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Psychopathology
O.C.D.
The specification:
• The biological approach to explaining and
treating O.C.D: genetic and neural
explanations; drug therapy.
Biological explanations: O.C.D
• You need to know the behavioural,
emotional and cognitive characteristics of
OCD.
• You need to be able to outline these
characteristics.
• You need to be able to identify them in a
description of someone’s behaviour.
O.C.D
O.C.D.
O.C.D.
Biological explanations: O.C.D
• The basic assumptions of the biological
approach are:
• Genes.
• Neural structures.
• Neurochemistry.
Biological explanations: O.C.D
• The application of the biological approach to
mental disorders is known as the medical
model.
• Mental disorders are just like physical illnesses.
• Abnormal biological processes cause abnormal
psychological processes.
Biological treatments: O.C.D
• A physical illness requires a physical
treatment.
• Drugs.
Biological explanations: Genes
• O.C.D is caused by:
• Genes
• Some people inherit genes that make
them vulnerable to the development of
O.C.D.
Biological explanations: Genes
• Twin studies.
• Twin studies have found:
• O.C.D. has a genetic basis.
Biological explanation: genes
Biological explanation: genes
Biological explanations: Genes
• Twin studies use a statistical technique to
calculate a concordance rate.
• One identical twin has O.C.D. the other
identical twin has O.C.D.
• The concordance rate from twin study research
varies significantly but suggests that inherited
genes are a significant cause of O.C.D.
Biological explanations: Genes
• This research has attempted to identify the
specific genes that cause O.C.D.
• This research has been inconclusive.
• O.C.D has a ‘polygenic’ basis.
Genes: evaluation
• No twin study has found a 100%
concordance rate.
• Genes can’t be the only cause of O.C.D.
Genes: evaluation
• The diathesis-stress model.
• Some people inherit genes that make
them vulnerable to developing O.C.D.
Mod 4 ocd
Genes: evaluation
Genes: evaluation
• This genetic vulnerability interacts with that
person’s environment.
• Physical environment.
• Social environment.
• Trauma.
Genes: evaluation
• The environment can activate or trigger
inherited genes.
• The vulnerable person develops O.C.D.
• Genome = genes inherited.
• Phenotype = the environment.
Biological explanations: Genes
Read p.37 - 38 of the psychopathology
booklet: Genetic Explanations and complete
the genetic explanation table.
Key words
• Serotonin: neurotransmitter that regulates mood.
May cause some of the symptoms of O.C.D.
• Dopamine: neurotransmitter that plays an important
role in regulating motivation and reward. May cause
some of the symptoms of O.C.D.
• Polygenic: more than one gene.
• Concordance rate: the match expressed in % that one
twin diagnosed with O.C.D. is diagnosed with O.C.D.
Neural explanations
• Abnormal brain structures.
• Abnormal brain function.
• Abnormal brain structures cause abnormal
brain function.
Mod 4 ocd
Mod 4 ocd
Mod 4 ocd
Neural explanations: abnormal brain
function
• Serotonin is a neurotransmitter.
• It regulates mood.
• When levels are normal you feel:
• Happier
• Calmer
• More focussed
• Less anxious
Neural explanations: abnormal brain
function
• When levels of serotonin are abnormal
you feel:
• Anxious
• Unfocussed
• Can’t concentrate
• Not in control of your thoughts
Neural explanations: abnormal brain
function
• Abnormally low levels of serotonin are
linked to the symptoms of O.C.D.
• One cause of O.C.D. may be the abnormal
production and processing of serotonin.
Neural explanations: abnormal brain
structures
Mod 4 ocd
Parahippocampul gyrus
Abnormal brain function: evaluation
• Research has identified two abnormalities in the
human serotonin transporter gene in DNA
samples of people with O.C.D.
• These abnormal genes cause low levels of
serotonin in the brain.
Abnormal brain function: evaluation
• Drugs that raise levels of serotonin in
the brain reduce the symptoms of O.C.D.
• Anti-depressants.
• SSRI’s
• Selective serotonin reuptake inhibitors.
Abnormal brain structures: evaluation
• Research has not identified specific brain
structures or specific brain systems that are
responsible for O.C.D.
• Brain abnormalities may be caused by
O.C.D.
• The brain abnormality may not cause
O.C.D.
Biological treatment: drugs
• The main biological treatment for O.C.D. is drug
therapy.
• Drugs that raise levels of serotonin in the brain
are prescribed.
• Anti-depressants are prescribed.
SSRI’s
Biological treatment: drugs
• SSRI’s.
• Selective Serotonin Reuptake Inhibitors.
• SSRi’s block the reabsorption of serotonin back
into the brain cell that has released it.
• Over time levels of serotonin rise in the brain.
Mod 4 ocd
Biological treatment: drugs
• Other types of anti-depressants may be
prescribed:
• SNRI’s
• Tricyclic’s
Mod 4 ocd
Mod 4 ocd
Biological treatment: drugs
• Other types of drugs may be prescribed:
• Anti-anxiety drugs.
• Benzodiazapines.
Mod 4 ocd
Drugs: evaluation
• Drugs work.
• They reduce the symptoms of
O.C.D.
• A meta-analysis (2009) found
that SSRI’s were effective in
reducing the symptoms of
O.C.D.
