Chapter 3

Digestion, Absorption, and
        Transport




        © 2009 Cengage - Wadsworth
Digestion

• Digestion is the process of breaking
  down foods into nutrients to prepare
  for absorption while overcoming 7
  challenges.




              © 2009 Cengage - Wadsworth
Digestion
• Anatomy of the Digestive Tract – The
  gastrointestinal (GI) tract is the flexible
  muscular tube from mouth to anus. The
  lumen is the inner space of the tract.
   The mouth is the beginning of the digestive system.
    Digestion in the mouth involves mastication
    (chewing), the stimulation of taste buds, and
    swallowing. The epiglottis closes to prevent food
    from entering the pharynx. After swallowing the food
    is called a bolus.
   The esophagus is the tube that leads the bolus to
    the stomach. There is a sphincter at the upper and
    lower (also known as the cardiac sphincter) ends of
    the esophagus.

                   © 2009 Cengage - Wadsworth
Digestion
• Anatomy of the Digestive Tract
   The stomach adds juices and grinds the
    bolus to a semiliquid mass called chyme.
    The pyloric sphincter regulates the flow of
    partially digested food into the small
    intestine.
   The small intestine receives digestive juices
    from the gallbladder and the pancreas. The
    three segments of the small intestine are
    the duodenum, the jejunum and the ileum.
   The large intestine (colon) begins at the
    ileocecal valve and ends at the rectum and
    anus. The chyme passes by the opening of
    the appendix.
                 © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Digestion
• The Muscular Action of Digestion – under
  autonomic control
   Peristalsis pushes the digestive contents
    along.
   Stomach action involves circular,
    longitudinal, and diagonal muscles.
   Segmentation is contractions by circular
    muscles that contract and squeeze contents
    to promote mixing with digestive juices.
   Sphincter contractions open and close
    passageways. This prevents reflux and
    controls the passage of contents.

                © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Digestion
• The Secretions of Digestion
   Includes digestive enzymes that act as catalysts in
    hydrolysis reactions
   Saliva from the salivary glands moistens foods
   Gastric juice from the gastric glands includes
    hydrochloric acid. The goblet cells of the stomach
    wall secrete mucus to protect the walls of the
    stomach from the high acidity levels that are
    measured by pH units.
   Pancreatic juice contains intestinal enzymes
    (carbohydrase, lipase, protease) and bicarbonate.
   Bile is produced by the liver, stored in the gall
    bladder, and acts as an emulsifier to suspend fat.



                    © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Digestion

• The Final Stage
  Energy-yielding nutrients are
   disassembled for absorption.
  Vitamins, minerals and water can be
   absorbed.
  Undigested residues, including some
   fibers, continue through the digestive
   tract and form stool.
  Recycling of usable materials

               © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Absorption

• The enormous surface area of the
  small intestine facilitates nutrient
  absorption.
• Nutrients can be absorbed through
  simple diffusion, facilitated diffusion,
  or active transport.




                © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Absorption
• Anatomy of the Absorptive System
   Villi are the fingerlike projections within the
    folds of the small intestine that move in a
    wave-like pattern to trap nutrients.
   Microvilli are the microscopic hairlike
    projections on each villi.
   Crypts are the tubular glands that lie
    between the intestinal villi.
   Goblet cells are located between the villi
    and secrete a protective thick mucus.


                  © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Absorption
• A Closer Look at the Intestinal Cells
   Specialization of the cells to absorb different
    nutrients
   “Food combining” which emphasizes
    separating food for digestive purposes is a
    myth.
   Preparing Nutrients for Transport
     • Water-soluble nutrients and small products of fat
       digestion are released to the bloodstream.
     • Fat-soluble vitamins and larger fats form
       chylomicrons and are released to the lymphatic
       system.


                   © 2009 Cengage - Wadsworth
The Circulatory System

• Water-soluble nutrients and small
  fats are routed to the liver before
  being transported to the cells.
• Fat-soluble nutrients, entering from
  the lymph, bypass the liver at first
  and eventually enter the vascular
  system.



              © 2009 Cengage - Wadsworth
The Circulatory System

• The vascular system consists of
  arteries, capillaries and veins.
  The hepatic portal vein directs blood
   from the GI tract to the liver.
  The hepatic vein takes blood from the
   liver to the heart.
  The liver protects against toxic
   substances.


              © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
The Circulatory System
• The lymphatic system consists of one-way
  vessels to transport fluid.
   Lymph is a clear, yellowish fluid without red
    blood cells or platelets that moves through
    the body by muscle contractions.
   The thoracic duct is the lymph’s route to the
    heart.
   The subclavian vein provides a return of
    lymph to the vascular system.
   Lacteals are the lymphatic vessels of the
    intestine that absorb nutrients and pass
    them to the lymphatic system.

