This document outlines UNESCO's process for developing a Recommendation on Open Science through a global consensus-building effort. It notes that 193 UNESCO member states tasked UNESCO with creating an international standard-setting instrument on Open Science in the form of a Recommendation. UNESCO will rely on an inclusive consultation process involving countries and stakeholders to define principles for Open Science and measures on open access and data to bring citizens closer to science and promote equitable science production worldwide. The Recommendation is expected to be adopted by member states in 2021 after regional consultations are completed.