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NEURALGIA
ARATHY R NATH
NEHRU COLLEGE
NEURALGIA
NEURALGIA
 Occurs as a complication of shingles and may be anywhere
on the body.
Shingles is a viral infection characterized by a painful rash
and blisters.
Neuralgia can occur wherever the outbreak of shingles was.
The pain can be mild or severe and persistent or
intermittent.
last for months or years.
 In some cases, the pain may occur before the rash.
It will always occur along the path of a nerve, so it’s usually
isolated to one side of the body.
Postherpetic neuralgia
Trigeminal neuralgia
It is associated with pain from the trigeminal nerve,
which travels from the brain and branches to
different parts of the face.
The pain can be caused by a blood vessel pressing
down on the nerve where it meets with the
brainstem.
It can also be caused by multiple sclerosis, injury to
the nerve, or other causes.
Trigeminal neuralgia causes severe, recurrent pain
in the face, usually on one side.
 It’s most common in people who are older than 50
years.
Glossopharyngeal neuralgia
Pain from the glossopharyngeal nerve, which
is in the throat, is not very common.
This type of neuralgia produces pain in the
neck and throat.
NEURALGIA
Infection
An infection can affect your nerves.
 For example, the cause of postherpetic neuralgia
is shingles, an infection caused by the chickenpox virus.
The likelihood of having this infection increases with age.
An infection in a specific part of the body may also affect a
nearby nerve.
 For example, if you have an infection in a tooth, it may
affect the nerve and cause pain.
Multiple sclerosis
 Multiple sclerosis (MS) is a disease caused by the
deterioration of myelin, the covering of nerves. Trigeminal
neuralgia may occur in someone with MS.
Pressure on nerves
Pressure or compression of nerves may cause neuralgia.
The pressure may come from a: bone, ligament , blood
vessel , tumor
The pressure of a swollen blood vessel is a common cause
of trigeminal neuralgia.
Diabetes
 Many people with diabetes have problems with
their nerves, including neuralgia.
 The excess glucose in the bloodstream may
damage nerves.
 This damage is most common in the hands, arms,
feet, and legs.
Less common causes
If the cause of neuralgia isn’t infection, MS, diabetes, or
pressure on the nerves, it may be from one of many less-
common factors.
These include: chronic kidney disease ,medications
prescribed for cancer,fluoroquinolone antibiotics, used to
treat some infections , trauma, such as from surgery
,chemical irritation
TRIGEMINAL NEURALGIA
NEURALGIA
NEURALGIA
Trigeminal neuralgia is sudden, severe facial pain.
It's often described as a sharp shooting pain or like having
an electric shock in the jaw, teeth or gums.
It usually occurs in short, unpredictable attacks that can last
from a few seconds to about two minutes.
The attacks stop as suddenly as they start.
In most cases trigeminal neuralgia affects part or all of one
side of the face, with the pain usually felt in the lower part
of the face.
Very occasionally it can affect both sides of the face,
although not usually at the same time.
 People with the condition may experience attacks of pain
regularly for days, weeks or months at a time.
 In severe cases attacks may occur hundreds of times a day.
It's possible for the pain to improve or even disappear
altogether for several months or years at a time (remission),
although these periods tend to get shorter with time.
Some people may then go on to develop a more continuous
aching, throbbing and burning sensation, sometimes
accompanied by the sharp attacks.
Living with trigeminal neuralgia can be very difficult.
It can have a significant impact on a person's quality of life,
resulting in problems such as weight loss, isolation
and depression
NEURALGIA
NEURALGIA
NEURALGIA
NEURALGIA
NEURALGIA
NEURALGIA
MANAGEMENT
1) Pharmacological
2) Surgical
3) others
Pharmacological
• 1ST line : Carbamazepine 100,200mg
• 2nd line : phenytoin 100 mg
Baclofen 5 – 80 mg/day
Lamotrigine 25mg/day
• 3rd line : Clonazepam 4 – 8mg
valproic acid 250 – 500mg
oxacarbazepine 1200mg/day
SURGICAL
Glycerol rhizolysis
Baloon microcompression
Microvasculature decompression (MVD)
Peripheral neurectomy
Linear accelerator radiosurgery
Cryotherapy
Stereiolactic radiosurgery (SRS)
Radiofrequency gangliolysis
NEURALGIA
NEURALGIA
BRACHIAL NEURALGIA
(Shoulder to elbow )
They may follow injury , operation, inoculation or fever.
Recovery – low
symptoms: : shoulder,arm , forearm , or hand.
Causes :-
1) neck – viloent exercise, tumors,degeneration.
2) Arm- due to infections , injury
3) forearm - fractures
4) shoulder – due to arrthritis, frozen shoulder
 Symptoms :
- tightness,shifteenss of shoulder,arm,forearm
- difficulty in stretching, lifting the arm.
- altered sensation / numbness.
