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Lecture Slide Presentation
by Patty Bostwick-Taylor,
Florence-Darlington Technical College
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
PART A
7
The Nervous
System
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functions of the Nervous System
 Sensory input—gathering information
 To monitor changes occurring inside and
outside the body
 Changes = stimuli
 Integration
 To process and interpret sensory input and
decide if action is needed
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functions of the Nervous System
 Motor output
 A response to integrated stimuli
 The response activates muscles or glands
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Classification
of the Nervous System
 Central nervous system (CNS)
 Brain
 Spinal cord
 Peripheral nervous system (PNS)
 Nerves outside the brain and spinal cord
 Spinal nerves
 Cranial nerves
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of
the Peripheral Nervous System
 Sensory (afferent) division
 Nerve fibers that carry information to the
central nervous system
 Motor (efferent) division
 Nerve fibers that carry impulses away from the
central nervous system
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Organization of the Nervous System
Figure 7.2
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of
the Peripheral Nervous System
 Motor (efferent) division (continued)
 Two subdivisions
 Somatic nervous system = voluntary
 Autonomic nervous system = involuntary
Nervous Tissue: Support Cells
 Support cells in the CNS are grouped together as
“neuroglia”
 Function: to support, insulate, and protect
neurons
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Astrocytes
 Abundant, star-shaped cells
 Brace neurons
 Form barrier between capillaries and neurons
 Control the chemical environment of
the brain
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Microglia
 Spiderlike phagocytes
 Dispose of debris
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Ependymal cells
 Line cavities of the brain and spinal cord
 Circulate cerebrospinal fluid
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Oligodendrocytes
 Wrap around nerve fibers in the central
nervous system
 Produce myelin sheaths
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Satellite cells
 Protect neuron cell bodies
 Schwann cells
 Form myelin sheath in the peripheral nervous
system
*Oligodendrocytes wrap
central nerves and
Schwann cells wrap
peripheral nerves.
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Neurons = nerve cells
 Cells specialized to transmit messages
 Major regions of neurons
 Cell body—nucleus and metabolic center
of the cell
 Processes—fibers that extend from the
cell body
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Cell body
 Nucleus
 Large nucleolus
 Processes outside the cell body
 Dendrites—conduct impulses toward the cell
body
 Axons—conduct impulses away from the cell
body
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
Figure 7.4
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Axons end in axonal terminals
 Axonal terminals contain vesicles with
neurotransmitters
 Axonal terminals are separated from the next
neuron by a gap
 Synaptic cleft—gap between adjacent neurons
 Synapse—junction between nerves
 http://www.youtube.com/watch?v=LT3VKAr4roo Synapse
Synaptic
Cleft
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
Figure 7.5
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Myelin sheath—whitish, fatty material covering
axons
 Schwann cells—produce myelin sheaths in jelly
roll–like fashion
 Nodes of Ranvier—gaps in myelin sheath along
the axon
 https://www.youtube.com/watch?v=G3WUJ9XaZWc saltatory
conduction
 http://www.youtube.com/watch?v=qgySDmRRzxY
 https://www.youtube.com/watch?v=i30Bv_E0qAU
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Cell Body Location
 Most neuron cell bodies are found in the central nervous system
 Gray matter—cell bodies and unmyelinated fibers
 Nuclei—clusters of cell bodies within the white matter of the
central nervous system
 Ganglia—collections of cell bodies outside the central nervous
system
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of Neurons
Figure 7.7
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of Neurons
 Interneurons (association neurons)
 Found in neural pathways in the central
nervous system
 Connect sensory and motor neurons
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Classification
Figure 7.6
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 7.8a
Structural Classification of Neurons
 Multipolar neurons—many extensions from the cell body
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Properties of Neurons
 Irritability
 Ability to respond to stimuli
 Conductivity
 Ability to transmit an impulse
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Resting neuron
 The plasma membrane at rest is polarized
 Fewer positive ions are inside the cell than
outside the cell
 Depolarization
 A stimulus depolarizes the neuron’s
membrane
 A depolarized membrane allows sodium (Na+)
to flow inside the membrane
 The exchange of ions initiates an action potential
in the neuron
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
Figure 7.9a–b
http://www.youtube.com/watch?v=YP_P6bYvEjE
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Action potential
 If the action potential (nerve impulse) starts, it
is propagated over the entire axon
 Impulses travel faster when fibers have a
myelin sheath
 http://www.youtube.com/watch?v=R0TdXkxBOkE
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
Figure 7.9c–d
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Repolarization
 Potassium ions rush out of the neuron after
sodium ions rush in, which repolarizes the
membrane
 The sodium-potassium pump, using ATP,
restores the original configuration
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
Figure 7.9e–f
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
 Impulses are able to cross the synapse to another
nerve
 Neurotransmitter is released from a nerve’s
axon terminal
 The dendrite of the next neuron has receptors
that are stimulated by the neurotransmitter
 An action potential is started in the dendrite
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Figure 7.10, step 1
Axon
terminal
Vesicles
Synaptic
cleft
Action
potential
arrives
Synapse
Axon of
transmitting
neuron
Receiving
neuron
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Figure 7.10, step 6
Neurotrans-
mitter is re-
leased into
synaptic cleft
Neurotrans-
mitter binds
to receptor
on receiving
neuron’s
membrane
Vesicle
fuses with
plasma
membrane
Synaptic cleft
Neurotransmitter
molecules
Ion channels
Receiving neuron
Transmitting neuron
Receptor
Neurotransmitter
Na+
Na+
Neurotransmitter
broken down
and released
Ion channel opens Ion channel closes

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Nervous System Notes A

  • 1. PowerPoint® Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings PART A 7 The Nervous System
  • 2. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functions of the Nervous System  Sensory input—gathering information  To monitor changes occurring inside and outside the body  Changes = stimuli  Integration  To process and interpret sensory input and decide if action is needed
