Mark Kilgard's presentation at SIGGRAPH 2017 discusses OpenGL 4.6, highlighting its addition of SPIR-V support, which simplifies shader authoring. The update incorporates several extensions, improves performance, rendering quality, and resolves intellectual property issues. It also signals a transition to Vulkan by allowing offline compilation of GLSL to SPIR-V, updating associated specifications, and enhancing the OpenGL ecosystem.