TREATMENT
1) Tricyclic antidepressants – nortriptylline
2) Amitriptyline (75 – 150mg) & desipramine
3)Carbamazepine (600mg/dl)
4) Gabapentin (300mg TID)
5) phenytoin & sodium valproate
6) Topical agents - lidocaine
THANK YOU

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NEURALGIA

  • 4.  Occurs as a complication of shingles and may be anywhere on the body. Shingles is a viral infection characterized by a painful rash and blisters. Neuralgia can occur wherever the outbreak of shingles was. The pain can be mild or severe and persistent or intermittent. last for months or years.  In some cases, the pain may occur before the rash. It will always occur along the path of a nerve, so it’s usually isolated to one side of the body. Postherpetic neuralgia
  • 5. Trigeminal neuralgia It is associated with pain from the trigeminal nerve, which travels from the brain and branches to different parts of the face. The pain can be caused by a blood vessel pressing down on the nerve where it meets with the brainstem. It can also be caused by multiple sclerosis, injury to the nerve, or other causes. Trigeminal neuralgia causes severe, recurrent pain in the face, usually on one side.  It’s most common in people who are older than 50 years.
  • 6. Glossopharyngeal neuralgia Pain from the glossopharyngeal nerve, which is in the throat, is not very common. This type of neuralgia produces pain in the neck and throat.
  • 8. Infection An infection can affect your nerves.  For example, the cause of postherpetic neuralgia is shingles, an infection caused by the chickenpox virus. The likelihood of having this infection increases with age. An infection in a specific part of the body may also affect a nearby nerve.  For example, if you have an infection in a tooth, it may affect the nerve and cause pain. Multiple sclerosis  Multiple sclerosis (MS) is a disease caused by the deterioration of myelin, the covering of nerves. Trigeminal neuralgia may occur in someone with MS.
  • 9. Pressure on nerves Pressure or compression of nerves may cause neuralgia. The pressure may come from a: bone, ligament , blood vessel , tumor The pressure of a swollen blood vessel is a common cause of trigeminal neuralgia. Diabetes  Many people with diabetes have problems with their nerves, including neuralgia.  The excess glucose in the bloodstream may damage nerves.  This damage is most common in the hands, arms, feet, and legs.
  • 10. Less common causes If the cause of neuralgia isn’t infection, MS, diabetes, or pressure on the nerves, it may be from one of many less- common factors. These include: chronic kidney disease ,medications prescribed for cancer,fluoroquinolone antibiotics, used to treat some infections , trauma, such as from surgery ,chemical irritation
  • 14. Trigeminal neuralgia is sudden, severe facial pain. It's often described as a sharp shooting pain or like having an electric shock in the jaw, teeth or gums. It usually occurs in short, unpredictable attacks that can last from a few seconds to about two minutes. The attacks stop as suddenly as they start. In most cases trigeminal neuralgia affects part or all of one side of the face, with the pain usually felt in the lower part of the face. Very occasionally it can affect both sides of the face, although not usually at the same time.  People with the condition may experience attacks of pain regularly for days, weeks or months at a time.  In severe cases attacks may occur hundreds of times a day.
  • 15. It's possible for the pain to improve or even disappear altogether for several months or years at a time (remission), although these periods tend to get shorter with time. Some people may then go on to develop a more continuous aching, throbbing and burning sensation, sometimes accompanied by the sharp attacks. Living with trigeminal neuralgia can be very difficult. It can have a significant impact on a person's quality of life, resulting in problems such as weight loss, isolation and depression
  • 22. MANAGEMENT 1) Pharmacological 2) Surgical 3) others Pharmacological • 1ST line : Carbamazepine 100,200mg • 2nd line : phenytoin 100 mg Baclofen 5 – 80 mg/day Lamotrigine 25mg/day • 3rd line : Clonazepam 4 – 8mg valproic acid 250 – 500mg oxacarbazepine 1200mg/day
  • 23. SURGICAL Glycerol rhizolysis Baloon microcompression Microvasculature decompression (MVD) Peripheral neurectomy Linear accelerator radiosurgery Cryotherapy Stereiolactic radiosurgery (SRS) Radiofrequency gangliolysis
  • 26. BRACHIAL NEURALGIA (Shoulder to elbow ) They may follow injury , operation, inoculation or fever. Recovery – low symptoms: : shoulder,arm , forearm , or hand. Causes :- 1) neck – viloent exercise, tumors,degeneration. 2) Arm- due to infections , injury 3) forearm - fractures 4) shoulder – due to arrthritis, frozen shoulder  Symptoms : - tightness,shifteenss of shoulder,arm,forearm - difficulty in stretching, lifting the arm. - altered sensation / numbness.
  • 27. TREATMENT 1) Tricyclic antidepressants – nortriptylline 2) Amitriptyline (75 – 150mg) & desipramine 3)Carbamazepine (600mg/dl) 4) Gabapentin (300mg TID) 5) phenytoin & sodium valproate 6) Topical agents - lidocaine