The document discusses biosafety and biosecurity. Biosafety involves containment principles, technologies, and practices to prevent exposure to biological hazards and their accidental release. Biosecurity protects pathogens from threats. A hazard is something that can cause harm, while a threat is a person intending to cause harm. Risk is the likelihood of an undesirable event occurring, based on a hazard or threat. Laboratory biosafety focuses on preventing unintentional exposure or release of pathogens. Laboratory biosecurity protects and controls valuable biological materials to prevent unauthorized access. Common causes of laboratory acquired infections include equipment failure and human error.