The document proposes three strategies for approximating reduce-and-rank (RnR) computations to improve energy efficiency: 1) interleaving partial reductions with ranking to identify computations with low impact that can be approximated, 2) exploiting input similarity to approximate related computations, and 3) reordering reference vectors to prioritize critical vectors. It develops a runtime framework to dynamically tune these strategies based on a quality metric to minimize energy while meeting quality targets. The strategies were evaluated via hardware implementations of six RnR applications in 45-nm technology using Modelsim and Xilinx ISE for analysis.