This document discusses the practices and challenges of applying mesoscale meteorological data to air quality analyses. It provides an overview of common air quality models and their meteorological data requirements. While mesoscale data is widely used, there are challenges to address differences in perspectives between meteorology and air quality modeling, issues of model compatibility and data availability, and validating data quality for typical air quality applications. Overall, mesoscale data plays an important role in air quality modeling, though continued development is needed to better meet the needs of the air quality modeling community.