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Sample Text, Table
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US Industry Study with Forecasts to 2010 & 2015
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Biocompatible Materials
Study #2111
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Table of Contents
Introduction
Executive Summary
Market EnvironmenT
General....................................................4
Economic Factors.......................................5
Demographic Patterns.................................8
Health Care Trends................................... 10
	 Medical Conditions................................ 11
		 Chronic Conditions............................. 12
		 Acute Conditions............................... 14
	 Health Insurance  Reimbursement......... 15
	 National Health Expenditures.................. 18
	 Medical Providers.................................. 21
		 Hospitals.......................................... 24
		 Physicians........................................ 24
		 Dentists........................................... 25
		 Outpatient Facilities.......................... 26
		 Skilled Nursing Homes........................ 27
	 Patient Activity.................................... 27
		 Surgical Procedures............................ 29
		 Outpatient Episodes........................... 29
	 Medical Product Shipments..................... 31
		 Pharmaceuticals  Biologicals............. 32
		 Surgical  Medical Instruments............ 33
		 Surgical Appliances  Supplies............ 34
		 Electromedical Equipment................... 34
		 In Vitro Diagnostic Products................ 35
		 Dental Products................................. 35
		 Ophthalmic Goods.............................. 36
		 Other Medical Products....................... 36
Regulatory Considerations......................... 37
	 Medical Devices.................................... 37
	 Drug Delivery Systems........................... 39
Historical Demand Patterns........................ 40
Pricing Trends......................................... 42
US Trade................................................. 42
International Markets............................... 44
BIOCOMPATIBLE MATERIALS
General.................................................. 46
Synthetic Polymers................................... 48
	 Thermoplastic Elastomers....................... 51
		 Silicone Elastomers............................ 53
		 Styrene Block Copolymers................... 54
		 Thermoplastic Copolyesters................. 55
		 Thermoplastic Polyamides................... 55
		 Thermoplastic Polyolefins.................... 56
		 Thermoplastic Polyurethanes............... 56
		 Thermoplastic Vulcanizates................. 56
	 Polyvinyl Chloride................................. 57
		 Environmental  Safety Concerns......... 58
		 Production........................................ 60
		 Resin Properties................................ 60
		 Producers  Compounds...................... 61
	 Fluoropolymers..................................... 63
		 PTFE................................................ 64
		 Modified PTFE................................... 65
		 FEP................................................. 66
		 ETFE................................................ 67
		 PFA................................................. 67
		 MFA................................................. 67
	 Polyurethane........................................ 68
		 Production  Properties...................... 69
		 Applications..................................... 69
		 Producers  Compounds...................... 70
	 Polycarbonate...................................... 71
		 Production........................................ 72
		 Applications..................................... 73
		 Producers  Compounds...................... 73
	 Silicone............................................... 74
		 Production........................................ 75
		 Applications..................................... 76
		 Producers  Compounds...................... 79
	 Acrylic Compounds................................ 79
		 Applications..................................... 81
		 Producers  Compounds...................... 83
	 Thermoplastic Polyesters........................ 84
		 Types of Compounds........................... 85
		 Properties........................................ 86
		 Applications..................................... 87
		 Producers  Compounds...................... 88
	 Polypropylene...................................... 89
		 Production  Types............................ 90
		 Applications..................................... 91
		 Producers  Compounds...................... 91
	 Low Density Polyethylenes..................... 92
		 Production  Types............................ 93
		 Properties........................................ 95
		 Applications..................................... 96
		 Producers  Compounds...................... 96
	 Nylon.................................................. 97
		 Production  Types............................ 97
		 Applications..................................... 98
		 Producers  Compounds...................... 99
	 Sulfone Resins...................................... 99
	 High Density Polyethylenes.................. 101
	 Other Synthetic Biocompatible Polymers	103
Natural Polymers.................................... 111
	 Cellulose Polymers.............................. 113
		 Drug Delivery.................................. 114
		 Surgical Appliances  Supplies.......... 116
	 Collagen............................................ 117
		 Surgical Appliances  Supplies.......... 118
		 Dental Products............................... 119
		 Producers....................................... 119
	 Starch Blends..................................... 121
		 Other Natural Polymers..................... 123
			 Hyaluronic Acid............................ 124
