This document discusses using Python and Django for game server development. It describes using Python with Socket and Epoll for real-time features like player locations and chat. It then discusses using Django and REST APIs with polling for other functions. It provides examples of Puzzle & Dragon's game flow and API endpoints. It also notes some challenges like database access times, latency, and application server performance that can be addressed through techniques like reducing server-side computation, modifying designs, database sharding, caching, using NoSQL, and queues.