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Hyperthyroidism
Rangen Ashna Ghafur
Outline
• Introduction
• Thyroid gland overview
• Causes of hyperthyroidism
• Symptoms & signs
• Diagnosis
• Main complications of hyperthyroidism
• Treatment & options
• Lifestyle & monitoring
• Conclusion
• Reference
Introduction
• Ever feel like your body’s stuck on fast-forward?
• You eat like a horse but lose weight like magic? 🐎
• Your heart’s racing, hands are shaky, and you're sweating like
it’s summer all year? ☀💦
• It might not be stress or too much coffee… it could be
hyperthyroidism!
• A condition where your thyroid gland gets a little too
energetic.
Thyroid gland overview
• Anatomy & Location
• Small, butterfly-shaped gland located in the front of the neck, just
below the Adam’s apple.
• Wrapped around the trachea (windpipe), with two lobes connected by
a thin piece called the isthmus.
• Hormones Produced
• Thyroxine (T4) – contains 4 iodine atoms; most abundant thyroid hormone.
• Triiodothyronine (T3) – contains 3 iodine atoms; more active form of thyroid
hormone.
• Calcitonin – helps regulate calcium levels in the blood by inhibiting bone
breakdown.
• Regulation
• Controlled by the hypothalamus-pituitary-thyroid (HPT) axis:
• Hypothalamus releases TRH (thyrotropin-releasing hormone).
• TRH signals the pituitary gland to release TSH (thyroid-
stimulating hormone).
• TSH stimulates the thyroid gland to produce and release T3
and T4.
• Negative feedback loop: High levels of T3 and T4 signal the
brain to reduce TRH and TSH production.
Causes of hyperthyroidism
• Graves' Disease
• An autoimmune disorder where the immune system stimulates the thyroid to
produce too much hormone. It's the most common cause of hyperthyroidism.
• Overactive Thyroid Nodules
• Also known as toxic adenoma or toxic multinodular goiter, these are
noncancerous lumps in the thyroid that produce excess hormones.
• Thyroiditis
• Inflammation of the thyroid gland, which can cause stored hormones to leak
into the bloodstream, leading to temporary hyperthyroidism.
Symptoms & signs
• Rapid heartbeat or palpitations.
• Sensitivity to heat / excessive sweating.
• Unexplained weight loss.
• Anxiety, irritability, or nervousness.
• Difficulty sleeping (insomnia).
• Muscle weakness or tremors.
• Eye problems (like bulging eyes in Graves’ disease).
• Irregular or light menstrual periods.
Diagnosis
• Physical Examination
• Your doctor checks for signs like a rapid or irregular heartbeat, an enlarged
thyroid (goiter), or bulging eyes (common in Graves’ disease).
• Blood Tests
• Measures levels of:
• Thyroid-Stimulating Hormone (TSH): Typically low in hyperthyroidism.
• T3 and T4: Usually elevated.
• Thyroid-Stimulating Immunoglobulins (TSI): May be present in
Graves’ disease.
• Radioactive Iodine Uptake Test
• Involves swallowing a small amount of radioactive iodine.
• Measures how much iodine the thyroid absorbs:
• High uptake suggests Graves’ disease.
• Low uptake may indicate thyroiditis.
• Thyroid Ultrasound
• Uses sound waves to create images of the thyroid.
• Helps identify nodules or inflammation.
Main complications of hyperthyroidism
• Heart Problems
• Irregular heartbeat (atrial fibrillation) and heart failure.
•
Thyroid Eye Disease
• Bulging eyes, double vision, irritation—common in Graves’ disease.
• Thyroid Storm (Rare but serious)
• Sudden, severe symptoms like high fever, rapid heartbeat, and
confusion—life-threatening.
• Osteoporosis
• Weakened bones due to long-term excess thyroid
hormones.
• Pregnancy Complications
• Can lead to miscarriage, premature birth, or pre-eclampsia
if untreated.
Treatment options
• Anti-thyroid drugs — reduce hormone production.
• Radioactive iodine — destroys overactive thyroid cells.
• Surgery — removes part or all of the thyroid gland.
Lifestyle & monitoring
• Eat a balanced diet – Avoid too much iodine (like seaweed).
• Manage stress – Relaxation techniques can ease symptoms.
• Get enough sleep – Helps with fatigue and mood swings.
• Avoid caffeine – It can worsen heart palpitations and anxiety.
• Regular blood tests – To monitor thyroid hormone levels.
• Take meds as prescribed – Don’t skip doses and follow up
with your doctor.
Conclusion
• Hyperthyroidism is manageable with proper treatment.
• Early diagnosis and regular monitoring are essential.
• Treatment options are effective and vary based on each
case.
• Healthy lifestyle choices support better symptom control.
• With care, patients can live full and healthy lives.
Reference
• https://
my.clevelandclinic.org/health/diseases/14129-hyperth
yroidism
• https://
www.msdmanuals.com/home/hormonal-and-metabol
ic-disorders/thyroid-gland-disorders/overview-of-the-t
hyroid-gland
• https://
www.mayoclinic.org/diseases-conditions/hyperthyroid
ism/symptoms-causes/syc-20373659
• https://www.nhs.uk/conditions/overactive-thyroid-hyp
erthyroidism/symptoms
/

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Hyperthyroidism: What You Need to Know..

