds down the tendons at each wrist and ankle. Origin – the most stationary, fixed, end of a muscle. Insertion -is the end of the muscle attached to the bone undergoing the greatest movement.
  • 88. © 2019 McGraw-Hill Education 88 Skeletal Muscle Anatomy2 Belly  the part of the muscle between the origin and the insertion Agonists  a single or group of muscles working together. Antagonists  a muscle or group of muscles that oppose muscle actions.
  • 89. © 2019 McGraw-Hill Education 89
  • 90. © 2019 McGraw-Hill Education 90 Synergist  members of a group of muscles working together to produced movement  Brachii and brachialis  Deltoid, biceps brachii, and pectoralis major
  • 91. © 2019 McGraw-Hill Education 91 Muscle Attachment Figure 7.13
  • 92. © 2019 McGraw-Hill Education 92 Prime Mover  one muscle plays the major role to accomplish the desired movement.  Ex: Brachialis is the prime mover in flexing the elbow FIXATORS  Are muscles that hold one bone in place  stabilize origin of prime mover  Scapular muscles acts as a fixator to hold the scapula in place.
  • 93. © 2019 McGraw-Hill Education 93 Nomenclature1 Muscles are named according to: 1. Location – a pectoralis muscle is located in the chest. 2. Size – the size could be large or small, short or long. 3. Shape - the shape could be triangular, quadrate, rectangular, or round. 4. Orientation of fascicles – fascicles could run straight (rectus) or at an angle (oblique).
  • 94. © 2019 McGraw-Hill Education 94 Nomenclature2 5. Origin and insertion. The sternocleidomastoid has its origin on the sternum and clavicle and its insertion on the mastoid process of the temporal bone. 6. Number of heads. A biceps muscle has two heads (origins), and a triceps muscle has three heads (origins). 7. Function. Abductors and adductors are the muscles that cause abduction and adduction movements.
  • 95. © 2019 McGraw-Hill Education 95 Figure 8-13a
  • 96. © 2019 McGraw-Hill Education 96 Figure 8-13b
  • 97. © 2019 McGraw-Hill Education 97 Muscles of the Head and Neck  Facial muscles,  Mastication or chewing tongue  Swallowing muscles  Eyes muscles  head and neck muscles
  • 98. © 2019 McGraw-Hill Education 98 Figure 8.14
  • 99. © 2019 McGraw-Hill Education 99 Facial Muscles BUCCINATOR  Wall of the cheeks  flattens the cheek (as in whistling or blowing a trumpet)  “Kissing Muscle or Trumpeter’s muscle  Compresses cheek to hold food teeth
  • 100. © 2019 McGraw-Hill Education 100 Depressor anguli oris  Lower corners of mouth/depresses the corner of mouth Levator Labii superioris  Elevates one side of the upper lip OccipitoFrontalis  Moves scalp, raises eyebrows, and to wrinkle your forehead
  • 101. © 2019 McGraw-Hill Education 101 Orbicularis oris  closes the mouth and protrudes the lips,  the “kissing” muscle Orbicularis oculi  close the eyes, squint, blink, and wink. Zygomaticus  the “smiling” muscle  elevate the upper lip and corner of the mouth.
