Twilio provides APIs that allow developers to build voice and text messaging applications. The APIs allow developers to make and receive phone calls, send and receive text messages, buy phone numbers, record messages, and more. Developers can use the APIs by creating a Twilio account, buying a phone number, writing code to integrate with their number, and hosting the application on their own server. Twilio also offers pre-built applications called Twimlets that can be used without hosting code.