This document discusses experimental design for measuring the effectiveness of advertising. It presents several ideas for experiments, including measuring total store sales after advertising campaigns, comparing online purchases of those who saw an ad to those who did not, and using randomized controlled experiments. It notes challenges like defining good controls and issues of external validity. Specific case studies discussed include measuring ad wear-out using a natural experiment with Yahoo ads and using Yelp rating rounding as a natural experiment to measure ratings' impact on restaurant revenue.