JavaScript is the programming language of the web and allows for dynamic interactions on HTML pages. It can access and modify HTML elements using the DOM and be used to build interactive experiences directly in web pages. JavaScript code is executed by web browsers and common uses include modifying content, styling elements, handling events, and validating user input. It is an interpreted language that is case-sensitive, supports data types like strings, numbers, booleans, and objects, and uses functions to organize code into reusable blocks.