This document provides guidance on using Twitter to engage stakeholders, inform audiences, and promote the UK Cochrane Centre. It outlines best practices for tweeting, including keeping tweets concise at 140 characters, using hashtags to make tweets searchable, and building a following by retweeting others and recommending relevant accounts. The document also discusses timing tweets for maximum visibility and engaging audiences through tweet chats and live tweeting conferences. Monitoring analytics can show the value of an active Twitter presence through a growing following and positive engagement.