                 © 2009 Cengage - Wadsworth
The Health and Regulation
     of the GI Tract
• The principle of homeostasis is
  important in the functioning of the
  digestive and absorptive systems.
• The body’s hormonal and nervous
  control systems keep conditions
  normal.




              © 2009 Cengage - Wadsworth
The Health and Regulation
     of the GI Tract
• Gastrointestinal Bacteria
  A healthy GI tract has many different
   non-disease-causing bacteria known
   as flora or microflora.
  Probiotics are bacteria found in the GI
   tract that can be beneficial to health.
   An example is the bacteria found in
   yogurt.
  Prebiotics are foods that are used as
   food by intestinal bacteria.

               © 2009 Cengage - Wadsworth
The Health and Regulation
     of the GI Tract
• Gastrointestinal Hormones and Nerve
  Pathways
  Hormones act as messengers, and
   those involved in the GI tract are
   known as enterogastrones.
  Gastrin is secreted by the stomach.
  Pyloric sphincter
  Secretin is secreted by the
   duodenum.

              © 2009 Cengage - Wadsworth
The Health and Regulation
     of the GI Tract
• Gastrointestinal Hormones and Nerve
  Pathways
   Pancreatic secretions change based on the
    content of the diet.
   The pancreas is protected against enzymes
    by creating enzyme precursors called
    proenzymes or zymogen.
   Cholecystokinin targets the gall bladder.
   Motility slows for foods that take longer to
    be digested.


                 © 2009 Cengage - Wadsworth
The Health and Regulation
     of the GI Tract
• The System at Its Best
  A healthy digestive tract is essential.
  Balance, moderation, variety and
   adequacy of meals are important.




               © 2009 Cengage - Wadsworth
Common Digestive
   Problems




     © 2009 Cengage - Wadsworth
Choking
• Food becomes lodged in the trachea.
• The larnyx cannot make sounds.
• The Heimlich maneuver may need to be
  used.
• Strategies
   Small bites
   Chew thoroughly.
   Don’t talk or laugh with food in the mouth.
   Don’t eat when breathing hard.


                 © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Vomiting

• Body’s adaptive mechanism
• Dehydration is a concern.
• May be self-induced as in eating
  disorders




              © 2009 Cengage - Wadsworth
Diarrhea

• Frequent, loose, watery stools
• Irritable bowel syndrome or colitis is
  one of the common GI disorders.
• Strategies
  Rest
  Drink fluids
  Medical help is needed if it persists.



               © 2009 Cengage - Wadsworth
Constipation
• Defecation habits are different among
  people.
• Many causes are possible.
• Hemorrhoids may be a problem.
• Diverticulosis is a condition in which the
  intestinal walls weaken and bulge. The
  bulging pockets are called diverticula.
  Diverticulitis is a worsened condition and
  requires intervention.
• Use of laxatives, enemas and mineral oil
  may not be necessary with lifestyle
  changes.
                 © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Constipation
• Colonic irrigation is the internal washing of
  the large intestine and can be hazardous.
• Strategies
   High-fiber diet
   Increased fluids
   Exercise regularly.
   Respond quickly to the urge to defecate.




                 © 2009 Cengage - Wadsworth
Belching and Gas

• Strategies
  Eat slowly.
  Chew thoroughly.
  Relax while eating.
  Watch bothersome foods.
• Hiccups are triggered by eating or
  drinking too fast.



               © 2009 Cengage - Wadsworth
Heartburn and
      “Acid Indigestion”
• Gastroesophageal reflux is the
  backward flow of stomach contents
  into the esophagus.
• Antacids and acid controllers may
  help indigestion.




             © 2009 Cengage - Wadsworth
© 2009 Cengage - Wadsworth
Heartburn and
       “Acid Indigestion”
• Strategies
   Small meals
   Liquids between meals
   Sit up while eating.
   Wait 1 hour after eating before lying down.
   Wait 2 hours after eating before exercising.
   Refrain from tight-fitting clothing.
   Avoid bothersome foods.
   Refrain from tobacco use.
   Lose weight if overweight.


                 © 2009 Cengage - Wadsworth
Ulcers
• Peptic ulcers can be gastric or
  duodenal.
• Strategies
  Take prescribed medicine.
  Avoid caffeine- and alcohol-containing
   foods.
  Minimize aspirin and ibuprofen use.
  No smoking.



