The document discusses advanced networking capabilities and applications for research and education both currently and in the future. Today, networks provide megabit bandwidth and IP services focused on campuses, while coordination across networks is loose. Tomorrow, gigabit bandwidth, IP and dynamic circuit services will have inter-domain middleware and high coordination across networks. Today's applications include videoconferencing and sharing small data sets, while remote instruments have limited access. Future applications will support uncompressed HD video, sharing terabyte data sets globally, and routine access to remote instruments. A variety of research applications are discussed that benefit from high-speed networks including distributed computing, telemedicine, astronomy, and tele-immersion.