The document provides information for the structural design of an expansion to the Ramos Vaccine Laboratories in Managua, Nicaragua. The expansion will include adding floors and increasing the building footprint. Key points:
- The site is located 6km northwest of Managua and experiences high seismic activity.
- The structural system will include reinforced concrete shear walls, steel columns, steel beams, and concrete slabs. Shear walls along the perimeter will resist most seismic loads.
- A raft foundation is proposed due to loose soils with a safe bearing capacity of 170kN/m2 at a depth of 2m.
- Design will follow international standards including Eurocodes and consider loads from gravity, wind,