			 Alginates.................................... 126
			 Carrageenan................................ 127
			 Other Natural Polymers.................. 128
Biocompatible Metals............................. 130
	 Precious Metals.................................. 132
		 Gold.............................................. 133
		 Silver............................................. 133
		 Other Precious Metals....................... 135
	 Stainless Steel................................... 136
	 Titanium........................................... 139
	 Other Biocompatible Metals.................. 143
Biocompatible Ceramics.......................... 144
	 Porcelain........................................... 146
	 Alumina............................................ 146
	 Hydroxyapatite................................... 147
	 Zirconia............................................. 147
	 Other Ceramics  Related Materials........ 147
	 Surgical Appliances  Supplies.............. 148
	 Dental Products.................................. 150
	 Electromedical Equipment.................... 152
APPLICATIONS
General................................................ 153
Surgical Appliances  Supplies................. 155
Surgical  Medical Instruments................ 162
Dental Products..................................... 164
Drug Delivery........................................ 167
Electromedical Equipment....................... 172
In Vitro Diagnostic Products.................... 174
Ophthalmic Goods.................................. 176
INDUSTRY STRUCTURE
General................................................ 178
Market Share......................................... 180
Competitive Strategies............................ 181
Mergers  Acquisitions............................ 186
Licensing  Related Agreements............... 189
Research  Development......................... 193
Channels of Distribution.......................... 194
Marketing............................................. 196
Manufacturing....................................... 197
Company Profiles
			 (listed on next page)
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List of Tables/Charts
Company Profiles
Allegheny Technologies .......................... 200
Angiotech Pharmaceuticals...................... 205
Arkema SA............................................ 207
Artimplant AB....................................... 209
BASF AG............................................... 211
Bayer AG.............................................. 213
BioSyntech Incorporated......................... 215
Celanese Corporation.............................. 216
Chevron Phillips Chemical........................ 218
Dow Chemical........................................ 219
Dow Corning......................................... 221
DuPont (EI) de Nemours.......................... 223
Eastman Chemical ................................. 225
Exxon Mobil.......................................... 227
FMC Corporation.................................... 228
General Electric..................................... 230
Genzyme Corporation.............................. 232
Georgia Gulf.......................................... 233
Gore (WL)  Associates........................... 234
Imperial Chemical Industries.................... 237
Ineos Group.......................................... 239
Integra LifeSciences .............................. 240
International Specialty Products............... 242
Johnson  Johnson................................ 243
Johnson Matthey plc.............................. 244
Lyondell Chemical ................................. 245
Memry Corporation................................. 246
Morgan Crucible..................................... 249
Orthovita Incorporated........................... 251
OxyVinyls LP......................................... 253
PolyOne Corporation............................... 254
Saint-Gobain......................................... 255
Solvay SA............................................. 257
Total SA............................................... 260
Westlake Plastics .................................. 261
Additional Companies............................. 262
Executive Summary
	 1	 Summary Table....................................3
Market EnvironmenT
	 1	 Macroeconomic Indicators.....................7
	 2	 Resident Population by Age Group..........9
	 3	 Medical Conditions
			 by Duration  Type......................... 12
	 4	 Health Insurance Coverage.................. 18
	 5	 National Health Expenditures.............. 21
	 6	 Selected Medical Providers by Type....... 23
	 7	 Selected Patient Activity by Type......... 28
	 8	 Medical Product Shipments by Type...... 32
	 9	 Biocompatible Material Demand,
			 1995-2005 .................................. 41
	10	 US Trade in Biocompatible Materials..... 43
	11	 World Biocompatible Material
			 Demand by Region.......................... 45
MATERIALS
	 1	 Biocompatible Material
			 Demand by Type............................. 47
	Cht	 Biocompatible Material
			 Demand by Type, 2005.................... 47
	 2	 Synthetic Biocompatible
			 Polymer Demand by Type................. 50
	Cht	 Synthetic Biocompatible Polymer
			 Demand by Type, 2005.................... 51
	 3	 Biocompatible Thermoplastic
			 Elastomer Demand by Application..... 53
	 4	 Biocompatible Polyvinyl
			 Chloride Demand by Application....... 58
	 5	 Biocompatible Fluoropolymer
			 Demand by Application................... 64
	 6	 Biocompatible Polyurethane
			 Demand by Application................... 68
	 7	 Biocompatible Polycarbonate
			 Demand by Application................... 72
	 8	 Biocompatible Silicone
			 Demand by Application................... 75
	 9	 Biocompatible Acrylic
			 Demand by Application................... 81
	10	 Biocompatible Thermoplastic
			 Polyester Demand by Application...... 85
	11	 Biocompatible Polypropylene
			 Demand by Application................... 89
	12	 Biocompatible Low Density
			 Polyethylenes Demand
