Poison, Ophelia's flowers, and Yorick's skull are symbols of death in Shakespeare's Hamlet. Poison proves the theme of death as it is used to kill many characters. Ophelia distributes flowers that symbolize themes like remembrance, deceit, and lack of faith in marriage. Yorick's skull represents the inevitability of death and reminds Hamlet of his own mortality. These symbols serve to reinforce the overarching theme of death in the play.