This document discusses open science business models and licensing. It begins with a word of caution about openness and business realities. It then covers open source licensing models including copyleft licenses. Open science principles are discussed along with licensing models for scientific outputs such as copyright, patents, and data. The document also discusses the growth of Creative Commons licensing and open access developments and business models. It analyzes licensing approaches for patents, databases, and open data, concluding with a discussion of open science research projects and the semantic web.