KnockoutJS is a JavaScript library that provides declarative bindings between a data model and UI. It exposes the MVVM pattern, separating model, view, and view model concerns. Two-way data binding automatically synchronizes data between the model and view. Observables notify of changes and detect dependencies, enabling two-way binding between UI elements and the JavaScript view model. KnockoutJS is lightweight, fully documented, and suitable for building small to medium single-page applications.