  • 102. © 2019 McGraw-Hill Education 102 Muscles of Facial Expression and Mastication Figure 7.16 ©McGraw-Hill Education/ Christine Eckel
  • 103. © 2019 McGraw-Hill Education 103 CHEWING MUSCLES 1. Masseter - closes the jaw by elevating and pushing the mandible anteriorly 2. Temporalis -elevates and draws mandible posteriorly. 3. Ptergoid 1. Lateral- pushes the mandible anteriorly and depresses mandible, close the jaw 2. Medial- pushes the mandible anteriorly and elevates mandible; closes the jaw
  • 104. © 2019 McGraw-Hill Education 104 Tongue and Swallowing Muscles Tongue Muscles  Intrinsic- change the shape of the tongue  Extrinsic- moves the tongue Hyoid Muscles Suprahyoid (geniohyoid, stylohyoid, hyoglossus)  elevates or stabilized hyoid Infrahyoid- depresses or stabilizes hyoid
  • 105. © 2019 McGraw-Hill Education 105 Tongue and Swallowing Muscles Figure 7.17
  • 106. © 2019 McGraw-Hill Education 106 Deep Neck Muscles 1. Neck Flexors  originate on the anterior side of the vertebra which flex the head and neck 2. Neck Extensor  originate on the posterior side of the vertebra that extend the head and neck
  • 107. © 2019 McGraw-Hill Education 107 Sternocleidomastoid  Individually rotate the head; together it flex the neck Platysma  pull the corners of the mouth inferiorly Trapezius  Extends and laterally flexes the neck
  • 108. © 2019 McGraw-Hill Education 108 Figure 8-13b
  • 109. © 2019 McGraw-Hill Education 109 Figure 8.14
  • 110. © 2019 McGraw-Hill Education 110 Trunk Muscles  Vertebral column,  Thorax,  Abdominal wall and  Pelvic floor.
  • 111. © 2019 McGraw-Hill Education 111 Trunk Muscles Muscles of the Vertebral Column Erector Spinae  Extends vertebral column & maintain posture.  Divides in 3 column; Iliocostalis, longissimus, Spinalis.
  • 112. © 2019 McGraw-Hill Education 112 Deep Neck and Back Muscles Figure 7.18
  • 113. © 2019 McGraw-Hill Education 113 Deep Back Muscles  Located between spinous and transverse processes adjacent to vertebra  Responsible for movement of vertebral column including extension, lateral flexion and rotation  torn or stretched od these muscles cause sprain and strain.
  • 114. © 2019 McGraw-Hill Education 114 Thoracic Muscles Scalenes- elevates the ribs, during inspiration External intercostals- elevate ribs for inspiration Internal intercostals- depress ribs during forced expiration Diaphragm- moves during quiet breathing
  • 115. © 2019 McGraw-Hill Education 115 Muscles of the Thorax Figure 7.19
  • 116. © 2019 McGraw-Hill Education 116 Abdominal Wall Muscles1 Rectus abdominis  center of abdomen  compresses abdomen External abdominal oblique  sides of abdomen  compresses abdomen
  • 117. © 2019 McGraw-Hill Education 117 Abdominal Wall Muscles2 Internal abdominal oblique  compresses abdomen Transverse abdominis  compresses abdomen
  • 118. © 2019 McGraw-Hill Education 118 Muscles of the Anterior Abdominal Wall Figure 7.20
  • 119. © 2019 McGraw-Hill Education 119 Pelvic Floor Muscles1  Levator ani Perineum Muscles  Ischiocavernosus  Bulbospongiosus  Deep transverse perineal  Superficial transverse perineal
  • 120. © 2019 McGraw-Hill Education 120 Pelvic Floor Muscles2 Figure 7.21
  • 121. © 2019 McGraw-Hill Education 121 Muscles Acting on the Scapula Trapezius  shoulders and upper back  extends neck and head  Elevates, depress, retracts, rotates, and fixes scapula Pectoralis minor  Located in the chest  Depresses scapula or elevates ribs
