This document summarizes research on using computational fluid dynamics (CFD) simulations to analyze heat transfer and friction factors for turbulent flow of titanium dioxide, iron oxide, and silicon dioxide nanofluid in semi-circle corrugated channels. The simulations were conducted at Reynolds numbers of 10,000-30,000, nanoparticle volume fractions of 0-6%, and constant heat flux conditions. Results showed that the Nusselt number, a measure of heat transfer, increased with higher nanoparticle volume fraction and Reynolds number. Maximum Nusselt number enhancement of 2.07 was found at a Reynolds number of 30,000 and volume fraction of 6%.