Robert Hooke first observed cells in 1665 using a microscope to look at cork. Anton van Leeuwenhoek later observed the first living cells in pond water in 1673. In the 1800s, scientists including Matthias Schleiden, Theodor Schwann, and Rudolph Virchow developed the cell theory, which states that all living things are composed of cells, cells are the basic units of structure and function, and cells only come from preexisting cells. Cells later evolved to be more specialized and form multicellular organisms through the development of tissues, organs, and organ systems.