JISC has invested over £200 million in UK universities over the past decade to create a collaborative innovation network that has driven new approaches to research. It has developed digital infrastructure including the JANET network, federated access management, and national data centers. Looking ahead, JISC is pushing boundaries through initiatives like building a cloud for UK higher education and supporting open science practices. It provides digital resources to researchers through national licensing agreements and repositories, and supports research processes through text mining tools and research data management.