Tomcat clustering allows multiple Tomcat application servers to work together as a single unit to provide scalability and high availability. There are two types of clustering: vertical scaling uses multiple servers on a single machine, while horizontal scaling uses independent servers across multiple machines for better performance. A typical Tomcat cluster uses a load balancer like Apache mod_jk for request distribution and a session replication method for shared state. Configuring a cluster involves setting up multiple Tomcat instances, configuring the load balancer and workers, and enabling session sharing if needed.