PyCon APAC 2015 discusses the Global Interpreter Lock (GIL) in CPython and ways to work around it to achieve higher performance on multi-processor systems. It provides examples of using multiprocessing, pp (Parallel Python), and releasing the GIL using C extensions to allow concurrent execution across multiple CPU cores. Releasing the GIL allows taking advantage of additional CPUs for processor-intensive tasks, while multiprocessing and pp allow running I/O-bound tasks in parallel across multiple processes to improve throughput.