The document summarizes the key developments and events of the Renaissance period in Europe between the 14th and 16th centuries. It describes the transition from the medieval to the modern era, the rise of humanism and secular thought during this period in Italy and other parts of Europe. It also discusses the growth of powerful monarchies in countries like France and the exploration and colonization of the Americas by powers like Spain and Portugal that established new global empires and trade networks and had major social, economic and political impacts.