This report reviews the most significant publications from the Scientific Research Group in Egypt for 2019, focusing on various machine learning and optimization techniques applied to plant disease diagnosis, satellite telemetry anomaly detection, drug toxicity prediction, and agricultural crop identification. Key highlights include a convolutional neural network model optimized through particle swarm optimization, an extreme learning machine for detecting anomalies in telemetry data, and innovative models for predicting the toxicity of biotransformed drugs. The results demonstrate competitive performance across several applications, indicating the potential for advancing research and practical applications in these domains.