This document discusses assessing seismic risk across populations of unreinforced masonry buildings. A methodology is presented that involves developing an inventory of buildings, estimating building-specific damage from ground motions, and aggregating to determine total regional loss and risk. Sensitivity investigations are proposed to examine how regional risk estimates depend on regional and building-specific parameters like population size, ground motion intensity, number of stories, floor area, and others. Field survey data from various cities is used to establish distributions for modeling building populations.