The EPA's refrigerant management program aims to prohibit the release of ozone-depleting substances and improve the safe handling and disposal of refrigerants. Recent changes include technician certification requirements, sales restrictions for HFC refrigerants, and modified leak repair standards, aimed at reducing greenhouse gas emissions equivalent to that of 1.5 million cars. The program emphasizes proper practices for refrigerant management, enhancing compliance, and the safe use of alternative refrigerants.