  • 2. Outline • Introduction • Thyroid gland overview • Causes of hyperthyroidism • Symptoms & signs • Diagnosis • Main complications of hyperthyroidism • Treatment & options • Lifestyle & monitoring • Conclusion • Reference
  • 3. Introduction • Ever feel like your body’s stuck on fast-forward? • You eat like a horse but lose weight like magic? 🐎 • Your heart’s racing, hands are shaky, and you're sweating like it’s summer all year? ☀💦 • It might not be stress or too much coffee… it could be hyperthyroidism! • A condition where your thyroid gland gets a little too energetic.
  • 5. • Anatomy & Location • Small, butterfly-shaped gland located in the front of the neck, just below the Adam’s apple. • Wrapped around the trachea (windpipe), with two lobes connected by a thin piece called the isthmus. • Hormones Produced • Thyroxine (T4) – contains 4 iodine atoms; most abundant thyroid hormone. • Triiodothyronine (T3) – contains 3 iodine atoms; more active form of thyroid hormone. • Calcitonin – helps regulate calcium levels in the blood by inhibiting bone breakdown.
  • 6. • Regulation • Controlled by the hypothalamus-pituitary-thyroid (HPT) axis: • Hypothalamus releases TRH (thyrotropin-releasing hormone). • TRH signals the pituitary gland to release TSH (thyroid- stimulating hormone). • TSH stimulates the thyroid gland to produce and release T3 and T4. • Negative feedback loop: High levels of T3 and T4 signal the brain to reduce TRH and TSH production.
  • 7. Causes of hyperthyroidism • Graves' Disease • An autoimmune disorder where the immune system stimulates the thyroid to produce too much hormone. It's the most common cause of hyperthyroidism. • Overactive Thyroid Nodules • Also known as toxic adenoma or toxic multinodular goiter, these are noncancerous lumps in the thyroid that produce excess hormones. • Thyroiditis • Inflammation of the thyroid gland, which can cause stored hormones to leak into the bloodstream, leading to temporary hyperthyroidism.
  • 9. • Rapid heartbeat or palpitations. • Sensitivity to heat / excessive sweating. • Unexplained weight loss. • Anxiety, irritability, or nervousness. • Difficulty sleeping (insomnia). • Muscle weakness or tremors. • Eye problems (like bulging eyes in Graves’ disease). • Irregular or light menstrual periods.
  • 11. • Physical Examination • Your doctor checks for signs like a rapid or irregular heartbeat, an enlarged thyroid (goiter), or bulging eyes (common in Graves’ disease). • Blood Tests • Measures levels of: • Thyroid-Stimulating Hormone (TSH): Typically low in hyperthyroidism. • T3 and T4: Usually elevated. • Thyroid-Stimulating Immunoglobulins (TSI): May be present in Graves’ disease.
  • 12. • Radioactive Iodine Uptake Test • Involves swallowing a small amount of radioactive iodine. • Measures how much iodine the thyroid absorbs: • High uptake suggests Graves’ disease. • Low uptake may indicate thyroiditis. • Thyroid Ultrasound • Uses sound waves to create images of the thyroid. • Helps identify nodules or inflammation.
  • 13. Main complications of hyperthyroidism • Heart Problems • Irregular heartbeat (atrial fibrillation) and heart failure. • Thyroid Eye Disease • Bulging eyes, double vision, irritation—common in Graves’ disease. • Thyroid Storm (Rare but serious) • Sudden, severe symptoms like high fever, rapid heartbeat, and confusion—life-threatening.
  • 14. • Osteoporosis • Weakened bones due to long-term excess thyroid hormones. • Pregnancy Complications • Can lead to miscarriage, premature birth, or pre-eclampsia if untreated.
  • 16. • Anti-thyroid drugs — reduce hormone production. • Radioactive iodine — destroys overactive thyroid cells. • Surgery — removes part or all of the thyroid gland.
  • 18. • Eat a balanced diet – Avoid too much iodine (like seaweed). • Manage stress – Relaxation techniques can ease symptoms. • Get enough sleep – Helps with fatigue and mood swings. • Avoid caffeine – It can worsen heart palpitations and anxiety. • Regular blood tests – To monitor thyroid hormone levels. • Take meds as prescribed – Don’t skip doses and follow up with your doctor.
  • 19. Conclusion • Hyperthyroidism is manageable with proper treatment. • Early diagnosis and regular monitoring are essential. • Treatment options are effective and vary based on each case. • Healthy lifestyle choices support better symptom control. • With care, patients can live full and healthy lives.
  • 20. Reference • https:// my.clevelandclinic.org/health/diseases/14129-hyperth yroidism • https:// www.msdmanuals.com/home/hormonal-and-metabol ic-disorders/thyroid-gland-disorders/overview-of-the-t hyroid-gland • https:// www.mayoclinic.org/diseases-conditions/hyperthyroid ism/symptoms-causes/syc-20373659 • https://www.nhs.uk/conditions/overactive-thyroid-hyp erthyroidism/symptoms /