			 by Application............................... 93
	13	 Biocompatible Nylon
			 Demand by Application................... 97
	14	 Biocompatible Sulfone
			 Resin Demand by Application......... 101
	15	 Biocompatible High Density
			 Polyethylenes Demand
			 by Application............................. 103
	16	 Other Synthetic Biocompatible
			 Polymer Demand by Application...... 105
	17	 Natural Biocompatible Polymer
			 Demand by Type........................... 112
	Cht	 Natural Biocompatible Polymer
			 Demand by Type, 2005.................. 112
	18	 Biocompatible Cellulose Polymer
			 Demand by Application................. 113
	19	 Biocompatible Collagen
			 Demand by Application................. 118
	20	 Biocompatible Starch Blend
			 Demand by Application................. 123
	21	 Other Natural Biocompatible
			 Polymer Demand
			 by Type  Application................... 124
	22	 Biocompatible Metal
			 Demand by Type........................... 131
	Cht	 Biocompatible Metal Demand
			 by Type, 2005.............................. 131
	23	 Biocompatible Precious
			 Metal Demand by Application......... 132
	24	 Biocompatible Stainless
			 Steel Demand by Application.......... 139
	25	 Biocompatible Titanium
			 Demand by Application................. 143
	26	 Other Biocompatible Metal
			 Demand by Application................. 144
	27	 Biocompatible Ceramic Demand
			 by Type  Application................... 145
APPLICATIONS
	 1	 Biocompatible Material
			 Demand by Application................. 154
	Cht	 Biocompatible Material
			 Demand by Application, 2005......... 154
	 2	 Biocompatible Material Demand in
			 Surgical Appliances  Supplies....... 156
	 3	 Biocompatible Material Demand in
			 Surgical  Medical Instruments....... 164
	 4	 Biocompatible Material
			 Demand in Dental Products ........... 165
	 5	 Biocompatible Material
			 Demand in Drug Delivery............... 168
	 6	 Biocompatible Material Demand
			 in Electromedical Equipment.......... 173
	 7	 Biocompatible Material Demand in
			 In Vitro Diagnostic Products........... 175
	 8	 Biocompatible Material Demand
			 in Ophthalmic Goods..................... 177
INDUSTRY STRUCTURE
	 1	 US Biocompatible Material
			 Sales by Company, 2005................ 179
	Cht	 Biocompatible Material
			 Market Share, 2005....................... 181
	 2	 Selected Acquisitions 
			 Divestitures................................. 188
	 3	 Selected Cooperative Agreements....... 190
Study #2111
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US demand to grow 6.6%
per year through 2010
Demand for biocompatible materials in
the US will increase 6.6 percent annu-
ally to $3.7 billion in 2010. Synthetic
polymers will continue to record more
than half of revenues and post slightly
better than average gains in demand.
Based on quality and safety advantages
in catheters, IV administration sets, IV
and blood containers, and orthopedic
implants, engineered resins -- especially
polycarbonate, thermoplastic elasto-
mers, silicone and sulfone compounds
-- will provide the best growth opportuni-
ties. By contrast, demand for polyvinyl
chloride in biocompatible products will
expand at a below average pace due to
ongoing concerns about DEHP plasti-
cizer migration.
Hyaluronic acid, collagen
to pace natural polymers
Increasing use in pharmaceutical excipi-
ents, drug delivery systems, cosmetic
implants, tissue engineering and wound
dressings will boost demand for natural
polymers. Hyaluronic acid and collagen
will post the strongest gains as new
improved bioengineered formulations
broaden applications in cosmetic and
orthopedic surgery as well as in wound
management. Based on well-established
performance results, cellulose polymers
and starch blends will continue to record
substantial gains in pharmaceutical
excipients and controlled-release drug
delivery systems.
Titanium to provide best
prospects among metals
Precious metals will sustain the largest
demand value among biocompatible
metals based on high price and wide-
spread use in dental repair and restora-
tion products. However, reflecting ad-
vantages of high strength, low modulus
and strong body fluid resistance, titanium
and titanium alloys will provide the best
growth opportunities. These metals will
extend applications in joint replacement
systems; dental implants; fusion cages;
trauma fixation devices; pacemaker
and defibrillator cases; cochlear implant
houses; stents; and mechanical heart
valves. The penetration of titanium and
titanium alloys into new and existing
uses will weaken the growth potential of
stainless steel and other biocompatible
metals, such as cobalt chromium alloys.
Ceramics to be fastest
growing biocompatibles
Ceramics will realize the strongest
growth among all biocompatible materi-
als as advances in the properties and
processing ease of these compounds
broaden their uses. New generations of
alumina-zirconia nanocomposites are
expected to see the strongest gains.
These high density structures incorpo-
rate greater resistance to cracking, an
important advantage in orthopedic im-
plants, fixation devices, and dental repair
and restoration products.
photocourtesyofUSDA
Spurred by expanding applications in cosmetic surgery and wound management, hyaluronic acid and
collagen will generate the fastest gains in US demand among biocompatible natural polymers.
US Biocompatible Materials
Demand, 2005
($2.7 billion)
Synthetic
Polymers
52%
Metals
16%
Natural
Polymers
22%
Ceramics
10%
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biocompatible materials
Synthetic Polymers
	 Synthetic polymers will remain the dominant materials employed
in biocompatible products. Total synthetic polymer demand in biocom-
patible applications is projected to increase 4.2 percent annually to 695
million pounds, valued at nearly $2 billion, in 2010. These amounts will
correspond to nearly 72 percent of the volume and almost 53 percent of
the value of biocompatible materials consumed in the US.
