This document provides an introduction and overview of HAZOP (Hazard and Operability) analysis. It discusses that HAZOP is a systematic approach to identifying hazards and deviations from design parameters like flow, temperature, and pressure. The objectives of HAZOP are to investigate potential deviations from design intent and their causes, consequences, safeguards, and recommended actions. An example HAZOP analysis is provided to illustrate the methodology. Key advantages of HAZOP include improving safety and identifying imaginative risks and operability issues. Recent major accidents in the pharmaceutical industry are also briefly mentioned.