This document discusses various approaches and considerations for valuing technology transfer opportunities (TTOs). It begins by outlining key environment factors and valuation approaches like rules of thumb, comparables, and scientific methods. Examples of specific technologies are provided for demonstration. The challenges of long-tail distributions for valuations are discussed, emphasizing that most valuations will be wrong and money comes from outliers. Process control and negotiations are addressed. Uncertainty in assumptions is a major limitation for valuation precision.