	 The leading position of synthetic polymers in various medical,
dental pharmaceutical segments reflects ongoing innovations and im-
provements in compounds. Technological advances have made available
resins that meet the needs of end-use products as to biocompatibility,
chemical resistance, infection resistance, clarity, sterilization compat-
ibility, processing ease, and overall quality and cost efficiency. All or
virtually all medical tubing devices, IV containers and components,
syringe cartridges, specimen tubes, and intraocular and contact lenses,
as well as a large percentage of dental materials and devices, orthopedic
implants, drug delivery systems and wound management supplies, are
composed of synthetic polymers. Further improvements and refinements
in materials will extend the range of biocompatible products adaptable to
commodity and engineered plastic resins.
	 Growth opportunities for synthetic biocompatible polymers will
extend into most classes of commodity and engineered resins. Based on
cost effectiveness and the availability of improving grades, commodity
resins, especially polyvinyl chloride, will continue to dominate low- and
medium-value applications in less invasive supplies and devices, such
as IV containers and components. Conversely, demand for products
with high biocompatibility requirements, including dental and orthope-
dic implants, and injectable drug delivery systems, will be met mostly
through engineered plastics. Thermoplastic elastomers, fluoropolymers,
thermoset polyurethanes, silicone, acrylics and thermoplastic polyesters
48						
Sample Text,
Table  Forecast
sample text
TABLE III-2
SYNTHETIC BIOCOMPATIBLE POLYMER DEMAND BY TYPE
(million dollars)
Item 						 1995	 2000	 2005	 2010	 2015
Medical Product Shipments (bil $)		 152	 245	 379	 530	 735
	 $ biocomp polymers/000$ shpts		 3.98	 3.61	 3.75	 3.72	 3.58
					
Synthetic Biocompatible Polymers		 605	 885	 1420	 1970	 2630
	 Thermoplastic Elastomers (TPEs)		 72	 109	 191	 285	 400
	 Polyvinyl Chloride (PVC)			 90	 119	 179	 223	 265
	 Fluoropolymers				 70	 103	 161	 219	 290
	 Polyurethane (PUR)			 45	 88	 149	 210	 283
	 Polycarbonate (PC)			 59	 83	 134	 205	 287
	 Silicone				 50	 72	 101	 150	 220
	 Acrylic				 52	 71	 100	 130	 166
	 Thermoplastic Polyesters (TPs)		 30	 45	 77	 106	 140
	 Polypropylene (PP)			 26	 36	 66	 92	 125
	 Low Density Polyethylene (LDPE)	 27	 34	 55	 71	 91
	 Nylon					 19	 26	 41	 52	 64
	 Sulfone Resins				 12	 18	 31	 46	 65
	 High Density Polyethylene (HDPE)	 9	 12	 21	 28	 36
	 Other					 44	 69	 114	 153	 198
					
	 $/lb						 1.69	 1.92	 2.51	 2.83	 3.09
Synthetic Biocomp Polymers (mil lbs)	 358	 460	 565	 695	 850
sample
table
“Demand for low density
polyethylenes (including
conventional low density,
linear low density, ultra low
density and metallocene
grades) in the production
of biocompatible products
is projected to increase 3.6
percent annually to 69.8
million pounds, valued at
$71 million, in 2010. Fiber
applications in bandages,
wound dressings and incon-
tinence garments will lead
gains. In other biocompat-
ible products adaptable to
LDPEs, such as ...”
--Section III, pg. 92
Copyright 2006 The Freedonia Group, Inc.
Study #2111
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Orthovita Incorporated
45 Great Valley Parkway
Malvern, PA 19355
610-640-1775
http://www.orthovita.com
Sales: $35 million (2005)
US Sales: $32 million (2005)
Employment: 140 (2005)
Key Products:synthetic, biologically active, tissue engineering products
	 Orthovita is a biomaterials firm. The Company develops, manu-
factures and commercializes synthetic, biologically active, tissue
engineering products for orthopedic and neurosurgical applications,
including bone regeneration.
	 Orthovita’s synthetic, biologically active, tissue engineering
products include VITOSS bone graft substitutes, VITOMATRIX par-
ticulate synthetic scaffold biomaterials, IMBIBE bone marrow aspirate
and delivery devices, VITAGEL composite liquid surgical hemostat,
CELLPACKER plasma collection systems, CORTOSS synthetic corti-
cal bone, ALIQUOT micro delivery systems and ENDOSKELETON
TA vertebral body replacement structural devices. VITOSS bone graft
substitute is an ultra-porous resorbable beta-tricalcium phosphate bone
void filler material adaptable to a wide range of spinal, dental and
orthopedic procedures. VITOMATRIX particulate synthetic scaffold
biomaterials, which are based on proprietary beta-tricalcium phosphate
biomaterials, are used to make VITOSS bone graft substitutes.