               © 2009 Cengage - Wadsworth

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Chapter 3 NUTR

  • 1. Chapter 3 Digestion, Absorption, and Transport © 2009 Cengage - Wadsworth
  • 2. Digestion • Digestion is the process of breaking down foods into nutrients to prepare for absorption while overcoming 7 challenges. © 2009 Cengage - Wadsworth
  • 3. Digestion • Anatomy of the Digestive Tract – The gastrointestinal (GI) tract is the flexible muscular tube from mouth to anus. The lumen is the inner space of the tract.  The mouth is the beginning of the digestive system. Digestion in the mouth involves mastication (chewing), the stimulation of taste buds, and swallowing. The epiglottis closes to prevent food from entering the pharynx. After swallowing the food is called a bolus.  The esophagus is the tube that leads the bolus to the stomach. There is a sphincter at the upper and lower (also known as the cardiac sphincter) ends of the esophagus. © 2009 Cengage - Wadsworth
  • 4. Digestion • Anatomy of the Digestive Tract  The stomach adds juices and grinds the bolus to a semiliquid mass called chyme. The pyloric sphincter regulates the flow of partially digested food into the small intestine.  The small intestine receives digestive juices from the gallbladder and the pancreas. The three segments of the small intestine are the duodenum, the jejunum and the ileum.  The large intestine (colon) begins at the ileocecal valve and ends at the rectum and anus. The chyme passes by the opening of the appendix. © 2009 Cengage - Wadsworth
  • 5. © 2009 Cengage - Wadsworth
  • 6. Digestion • The Muscular Action of Digestion – under autonomic control  Peristalsis pushes the digestive contents along.  Stomach action involves circular, longitudinal, and diagonal muscles.  Segmentation is contractions by circular muscles that contract and squeeze contents to promote mixing with digestive juices.  Sphincter contractions open and close passageways. This prevents reflux and controls the passage of contents. © 2009 Cengage - Wadsworth
  • 7. © 2009 Cengage - Wadsworth
  • 8. © 2009 Cengage - Wadsworth
  • 9. © 2009 Cengage - Wadsworth
  • 10. Digestion • The Secretions of Digestion  Includes digestive enzymes that act as catalysts in hydrolysis reactions  Saliva from the salivary glands moistens foods  Gastric juice from the gastric glands includes hydrochloric acid. The goblet cells of the stomach wall secrete mucus to protect the walls of the stomach from the high acidity levels that are measured by pH units.  Pancreatic juice contains intestinal enzymes (carbohydrase, lipase, protease) and bicarbonate.  Bile is produced by the liver, stored in the gall bladder, and acts as an emulsifier to suspend fat. © 2009 Cengage - Wadsworth
  • 11. © 2009 Cengage - Wadsworth
  • 12. © 2009 Cengage - Wadsworth
  • 13. Digestion • The Final Stage Energy-yielding nutrients are disassembled for absorption. Vitamins, minerals and water can be absorbed. Undigested residues, including some fibers, continue through the digestive tract and form stool. Recycling of usable materials © 2009 Cengage - Wadsworth
  • 14. © 2009 Cengage - Wadsworth
  • 15. © 2009 Cengage - Wadsworth
  • 16. Absorption • The enormous surface area of the small intestine facilitates nutrient absorption. • Nutrients can be absorbed through simple diffusion, facilitated diffusion, or active transport. © 2009 Cengage - Wadsworth
  • 17. © 2009 Cengage - Wadsworth
  • 18. Absorption • Anatomy of the Absorptive System  Villi are the fingerlike projections within the folds of the small intestine that move in a wave-like pattern to trap nutrients.  Microvilli are the microscopic hairlike projections on each villi.  Crypts are the tubular glands that lie between the intestinal villi.  Goblet cells are located between the villi and secrete a protective thick mucus. © 2009 Cengage - Wadsworth
  • 19. © 2009 Cengage - Wadsworth
  • 20. Absorption • A Closer Look at the Intestinal Cells  Specialization of the cells to absorb different nutrients  “Food combining” which emphasizes separating food for digestive purposes is a myth.  Preparing Nutrients for Transport • Water-soluble nutrients and small products of fat digestion are released to the bloodstream. • Fat-soluble vitamins and larger fats form chylomicrons and are released to the lymphatic system. © 2009 Cengage - Wadsworth
  • 21. The Circulatory System • Water-soluble nutrients and small fats are routed to the liver before being transported to the cells. • Fat-soluble nutrients, entering from the lymph, bypass the liver at first and eventually enter the vascular system. © 2009 Cengage - Wadsworth
