The document discusses how internal combustion engine (ICE) vehicles can help meet CO2 emissions reduction targets by 2050. It notes that global energy demand is expected to double by 2050 even as emissions must be cut 50%. ICE vehicle efficiency can be significantly improved through existing and emerging drivetrain technologies, and conventional and advanced biofuels will make a growing contribution to decarbonizing ICE fuels. A diverse mix of fuel and drivetrain types, more efficient lubricants, and interventions to reduce demand will all be needed for the transport sector to help achieve emissions targets.