  • 3. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functions of the Nervous System  Motor output  A response to integrated stimuli  The response activates muscles or glands
  • 4. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Structural Classification of the Nervous System  Central nervous system (CNS)  Brain  Spinal cord  Peripheral nervous system (PNS)  Nerves outside the brain and spinal cord  Spinal nerves  Cranial nerves
  • 5. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functional Classification of the Peripheral Nervous System  Sensory (afferent) division  Nerve fibers that carry information to the central nervous system  Motor (efferent) division  Nerve fibers that carry impulses away from the central nervous system
  • 6. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Organization of the Nervous System Figure 7.2
  • 7. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functional Classification of the Peripheral Nervous System  Motor (efferent) division (continued)  Two subdivisions  Somatic nervous system = voluntary  Autonomic nervous system = involuntary Nervous Tissue: Support Cells  Support cells in the CNS are grouped together as “neuroglia”  Function: to support, insulate, and protect neurons
  • 8. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Astrocytes  Abundant, star-shaped cells  Brace neurons  Form barrier between capillaries and neurons  Control the chemical environment of the brain
  • 9. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Microglia  Spiderlike phagocytes  Dispose of debris
  • 10. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Ependymal cells  Line cavities of the brain and spinal cord  Circulate cerebrospinal fluid
  • 11. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Oligodendrocytes  Wrap around nerve fibers in the central nervous system  Produce myelin sheaths
  • 12. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Satellite cells  Protect neuron cell bodies  Schwann cells  Form myelin sheath in the peripheral nervous system *Oligodendrocytes wrap central nerves and Schwann cells wrap peripheral nerves.
  • 13. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons  Neurons = nerve cells  Cells specialized to transmit messages  Major regions of neurons  Cell body—nucleus and metabolic center of the cell  Processes—fibers that extend from the cell body
  • 14. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons  Cell body  Nucleus  Large nucleolus  Processes outside the cell body  Dendrites—conduct impulses toward the cell body  Axons—conduct impulses away from the cell body
  • 15. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons Figure 7.4
  • 16. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons  Axons end in axonal terminals  Axonal terminals contain vesicles with neurotransmitters  Axonal terminals are separated from the next neuron by a gap  Synaptic cleft—gap between adjacent neurons  Synapse—junction between nerves  http://www.youtube.com/watch?v=LT3VKAr4roo Synapse Synaptic Cleft
  • 17. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 18. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons Figure 7.5
  • 19. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons  Myelin sheath—whitish, fatty material covering axons  Schwann cells—produce myelin sheaths in jelly roll–like fashion  Nodes of Ranvier—gaps in myelin sheath along the axon  https://www.youtube.com/watch?v=G3WUJ9XaZWc saltatory conduction  http://www.youtube.com/watch?v=qgySDmRRzxY  https://www.youtube.com/watch?v=i30Bv_E0qAU
  • 20. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 21. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Neuron Cell Body Location  Most neuron cell bodies are found in the central nervous system  Gray matter—cell bodies and unmyelinated fibers  Nuclei—clusters of cell bodies within the white matter of the central nervous system  Ganglia—collections of cell bodies outside the central nervous system
  • 22. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 23. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functional Classification of Neurons Figure 7.7
  • 24. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functional Classification of Neurons  Interneurons (association neurons)  Found in neural pathways in the central nervous system  Connect sensory and motor neurons
  • 25. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Neuron Classification Figure 7.6
  • 26. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Figure 7.8a Structural Classification of Neurons  Multipolar neurons—many extensions from the cell body
  • 27. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Functional Properties of Neurons  Irritability  Ability to respond to stimuli  Conductivity  Ability to transmit an impulse
  • 28. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
  • 29. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulses  Resting neuron  The plasma membrane at rest is polarized  Fewer positive ions are inside the cell than outside the cell  Depolarization  A stimulus depolarizes the neuron’s membrane  A depolarized membrane allows sodium (Na+) to flow inside the membrane  The exchange of ions initiates an action potential in the neuron
  • 30. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulses Figure 7.9a–b http://www.youtube.com/watch?v=YP_P6bYvEjE
  • 31. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulses  Action potential  If the action potential (nerve impulse) starts, it is propagated over the entire axon  Impulses travel faster when fibers have a myelin sheath  http://www.youtube.com/watch?v=R0TdXkxBOkE
  • 32. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulses Figure 7.9c–d
  • 33. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulses  Repolarization  Potassium ions rush out of the neuron after sodium ions rush in, which repolarizes the membrane  The sodium-potassium pump, using ATP, restores the original configuration
  • 34. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulses Figure 7.9e–f
  • 35. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Transmission of a Signal at Synapses  Impulses are able to cross the synapse to another nerve  Neurotransmitter is released from a nerve’s axon terminal  The dendrite of the next neuron has receptors that are stimulated by the neurotransmitter  An action potential is started in the dendrite
  • 36. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Transmission of a Signal at Synapses Figure 7.10, step 1 Axon terminal Vesicles Synaptic cleft Action potential arrives Synapse Axon of transmitting neuron Receiving neuron
  • 37. Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Transmission of a Signal at Synapses Figure 7.10, step 6 Neurotrans- mitter is re- leased into synaptic cleft Neurotrans- mitter binds to receptor on receiving neuron’s membrane Vesicle fuses with plasma membrane Synaptic cleft Neurotransmitter molecules Ion channels Receiving neuron Transmitting neuron Receptor Neurotransmitter Na+ Na+ Neurotransmitter broken down and released Ion channel opens Ion channel closes