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- 1. Breast Cancinoma Clinical feactures and its Staging ~Rahul.B
- 2. It is a most common presentation and the most common site is upper outer quadrant DISCRETE LUMP
- 3. • Nipple retraction • Nipple discharge NIPPLES
- 4. • Ulceration • Peau de orange • satellite nodule • Dimpling /tethering SKIN CHANGES
- 5. It is the sign of locally advanced diseases due to the obstruction of cutaneous lymphatic drainage by infiltration of subdermal lymphatics or axilary lymph nodes PEAU D ORANGE
- 6. Cancer en cuirasse It is due to the extensive tumour infiltration of the skin of the breast ,chest , upper limb and abdomen
- 7. Any symptoms due to distant metastasis bony pain, cough, breathlessness, haemop-tysis, headache, visual disturbances, neurological deficit, epileptic fits, abdominal distension, jaundice, anorexia, weakness, weight loss, hypercalcaemia
- 8. TNM STAGING • TX-Primary tumor cant be assessed • T0-No evidence of Primary Tumor • Tis(DCIS)-Ductal carcinoma in situ • Tis(Pagets)-PAGETS diseases of the nipple not associated with (Paget's) invasive carcinoma and/or carcinoma in situ (DIS) in the underlying breast parenchyma • T1-Tumour <20 mm in greatest dimension T1mi-Tumour ≤1 mm in greatest dimension T1a-Tumour >1 mm but 55 mm in greatest dimension (round any measurement >1.0-1.9 mm to 2 mm) T1b-Tumour >5 mm but ≤10 mm in greatest dimension T1c-Tumour >10 mm but ≤20 mm in greatest dimension TUMOUR
- 9. TNM STAGING TUMOUR • T2-Tumour >20 mm but ≤50 mm in greatest dimension • T3-Tumour >50 mm in greatest dimension • T4-Tumour ofany size with direct extension to the chest wall and/or to the skin
- 10. TNM STAGING NODES • cNx-Regional lymph node cant be assessed • cN0-No regional lymph node metastasis • cN1-Metastasis to movable ipsilateral level 1 and 2 axillary lymph nodes • cN2-Metastases in ipsilateral level I, Il axillary lymph nodes that are clinically fixed or matted; or in ipsilateral internal mammary nodes in the absence of axillary lymph node metastases
- 11. TNM STAGING NODES • cN3a-Metastases in ipsilateral infraclavicular (level III axillary) lymph node(s) with or without level I, Il axillary lymph node involvement • cN3b-Metastasis in ipsilateral internal mammary lymph node(s) with level I, Il axillary lymph node metastases; • cN3c-Metastases in ipsilateral supraclavicular lymph node(s) with or without axillary or internal mammary lymph node involvement
- 12. TNM STAGING METASTASIS • M0- No clinical or radiological evidence of distant metastasis • cM1- distant metastasis by radiological and clinical means
- 13. THANK YOU