	 IMBIBE bone marrow aspirate and delivery devices from Ortho-
vita extract and harvest bone marrow from patients for use in bone
166						
COMPANY PROFILES
TABLE IV-6
BIOCOMPATIBLE MATERIAL DEMAND
IN ELECTROMEDICAL EQUIPMENT
(million dollars)
Item 						 1995	 2000	 2005	 2010	 2015
Electromedical Equipment Demand		 24.0	 37.0	 61.0	 87.0	 120.0
	 Synthetic Polymers:			 18.0	 27.0	 43.0	 58.0	 76.0
		 Thermoplastic Elastomers		 5.3	 9.1	 14.4	 20.3	 28.3
		 Nylon				 5.5	 7.4	 12.2	 15.7	 19.0
		 Acrylic				 0.2	 0.3	 0.5	 0.8	 1.2
		 High Density Polyethylene		 0.1	 0.2	 0.4	 0.5	 0.6
		 Other				 6.9	 10.0	 15.5	 20.7	 26.9
	 Metals:				 2.0	 3.0	 5.0	 7.0	 9.0
		 Stainless Steel				 1.2	 1.8	 2.3	 2.9	 3.6
		 Titanium				 0.2	 0.3	 1.2	 1.6	 2.2
		 Other				 0.6	 0.9	 1.5	 2.5	 3.2
	 Ceramics				 4.0	 7.0	 13.0	 22.0	 35.0
Sample Profile,
Table  Chart
sample
profile
sample
table
TABLE V-1
BIOCOMPATIBLE MATERIAL MARKET SHARE, 2005
($2.7 billion)
Market
Leaders
31.5%
Others
68.5%
Dow Chem
Georgia G
Exxon Mob
OxyVinyls
BASF
DuPont
PolyOne
Bayer
Allegheny
GE
1.7%
2.0%
2.4%
2.6%
3.0%
3.1%
3.5%
3.9%
4.1%
5.2%
sample
chart
Copyright 2006 The Freedonia Group, Inc.
The Freedonia Group, Inc. 767 Beta Drive • Cleveland, OH • 44143-2326 • USA • Web site: www.freedoniagroup.com
Tel US: 800.927.5900 or +1 440.684.9600 • Fax: +1 440.646.0484 • e-mail: info@freedoniagroup.com
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INDUSTRY MARKET RESEARCH FOR BUSINESS
LEADERS, STRATEGISTS, DECISION MAKERS
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chemicals. This study analyzes the $5.4 billion US
cosmeceutical industry for 2010 and 2015 by product
and chemical. It also evaluates company market
share and profiles leading players.
#2114....................10/2006..................... $4400
Cosmetic Surgery Products
US demand for cosmetic surgery products will grow
9.1% annually through 2010, driven by an obses-
sion with youth coupled with an aging population
and greater product availability. Nonsurgical markets
(e.g., injections, dermal resurfacing, micro-dermabra-
sion) will lead gains based on consumer preferences
for less invasive treatments. This study analyzes the
$1.6 billion US cosmetic surgery product industry to
2010 and 2015 by material, product and procedure.
It also evaluates market share and profiles major
players.
#2099....................09/2006..................... $4300
Natural Polymers	
US natural polymer demand will grow 5.9% annually
through 2010 based on increased food production
and opportunities in packaging and medical uses.
Starch and fermentation products will grow the fastest
and surpass cellulose ethers as the dominant type
by 2015. The food and beverage market will remain
dominant while medical uses will lead gains. The
study analyzes the $2.7 billion US natural polymer
industry for 2010 and 2015 by product and market. It
also details market share and profiles major players.
#2156....................01/2007..................... $4300
Implantable Medical Devices
US medical implant demand will rise 9.3% yearly
through 2011. Cardiac implants will remain the top-
selling group, led by stents and defibrillators. Bone
cement, tissue and spinal implants will pace gains in
the orthopedic segment. Other fast-growing types in-
clude neurological stimulators, cochlear devices and
gastric bands. This study analyzes the $27.9 billion
US medical implant industry, with forecasts for 2011
and 2016 by material and product. It also evaluates
market share and profiles major players.
