Endnote is a reference management software that allows users to import references from databases like PubMed and Web of Science, manually add references, insert citations into a Word document, and automatically generate bibliographies in various formats. Key features include storing references in a searchable database, eliminating errors by recognizing duplicate references, and formatting citations and bibliographies with just a few clicks. The tutorial covered how to install Endnote, import references from various sources, add references manually, insert citations into a Word doc, and format the bibliography.