To divide a number by a decimal, we can multiply both the dividend and divisor by powers of 10 to clear the decimal. This is done by moving the decimal point to the right in both numbers the same number of places. Doing so does not change the value of the division. The document provides an example of dividing 37.5 by 1.25 by first multiplying both numbers by 10 and 100 to convert it to a division with whole number values.