#2255....................10/2007..................... $4500

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2111smwe

  • 1. INDUSTRY MARKET RESEARCH FOR BUSINESS LEADERS, STRATEGISTS, DECISION MAKERS 767 Beta Drive Cleveland, OH • 44143-2326 • USA Toll Free US Tel: 800.927.5900 or +1 440.684.9600 Fax: +1 440.646.0484 E-mail: info@freedoniagroup.com The Freedonia Group www.freedoniagroup.com Table of Contents 2 List of Tables & Charts 3 Study Overview 4 Sample Text, Table & Chart 5 Sample Profile, Table & Forecast 6 Order Form 7 About Freedonia, Custom Research, Related Studies, Corporate Use License 8 CLICK TO VIEW US Industry Study with Forecasts to 2010 & 2015 Study #2111 | September 2006 | $4400 | 264 pages Biocompatible Materials
  • 2. Study #2111 September 2006 $4400 264 Pages Biocompatible Materials US Industry Study with Forecasts to 2010 & 2015 Page Order now, click here! Click here to purchase online Table of Contents Introduction Executive Summary Market EnvironmenT General....................................................4 Economic Factors.......................................5 Demographic Patterns.................................8 Health Care Trends................................... 10 Medical Conditions................................ 11 Chronic Conditions............................. 12 Acute Conditions............................... 14 Health Insurance Reimbursement......... 15 National Health Expenditures.................. 18 Medical Providers.................................. 21 Hospitals.......................................... 24 Physicians........................................ 24 Dentists........................................... 25 Outpatient Facilities.......................... 26 Skilled Nursing Homes........................ 27 Patient Activity.................................... 27 Surgical Procedures............................ 29 Outpatient Episodes........................... 29 Medical Product Shipments..................... 31 Pharmaceuticals Biologicals............. 32 Surgical Medical Instruments............ 33 Surgical Appliances Supplies............ 34 Electromedical Equipment................... 34 In Vitro Diagnostic Products................ 35 Dental Products................................. 35 Ophthalmic Goods.............................. 36 Other Medical Products....................... 36 Regulatory Considerations......................... 37 Medical Devices.................................... 37 Drug Delivery Systems........................... 39 Historical Demand Patterns........................ 40 Pricing Trends......................................... 42 US Trade................................................. 42 International Markets............................... 44 BIOCOMPATIBLE MATERIALS General.................................................. 46 Synthetic Polymers................................... 48 Thermoplastic Elastomers....................... 51 Silicone Elastomers............................ 53 Styrene Block Copolymers................... 54 Thermoplastic Copolyesters................. 55 Thermoplastic Polyamides................... 55 Thermoplastic Polyolefins.................... 56 Thermoplastic Polyurethanes............... 56 Thermoplastic Vulcanizates................. 56 Polyvinyl Chloride................................. 57 Environmental Safety Concerns......... 58 Production........................................ 60 Resin Properties................................ 60 Producers Compounds...................... 61 Fluoropolymers..................................... 63 PTFE................................................ 64 Modified PTFE................................... 65 FEP................................................. 66 ETFE................................................ 67 PFA................................................. 67 MFA................................................. 67 Polyurethane........................................ 68 Production Properties...................... 69 Applications..................................... 69 Producers Compounds...................... 70 Polycarbonate...................................... 71 Production........................................ 72 Applications..................................... 73 Producers Compounds...................... 73 Silicone............................................... 74 Production........................................ 75 Applications..................................... 76 Producers Compounds...................... 79 Acrylic Compounds................................ 79 Applications..................................... 81 Producers Compounds...................... 83 Thermoplastic Polyesters........................ 84 Types of Compounds........................... 85 Properties........................................ 86 Applications..................................... 87 Producers Compounds...................... 88 Polypropylene...................................... 89 Production Types............................ 90 Applications..................................... 91 Producers Compounds...................... 91 Low Density Polyethylenes..................... 92 Production Types............................ 93 Properties........................................ 95 Applications..................................... 96 Producers Compounds...................... 96 Nylon.................................................. 97 Production Types............................ 97 Applications..................................... 98 Producers Compounds...................... 99 Sulfone Resins...................................... 99 High Density Polyethylenes.................. 101 Other Synthetic Biocompatible Polymers 103 Natural Polymers.................................... 111 Cellulose Polymers.............................. 113 Drug Delivery.................................. 114 Surgical Appliances Supplies.......... 116 Collagen............................................ 117 Surgical Appliances Supplies.......... 118 Dental Products............................... 119 Producers....................................... 119 Starch Blends..................................... 121 Other Natural Polymers..................... 123 Hyaluronic Acid............................ 124 Alginates.................................... 126 Carrageenan................................ 127 Other Natural Polymers.................. 128 Biocompatible Metals............................. 130 Precious Metals.................................. 132 Gold.............................................. 133 Silver............................................. 133 Other Precious Metals....................... 