HIV self-testing increases HIV testing frequency among high risk MSM: a randomized controlled trial
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HIV self-testing increased the frequency of HIV testing among high-risk MSM compared to standard testing. Those randomized to HIV self-testing had a mean of 5.3 HIV tests over 15 months, significantly more than the 3.6 tests in the standard care group. While HIV self-testing increased testing rates, it did not negatively impact markers of HIV risk acquisition or result in more sexually transmitted infections. The researchers concluded that HIV self-testing programs can raise HIV status awareness without affecting risk, but more research is still needed.
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HIV self-testing increases HIV testing frequency among high risk MSM: a randomized controlled trial
- 1. HIV Self-Testing Increases HIV Testing Frequency among High Risk MSM: A Randomized Controlled Trial 230 HIV-negative MSM at high risk for HIV acquisition in Seattle randomized for 15 months to: HIV self-testing (HIVST): access to self-tests at no cost Standard Testing: testing as usual Aim 1: Compare number of HIV tests during follow-up among men randomized to HIVST vs. standard testing Aim 2: Determine whether HIVST is non-inferior to standard testing with respect to markers for risk of HIV acquisition HIV self-testing = OraQuick on oral fluids, written instructions & counseling, kits available upon request by mail/pick-up All participants recommended to test quarterly & offered reminders to test per standard of care David A. Katz, Matthew R. Golden, James P. Hughes, Carey Farquhar, Joanne D. Stekler
- 2. Access to HIVST increased HIV testing 0% 5% 10% 15% 20% 25% 30% 0 2 4 6 8 10 12 14 16 18 20 Self-reported number of HIV tests during follow-up Self-testing (N=98) Control (N=99) Arm Number of HIV tests Mean (95% CI) ≥1 HIV test N (%) ≥Quarterly testing N (%) Self-testing 5.3 (4.7-6.0) 96 (98%) 74 (76%) Control 3.6 (3.2-4.0) 92 (93%) 53 (54%) P<0.0001 P=0.17 P=0.001
- 3. Effect on HIV risk & Conclusions 5% 21% 29% 12% 22% 24% 0% 5% 10% 15% 20% 25% 30% 35% STI diagnosis 15 months Non-concordant CAI 9 months Non-concordant CAI 15 months Self-testing Control 1 1 1 1 0 1 2 3 Self-testing Control Self-testing Control Median ( ) and interquartile range ( | ) of male condomless anal intercourse (CAI) partners reported in last 3 months 9 months 15 months Risk difference -6.8% (-16-1.6%) Odds ratio 1.08 (0.61-1.90) Incidence rate ratio 0.92 (0.64-1.33) Conclusions HIV self-testing programs may ↑ awareness of HIV status without affecting HIV risk Research necessary to: Determine effect of self-testing in other settings/populations Ensure timely linkage to HIV care Identify cost-effective methods for implementation Poster MOPDC0103; Funded by NIMH (R01 MH086360); Clinicaltrials.gov NCT01161446