The research paper focuses on improving the diagnosis of heart diseases using multi-slice CT angiogram images through advanced digital image processing techniques, specifically exploring linear and non-linear classifiers such as support vector machines (SVM) and radial basis function (RBF) neural networks. The study emphasizes the importance of accurate heart segmentation and feature extraction for the automated detection of diseases, highlighting that the proposed RBF neural network approach outperforms existing methodologies in terms of efficiency and accuracy. The methodology includes data processing, segmentation using k-means++, and evaluation of various machine learning algorithms on diverse datasets to enhance classification performance.