135 Stainless Steel................................... 136 Titanium........................................... 139 Other Biocompatible Metals.................. 143 Biocompatible Ceramics.......................... 144 Porcelain........................................... 146 Alumina............................................ 146 Hydroxyapatite................................... 147 Zirconia............................................. 147 Other Ceramics Related Materials........ 147 Surgical Appliances Supplies.............. 148 Dental Products.................................. 150 Electromedical Equipment.................... 152 APPLICATIONS General................................................ 153 Surgical Appliances Supplies................. 155 Surgical Medical Instruments................ 162 Dental Products..................................... 164 Drug Delivery........................................ 167 Electromedical Equipment....................... 172 In Vitro Diagnostic Products.................... 174 Ophthalmic Goods.................................. 176 INDUSTRY STRUCTURE General................................................ 178 Market Share......................................... 180 Competitive Strategies............................ 181 Mergers Acquisitions............................ 186 Licensing Related Agreements............... 189 Research Development......................... 193 Channels of Distribution.......................... 194 Marketing............................................. 196 Manufacturing....................................... 197 Company Profiles (listed on next page)
  • 3. Study #2111 September 2006 $4400 264 Pages Biocompatible Materials US Industry Study with Forecasts to 2010 2015 Page Order now, click here! Click here to purchase online List of Tables/Charts Company Profiles Allegheny Technologies .......................... 200 Angiotech Pharmaceuticals...................... 205 Arkema SA............................................ 207 Artimplant AB....................................... 209 BASF AG............................................... 211 Bayer AG.............................................. 213 BioSyntech Incorporated......................... 215 Celanese Corporation.............................. 216 Chevron Phillips Chemical........................ 218 Dow Chemical........................................ 219 Dow Corning......................................... 221 DuPont (EI) de Nemours.......................... 223 Eastman Chemical ................................. 225 Exxon Mobil.......................................... 227 FMC Corporation.................................... 228 General Electric..................................... 230 Genzyme Corporation.............................. 232 Georgia Gulf.......................................... 233 Gore (WL) Associates........................... 234 Imperial Chemical Industries.................... 237 Ineos Group.......................................... 239 Integra LifeSciences .............................. 240 International Specialty Products............... 242 Johnson Johnson................................ 243 Johnson Matthey plc.............................. 244 Lyondell Chemical ................................. 245 Memry Corporation................................. 246 Morgan Crucible..................................... 249 Orthovita Incorporated........................... 251 OxyVinyls LP......................................... 253 PolyOne Corporation............................... 254 Saint-Gobain......................................... 255 Solvay SA............................................. 257 Total SA............................................... 260 Westlake Plastics .................................. 261 Additional Companies............................. 262 Executive Summary 1 Summary Table....................................3 Market EnvironmenT 1 Macroeconomic Indicators.....................7 2 Resident Population by Age Group..........9 3 Medical Conditions by Duration Type......................... 12 4 Health Insurance Coverage.................. 18 5 National Health Expenditures.............. 21 6 Selected Medical Providers by Type....... 23 7 Selected Patient Activity by Type......... 28 8 Medical Product Shipments by Type...... 32 9 Biocompatible Material Demand, 1995-2005 .................................. 41 10 US Trade in Biocompatible Materials..... 43 11 World Biocompatible Material Demand by Region.......................... 45 MATERIALS 1 Biocompatible Material Demand by Type............................. 47 Cht Biocompatible Material Demand by Type, 2005.................... 47 2 Synthetic Biocompatible Polymer Demand by Type................. 50 Cht Synthetic Biocompatible Polymer Demand by Type, 2005.................... 51 3 Biocompatible Thermoplastic Elastomer Demand by Application..... 53 4 Biocompatible Polyvinyl Chloride Demand by Application....... 58 5 Biocompatible Fluoropolymer Demand by Application................... 64 6 Biocompatible Polyurethane Demand by Application................... 68 7 Biocompatible Polycarbonate Demand by Application................... 72 8 Biocompatible Silicone Demand by Application................... 75 9 Biocompatible Acrylic Demand by Application................... 81 10 Biocompatible Thermoplastic Polyester Demand by Application...... 85 11 Biocompatible Polypropylene Demand by Application................... 89 12 Biocompatible Low Density Polyethylenes Demand by Application............................... 93 13 Biocompatible Nylon Demand by Application................... 97 14 Biocompatible Sulfone Resin Demand by Application......... 101 15 Biocompatible High Density Polyethylenes Demand by Application............................. 103 16 Other Synthetic Biocompatible Polymer Demand by Application...... 105 17 Natural Biocompatible Polymer Demand by Type........................... 112 Cht Natural Biocompatible Polymer Demand by Type, 2005.................. 112 18 Biocompatible Cellulose Polymer Demand by Application................. 113 19 Biocompatible Collagen Demand by Application................. 118 20 Biocompatible Starch Blend Demand by Application................. 123 21 Other Natural Biocompatible Polymer Demand by Type Application................... 124 22 Biocompatible Metal Demand by Type........................... 131 Cht Biocompatible Metal Demand by Type, 2005.............................. 131 23 Biocompatible Precious Metal Demand by Application......... 132 24 Biocompatible Stainless Steel Demand by Application.......... 139 25 Biocompatible Titanium Demand by Application................. 