The document details the apostle Paul's ministry in Athens and Ephesus, highlighting his encounters with the idolatrous beliefs and philosophical schools of the time, particularly the Epicureans and Stoics. It outlines Paul's declaration of the one true God and the call for repentance, showcasing the varied responses to his message. The latter part emphasizes the significance of the church in Ephesus, the role of Apollos, and the transformative impact of Paul's teachings and miracles in that city.