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Program
1. Workshop 3: Introduction to immunoinformatics and the IMGT®
(international ImMunoGeneTics information system)
2. Workshop 4 : Knowledge of antibody sequence and structure databases
3. Workshop 5 and 6: B and T cell epitope databases
1. Workshop 7 :Allergy prediction databases
1. Workshop 8 : Databases linked to the evolution of gene molecules and
immune proteins
1. Workshop 9: Database of therapeutic monoclonal antibodies and various
related projects
Immunoinformatics
• It is a branch of immunology and bioinformatics.
• It is the intersection between immunology, biology and computer science.
Biology
Immunology
Informatic
Why studing immunoinformatic?
• It solves problems posed by immunologists.
• Provides a better platform for advancing vaccine and immunotherapeutic
•
IMGT®, the international ImMunoGeneTics
Information System®
• established in 1989 at Montpellier by the Laboratory of Molecular
Immunogenetics (LIGM) of professors MariePaule and Gérard
Lefranc (University of Montpellier 2 and CNRS).
• IMGT® specialises in the sequences, structures and genetic data of
immunoglobulins or antibodies, T receptors, major
histocompatibility complex, proteins of the IgSF and MhcSF
superfamilies, and related proteins of the immune system.
• International Reference System in Immunogenetics and
Immunoinformatics, used in Basic, medical and biotechnological
research, and in particular, in antibody engineering and
humanization
Wokshop 03 bio informatics IMGT data base
• A unique source of knowledge in immunogenetics and
immunoinformatics, at the international level.
IMGT®, the international ImMunoGeneTicsinformation system®
(http://www.imgt.org)
Wokshop 03 bio informatics IMGT data base
Wokshop 03 bio informatics IMGT data base
Wokshop 03 bio informatics IMGT data base

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Wokshop 03 bio informatics IMGT data base

  • 1. Program 1. Workshop 3: Introduction to immunoinformatics and the IMGT® (international ImMunoGeneTics information system) 2. Workshop 4 : Knowledge of antibody sequence and structure databases 3. Workshop 5 and 6: B and T cell epitope databases 1. Workshop 7 :Allergy prediction databases 1. Workshop 8 : Databases linked to the evolution of gene molecules and immune proteins 1. Workshop 9: Database of therapeutic monoclonal antibodies and various related projects
  • 2. Immunoinformatics • It is a branch of immunology and bioinformatics. • It is the intersection between immunology, biology and computer science. Biology Immunology Informatic
  • 3. Why studing immunoinformatic? • It solves problems posed by immunologists. • Provides a better platform for advancing vaccine and immunotherapeutic •
  • 4. IMGT®, the international ImMunoGeneTics Information System® • established in 1989 at Montpellier by the Laboratory of Molecular Immunogenetics (LIGM) of professors MariePaule and Gérard Lefranc (University of Montpellier 2 and CNRS). • IMGT® specialises in the sequences, structures and genetic data of immunoglobulins or antibodies, T receptors, major histocompatibility complex, proteins of the IgSF and MhcSF superfamilies, and related proteins of the immune system. • International Reference System in Immunogenetics and Immunoinformatics, used in Basic, medical and biotechnological research, and in particular, in antibody engineering and humanization
  • 6. • A unique source of knowledge in immunogenetics and immunoinformatics, at the international level. IMGT®, the international ImMunoGeneTicsinformation system® (http://www.imgt.org)

Editor's Notes

  • #3: C’est une Branche de l’immunologie et de la bioinformatique au ss. • C’est l’intersection entre l’immunologie, la biologie et l’informatique
  • #4: Elle permet de résoudre des problèmes posés par les immunologistes. • Offre une meilleure plateforme pour avancer la recherche sur le vaccin et les traitements immunothérapeutiques.
  • #6: L’IMGT® est un système d’information international pionnier dans le domaine de l’immunogénétique et de l’immunoinformatique. Il fournit à la communauté scientifique des bases de données et des outils basés sur l’IMGT-ONTOLOGY pour une exploration approfondie de la réponse immunitaire adaptative. L’IMGT® se consacre à l’avancement des connaissances scientifiques à travers ses trois principaux axes de recherche et développement. Axe I Comprendre la réponse immunitaire adaptative en déchiffrant les gènes des immunoglobulines (IG) et des récepteurs des lymphocytes T (TR) sur les loci génomiques des vertébrés à mâchoires Axe II Analyse et exploration des répertoires IG et TR exprimés à partir de comparaison avec les répertoires de référence IMGT dans des situations normales et pathologiques. Axe III Structure 2D et 3D des bases de données et des outils pour l’analyse des protéines immunitaires adaptatives et des anticorps modifiés et de la TR.
  • #7: IMGT® est spécialisé dans les séquences, structures et données génétiques des immunoglobulines (IG), des récepteurs T (TR), du complexe majeur d'histocompatibilité (MHC) des vertébrés, des protéines des superfamilles IgSF et MhcSF, et des protéines apparentées du système immunitaire.
  • #10: IMGT®, the international ImMunoGeneTics information system®. IMGT® (http://www.imgt.org) comprend des bases de données et des outils d’analyse (respectivement représentés sous forme de cylindres et de rectangles) et plus de 10 000 pages de ressources Web [1]. Les séquences et les gènes, ainsi que les structures tridimensionnelles, sont analysés et gérés selon les trois approches biologiques : génétique, génomique et structurale