  • 122. © 2019 McGraw-Hill Education 122 2 Serratus anterior • between ribs (1-9) • Rotates and protracts scapula; elevates ribs Levator scapulae  elevates., retracts, and rotates scapula  Laterally flexes the neck
  • 123. © 2019 McGraw-Hill Education 123 Muscles Acting on the Scapula Major and Minor Rhomboids  Retracts, rotates, and fixes scapula
  • 124. © 2019 McGraw-Hill Education 124 Muscles of the Humerus that Act on the Forearm Deltoid Muscle  Flexes and extend shoulder; abducts and medially and laterally rotates the arm Triceps brachii  3 heads, extends elbow, extend shoulders, adducts the arm Biceps brachii  “flexing muscle”, flexes elbow and shoulder
  • 125. © 2019 McGraw-Hill Education 125
  • 126. © 2019 McGraw-Hill Education 126
  • 127. © 2019 McGraw-Hill Education 127 Upper Limb Muscles2 Brachialis  flexes elbow Latissimus dorsi  lower back  extends shoulder, adducts and medially rotates the forearm
  • 128. © 2019 McGraw-Hill Education 128
  • 129. © 2019 McGraw-Hill Education 129 Arm Muscles Figure 7.23 (a) ©McGraw-Hill Education/Christine Eckel
  • 130. © 2019 McGraw-Hill Education 130 Forearm Muscles Anterior Forearm Muscles 1. Palmaris longus- tightens skin of palm 2. Flexor carpi radialis- flex and abducts wrist 3. Flexor carpi ulnaris- flexes and adducts wrist 4. Flexor digitorum profundus-flex fingers & wrist 5. Flexor digitorum superficialis- flex fingers & wrist 6. Pronator (Quadratus, Teres)- pronates forearm
  • 131. © 2019 McGraw-Hill Education 131 Muscles of the Forearm Figure 7.24
  • 132. © 2019 McGraw-Hill Education 132 Posterior Forearm Muscle Brachioradialis- flexes the elbow Extensor carpi radialis brevis- extends & abducts wrist Extensor carpi radialis longus- extends & abducts wrist Extensor carpi ulnaris- extends & adducts wrist Extensor digitorum- extends fingers and wrist Supinator-supinates forearm
  • 133. © 2019 McGraw-Hill Education 133 Retinaculum  covers the flexors and extensor tendons and holds them in place around the wrist Intrinsic Hand Muscles  nineteen muscles which are located within the hand Interossei Muscles  located in the metacarpal bones responsible for abduction and adduction of fingers
  • 134. © 2019 McGraw-Hill Education 134 Muscles of the Forearm Figure 7.24
  • 135. © 2019 McGraw-Hill Education 135 Muscles of Hips and Thighs Iliopsoas  Anterior muscle that flexes hip Gluteus Maximus  buttocks  extends hip, abducts and laterally rotates the thigh  Not ideal for IM injection
  • 136. © 2019 McGraw-Hill Education 136 Gluteus Medius  abducts and medially rotates the thigh  steadies pelvis during walking  Ideal site of IM injection Tensor Fasciae Latae  A thick band of fascia on the lateral side of the thigh  It helps steady the femur on the tibia when standing
  • 137. © 2019 McGraw-Hill Education 137
  • 138. © 2019 McGraw-Hill Education 138
  • 139. © 2019 McGraw-Hill Education 139 Muscles of the Upper Leg1 Quadriceps femoris is comprised of 4 thigh muscles: 1. Rectus femoris:  front of thigh  extends knee and flexes hip 2. Vastus lateralis:  extends knee 3. Vastus medialis:  extends knee 4. Vastus intermedius:  extends knee
  • 140. © 2019 McGraw-Hill Education 140
  • 141. © 2019 McGraw-Hill Education 141 Sartorius longest muscle in the body tailor’s” muscle  it flexed the hip and knee and rotates the thigh laterally for sitting cross legged.