Drugs: evalaution
Drugs are cheap.
Biological treatment: drugs
Drugs have side
effects.
Biological treatment: drugs
• Negative results are
not published.
• Researchers only
send reports of
research that find
positive results to
academic journals.

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Mod 4 ocd

  • 2. O.C.D. The specification: • The biological approach to explaining and treating O.C.D: genetic and neural explanations; drug therapy.
  • 3. Biological explanations: O.C.D • You need to know the behavioural, emotional and cognitive characteristics of OCD. • You need to be able to outline these characteristics. • You need to be able to identify them in a description of someone’s behaviour.
  • 7. Biological explanations: O.C.D • The basic assumptions of the biological approach are: • Genes. • Neural structures. • Neurochemistry.
  • 8. Biological explanations: O.C.D • The application of the biological approach to mental disorders is known as the medical model. • Mental disorders are just like physical illnesses. • Abnormal biological processes cause abnormal psychological processes.
  • 9. Biological treatments: O.C.D • A physical illness requires a physical treatment. • Drugs.
  • 10. Biological explanations: Genes • O.C.D is caused by: • Genes • Some people inherit genes that make them vulnerable to the development of O.C.D.
  • 11. Biological explanations: Genes • Twin studies. • Twin studies have found: • O.C.D. has a genetic basis.
  • 14. Biological explanations: Genes • Twin studies use a statistical technique to calculate a concordance rate. • One identical twin has O.C.D. the other identical twin has O.C.D. • The concordance rate from twin study research varies significantly but suggests that inherited genes are a significant cause of O.C.D.
  • 15. Biological explanations: Genes • This research has attempted to identify the specific genes that cause O.C.D. • This research has been inconclusive. • O.C.D has a ‘polygenic’ basis.
  • 16. Genes: evaluation • No twin study has found a 100% concordance rate. • Genes can’t be the only cause of O.C.D.
  • 17. Genes: evaluation • The diathesis-stress model. • Some people inherit genes that make them vulnerable to developing O.C.D.
  • 20. Genes: evaluation • This genetic vulnerability interacts with that person’s environment. • Physical environment. • Social environment. • Trauma.
  • 21. Genes: evaluation • The environment can activate or trigger inherited genes. • The vulnerable person develops O.C.D. • Genome = genes inherited. • Phenotype = the environment.
  • 22. Biological explanations: Genes Read p.37 - 38 of the psychopathology booklet: Genetic Explanations and complete the genetic explanation table.
  • 23. Key words • Serotonin: neurotransmitter that regulates mood. May cause some of the symptoms of O.C.D. • Dopamine: neurotransmitter that plays an important role in regulating motivation and reward. May cause some of the symptoms of O.C.D. • Polygenic: more than one gene. • Concordance rate: the match expressed in % that one twin diagnosed with O.C.D. is diagnosed with O.C.D.
  • 24. Neural explanations • Abnormal brain structures. • Abnormal brain function. • Abnormal brain structures cause abnormal brain function.
  • 28. Neural explanations: abnormal brain function • Serotonin is a neurotransmitter. • It regulates mood. • When levels are normal you feel: • Happier • Calmer • More focussed • Less anxious
  • 29. Neural explanations: abnormal brain function • When levels of serotonin are abnormal you feel: • Anxious • Unfocussed • Can’t concentrate • Not in control of your thoughts
  • 30. Neural explanations: abnormal brain function • Abnormally low levels of serotonin are linked to the symptoms of O.C.D. • One cause of O.C.D. may be the abnormal production and processing of serotonin.
  • 31. Neural explanations: abnormal brain structures
  • 34. Abnormal brain function: evaluation • Research has identified two abnormalities in the human serotonin transporter gene in DNA samples of people with O.C.D. • These abnormal genes cause low levels of serotonin in the brain.
  • 35. Abnormal brain function: evaluation • Drugs that raise levels of serotonin in the brain reduce the symptoms of O.C.D. • Anti-depressants. • SSRI’s • Selective serotonin reuptake inhibitors.
  • 36. Abnormal brain structures: evaluation • Research has not identified specific brain structures or specific brain systems that are responsible for O.C.D. • Brain abnormalities may be caused by O.C.D. • The brain abnormality may not cause O.C.D.
  • 37. Biological treatment: drugs • The main biological treatment for O.C.D. is drug therapy. • Drugs that raise levels of serotonin in the brain are prescribed. • Anti-depressants are prescribed.
  • 39. Biological treatment: drugs • SSRI’s. • Selective Serotonin Reuptake Inhibitors. • SSRi’s block the reabsorption of serotonin back into the brain cell that has released it. • Over time levels of serotonin rise in the brain.
  • 41. Biological treatment: drugs • Other types of anti-depressants may be prescribed: • SNRI’s • Tricyclic’s
  • 44. Biological treatment: drugs • Other types of drugs may be prescribed: • Anti-anxiety drugs. • Benzodiazapines.
  • 46. Drugs: evaluation • Drugs work. • They reduce the symptoms of O.C.D. • A meta-analysis (2009) found that SSRI’s were effective in reducing the symptoms of O.C.D.
  • 48. Biological treatment: drugs Drugs have side effects.
  • 49. Biological treatment: drugs • Negative results are not published. • Researchers only send reports of research that find positive results to academic journals.