  • 22. The Circulatory System • The vascular system consists of arteries, capillaries and veins. The hepatic portal vein directs blood from the GI tract to the liver. The hepatic vein takes blood from the liver to the heart. The liver protects against toxic substances. © 2009 Cengage - Wadsworth
  • 23. © 2009 Cengage - Wadsworth
  • 24. © 2009 Cengage - Wadsworth
  • 25. The Circulatory System • The lymphatic system consists of one-way vessels to transport fluid.  Lymph is a clear, yellowish fluid without red blood cells or platelets that moves through the body by muscle contractions.  The thoracic duct is the lymph’s route to the heart.  The subclavian vein provides a return of lymph to the vascular system.  Lacteals are the lymphatic vessels of the intestine that absorb nutrients and pass them to the lymphatic system. © 2009 Cengage - Wadsworth
  • 26. The Health and Regulation of the GI Tract • The principle of homeostasis is important in the functioning of the digestive and absorptive systems. • The body’s hormonal and nervous control systems keep conditions normal. © 2009 Cengage - Wadsworth
  • 27. The Health and Regulation of the GI Tract • Gastrointestinal Bacteria A healthy GI tract has many different non-disease-causing bacteria known as flora or microflora. Probiotics are bacteria found in the GI tract that can be beneficial to health. An example is the bacteria found in yogurt. Prebiotics are foods that are used as food by intestinal bacteria. © 2009 Cengage - Wadsworth
  • 28. The Health and Regulation of the GI Tract • Gastrointestinal Hormones and Nerve Pathways Hormones act as messengers, and those involved in the GI tract are known as enterogastrones. Gastrin is secreted by the stomach. Pyloric sphincter Secretin is secreted by the duodenum. © 2009 Cengage - Wadsworth
  • 29. The Health and Regulation of the GI Tract • Gastrointestinal Hormones and Nerve Pathways  Pancreatic secretions change based on the content of the diet.  The pancreas is protected against enzymes by creating enzyme precursors called proenzymes or zymogen.  Cholecystokinin targets the gall bladder.  Motility slows for foods that take longer to be digested. © 2009 Cengage - Wadsworth
  • 30. The Health and Regulation of the GI Tract • The System at Its Best A healthy digestive tract is essential. Balance, moderation, variety and adequacy of meals are important. © 2009 Cengage - Wadsworth
  • 31. Common Digestive Problems © 2009 Cengage - Wadsworth
  • 32. Choking • Food becomes lodged in the trachea. • The larnyx cannot make sounds. • The Heimlich maneuver may need to be used. • Strategies  Small bites  Chew thoroughly.  Don’t talk or laugh with food in the mouth.  Don’t eat when breathing hard. © 2009 Cengage - Wadsworth
  • 33. © 2009 Cengage - Wadsworth
  • 34. © 2009 Cengage - Wadsworth
  • 35. Vomiting • Body’s adaptive mechanism • Dehydration is a concern. • May be self-induced as in eating disorders © 2009 Cengage - Wadsworth
  • 36. Diarrhea • Frequent, loose, watery stools • Irritable bowel syndrome or colitis is one of the common GI disorders. • Strategies Rest Drink fluids Medical help is needed if it persists. © 2009 Cengage - Wadsworth
  • 37. Constipation • Defecation habits are different among people. • Many causes are possible. • Hemorrhoids may be a problem. • Diverticulosis is a condition in which the intestinal walls weaken and bulge. The bulging pockets are called diverticula. Diverticulitis is a worsened condition and requires intervention. • Use of laxatives, enemas and mineral oil may not be necessary with lifestyle changes. © 2009 Cengage - Wadsworth
  • 38. © 2009 Cengage - Wadsworth
  • 39. Constipation • Colonic irrigation is the internal washing of the large intestine and can be hazardous. • Strategies  High-fiber diet  Increased fluids  Exercise regularly.  Respond quickly to the urge to defecate. © 2009 Cengage - Wadsworth
  • 40. Belching and Gas • Strategies Eat slowly. Chew thoroughly. Relax while eating. Watch bothersome foods. • Hiccups are triggered by eating or drinking too fast. © 2009 Cengage - Wadsworth
  • 41. Heartburn and “Acid Indigestion” • Gastroesophageal reflux is the backward flow of stomach contents into the esophagus. • Antacids and acid controllers may help indigestion. © 2009 Cengage - Wadsworth
  • 42. © 2009 Cengage - Wadsworth
  • 43. Heartburn and “Acid Indigestion” • Strategies  Small meals  Liquids between meals  Sit up while eating.  Wait 1 hour after eating before lying down.  Wait 2 hours after eating before exercising.  Refrain from tight-fitting clothing.  Avoid bothersome foods.  Refrain from tobacco use.  Lose weight if overweight. © 2009 Cengage - Wadsworth
  • 44. Ulcers • Peptic ulcers can be gastric or duodenal. • Strategies Take prescribed medicine. Avoid caffeine- and alcohol-containing foods. Minimize aspirin and ibuprofen use. No smoking. © 2009 Cengage - Wadsworth