  • 142. © 2019 McGraw-Hill Education 142
  • 143. © 2019 McGraw-Hill Education 143 Medial Compartment Adductor Longus  flexes the hip; adducts and laterally rotates the thigh Adductor Magnus  extends the hip; adducts and laterally rotates the thigh Gracilis adducts thigh and flexes knee
  • 144. © 2019 McGraw-Hill Education 144
  • 145. © 2019 McGraw-Hill Education 145 Figure 8.23b
  • 146. © 2019 McGraw-Hill Education 146 Muscles of the Upper Leg2 Hamstring Muscles back of thigh flexes knee, rotates leg, extends hip
  • 147. © 2019 McGraw-Hill Education 147 HAMSTRINGS MUSCLES Biceps femoris  flexes the knee, extend the hip, laterally rotates the leg Semimembranosus  flex knee and extend the hip, medially rotates the leg Semitendinosus  flex knee and extend the hip, medially rotates the leg
  • 148. © 2019 McGraw-Hill Education 148 Adductor Muscles  adducts the thigh
  • 149. © 2019 McGraw-Hill Education 149 Figure 8.23b
  • 150. © 2019 McGraw-Hill Education 150 Muscles of the Hip and Thigh Figure 7.26
  • 151. © 2019 McGraw-Hill Education 151 Muscles Causing Movement at the Ankle and Foot Anterior Compartment Extensor digitorum longus  extends the four lateral toes; dorsiflexes and everts foot Extensor hallucis longus  extend great toes; dorsiflex and inverts foot
  • 152. © 2019 McGraw-Hill Education 152 Figure 7.8ef
  • 153. © 2019 McGraw-Hill Education 153 Figure 7.8g
  • 154. © 2019 McGraw-Hill Education 154 Muscles Causing Movement at the Ankle and Foot Anterior Compartment Tibialis anterior  dorsiflexes and inverts the foot Fibularis/Peroneus tertius  dorsiflexflexes and everts the foot
  • 155. © 2019 McGraw-Hill Education 155 Muscles of Lower Leg Posterior Compartment Gastrocnemius  calf  plantarflexes the foot; flexes the leg  “toe dancer’s” muscle Soleus  attaches to ankle  Plantar flexes the foot
  • 156. © 2019 McGraw-Hill Education 156 Figure 7.8g
  • 157. © 2019 McGraw-Hill Education 157 Lower Leg Muscles Figure 7.28 (d) ©Eric Wise
  • 158. © 2019 McGraw-Hill Education 158 Lateral Compartment Muscles Fibularis/Peroneus (longus, brevis,)  Plantar flexes and everts the foot
  • 159. © 2019 McGraw-Hill Education 159 Effects of Aging In Muscles  Reduction in muscle mass  Slower response time for muscle contraction  Reduced stamina  Increased Recovery time
  • 160. © 2019 McGraw-Hill Education 160 Diseases and Disorders of Muscular System Cramps  painful spastic contraction of muscle due to build up of lactic acid Fibromyalgia  chronic widespread pain in muscles with no known cause
  • 161. © 2019 McGraw-Hill Education 161 Hypertrophy  enlargement of a muscle due to increased myofibrils due to increased muscle used Atrophy  decreased in muscle size due to decreased myofibrils because of disuse muscle as in paralysis Tendinitis  inflammation of a tendon or its attachment joint due to overuse of a muscle
  • 162. © 2019 McGraw-Hill Education 162 Muscular dystrophy  a group of inherited muscle-destroying disease that affect muscle group.  The most common & serious form is Duchenne’s muscular dystrophy.
  • 163. © 2019 McGraw-Hill Education 163 Duchenne Muscular Dystrophy  results from abnormal gene on the X chromosome  The gene is carried by female but DMD common on males  DMD gene is responsible for producing a protein called DYSTROPIN
  • 164. © 2019 McGraw-Hill Education 164 DMD  part of the gene is missing and the protein in produces is nonfunctional resulting to progressive muscular weakness and muscular contractures.
  • 165. © 2019 McGraw-Hill Education 165 SYMPTOMS  Muscular weakness  Muscle atrophy  Contractures
  • 166. © 2019 McGraw-Hill Education 166 Nervous  Mental retardation Cardiovascualr  Affects cardiac muscles leading heart failure Respiratory  Weakness of the respiratory muscles leading to respiratory failure
  • 167. © 2019 McGraw-Hill Education 167 Digestive  Affects smooth muscle and reduce the ability of smooth muscle to contract Urinary  Reduced smooth muscle function  Increase UTI
  • 168. © 2019 McGraw-Hill Education 168 Skeletal  Shortened inflexible muscles  Kyphoscoliosis- sever curvature of the vertebra laterally or anteriorly  Wheelchair dependency
  • 169. © 2019 McGraw-Hill Education 169 Duchenne Muscular Dystrophy
  • 170. © 2019 McGraw-Hill Education 170 Treatment  Physical therapy primarily involves exercise  No effective treatment to prevent
  • 171. © 2019 McGraw-Hill Education 171 Myasthenia Gravis  characterized by drooping of the upper eyelid difficulty of swallowing & talking and generalized muscle weakness and fatigability.  Death occurs as a result of the inability of the respiratory muscle to function (respiratory failure).
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