This document summarizes common anatomical variations seen in maxillary molars. The first maxillary molar typically has 3 roots but may occasionally have 4 separate roots. It can also be single-rooted in rare cases. The second maxillary molar commonly has 3 roots but may occasionally feature 2 palatal roots or fused roots. First and second maxillary molars can also be single-rooted in rare cases or have 2 roots. The third maxillary molar has the most anatomical variations and unpredictable root canal morphology, sometimes featuring 3 or 4 roots. Accessing and treating third molars can also be complicated due to their positioning and variable eruption patterns between ages 18 to 21.