143 26 Other Biocompatible Metal Demand by Application................. 144 27 Biocompatible Ceramic Demand by Type Application................... 145 APPLICATIONS 1 Biocompatible Material Demand by Application................. 154 Cht Biocompatible Material Demand by Application, 2005......... 154 2 Biocompatible Material Demand in Surgical Appliances Supplies....... 156 3 Biocompatible Material Demand in Surgical Medical Instruments....... 164 4 Biocompatible Material Demand in Dental Products ........... 165 5 Biocompatible Material Demand in Drug Delivery............... 168 6 Biocompatible Material Demand in Electromedical Equipment.......... 173 7 Biocompatible Material Demand in In Vitro Diagnostic Products........... 175 8 Biocompatible Material Demand in Ophthalmic Goods..................... 177 INDUSTRY STRUCTURE 1 US Biocompatible Material Sales by Company, 2005................ 179 Cht Biocompatible Material Market Share, 2005....................... 181 2 Selected Acquisitions Divestitures................................. 188 3 Selected Cooperative Agreements....... 190
  • 4. Study #2111 September 2006 $4400 264 Pages Biocompatible Materials US Industry Study with Forecasts to 2010 2015 Page Order now, click here! Copyright 2006 The Freedonia Group, Inc. Click here to purchase online US demand to grow 6.6% per year through 2010 Demand for biocompatible materials in the US will increase 6.6 percent annu- ally to $3.7 billion in 2010. Synthetic polymers will continue to record more than half of revenues and post slightly better than average gains in demand. Based on quality and safety advantages in catheters, IV administration sets, IV and blood containers, and orthopedic implants, engineered resins -- especially polycarbonate, thermoplastic elasto- mers, silicone and sulfone compounds -- will provide the best growth opportuni- ties. By contrast, demand for polyvinyl chloride in biocompatible products will expand at a below average pace due to ongoing concerns about DEHP plasti- cizer migration. Hyaluronic acid, collagen to pace natural polymers Increasing use in pharmaceutical excipi- ents, drug delivery systems, cosmetic implants, tissue engineering and wound dressings will boost demand for natural polymers. Hyaluronic acid and collagen will post the strongest gains as new improved bioengineered formulations broaden applications in cosmetic and orthopedic surgery as well as in wound management. Based on well-established performance results, cellulose polymers and starch blends will continue to record substantial gains in pharmaceutical excipients and controlled-release drug delivery systems. Titanium to provide best prospects among metals Precious metals will sustain the largest demand value among biocompatible metals based on high price and wide- spread use in dental repair and restora- tion products. However, reflecting ad- vantages of high strength, low modulus and strong body fluid resistance, titanium and titanium alloys will provide the best growth opportunities. These metals will extend applications in joint replacement systems; dental implants; fusion cages; trauma fixation devices; pacemaker and defibrillator cases; cochlear implant houses; stents; and mechanical heart valves. The penetration of titanium and titanium alloys into new and existing uses will weaken the growth potential of stainless steel and other biocompatible metals, such as cobalt chromium alloys. Ceramics to be fastest growing biocompatibles Ceramics will realize the strongest growth among all biocompatible materi- als as advances in the properties and processing ease of these compounds broaden their uses. New generations of alumina-zirconia nanocomposites are expected to see the strongest gains. These high density structures incorpo- rate greater resistance to cracking, an important advantage in orthopedic im- plants, fixation devices, and dental repair and restoration products. photocourtesyofUSDA Spurred by expanding applications in cosmetic surgery and wound management, hyaluronic acid and collagen will generate the fastest gains in US demand among biocompatible natural polymers. US Biocompatible Materials Demand, 2005 ($2.7 billion) Synthetic Polymers 52% Metals 16% Natural Polymers 22% Ceramics 10%
  • 5. Study #2111 September 2006 $4400 264 Pages Biocompatible Materials US Industry Study with Forecasts to 2010 2015 Page Order now, click here! Click here to purchase online biocompatible materials Synthetic Polymers Synthetic polymers will remain the dominant materials employed in biocompatible products. Total synthetic polymer demand in biocom- patible applications is projected to increase 4.2 percent annually to 695 million pounds, valued at nearly $2 billion, in 2010. These amounts will correspond to nearly 72 percent of the volume and almost 53 percent of the value of biocompatible materials consumed in the US. The leading position of synthetic polymers in various medical, dental pharmaceutical segments reflects ongoing innovations and im- provements in compounds. Technological advances have made available resins that meet the needs of end-use products as to biocompatibility, chemical resistance, infection resistance, clarity, sterilization compat- ibility, processing ease, and overall quality and cost efficiency. All or virtually all medical tubing devices, IV containers and components, syringe cartridges, specimen tubes, and intraocular and contact lenses, as well as a large percentage of dental materials and devices, orthopedic implants, drug delivery systems and wound management supplies, are composed of synthetic polymers. Further improvements and refinements in materials will extend the range of biocompatible products adaptable to commodity and engineered plastic resins. Growth opportunities for synthetic biocompatible polymers will extend into most classes of commodity and engineered resins. Based on cost effectiveness and the availability of improving grades, commodity resins, especially polyvinyl chloride, will continue to dominate low- and medium-value applications in less invasive supplies and devices, such as IV containers and components. Conversely, demand for products with high biocompatibility requirements, including dental and orthope- dic implants, and injectable drug delivery systems, will be met mostly through engineered plastics. Thermoplastic elastomers, fluoropolymers, thermoset polyurethanes, silicone, acrylics and thermoplastic polyesters 48 Sample Text, Table Forecast sample text TABLE III-2 SYNTHETIC BIOCOMPATIBLE POLYMER DEMAND BY TYPE (million dollars) Item 1995 2000 2005 2010 2015 Medical Product Shipments (bil $) 152 245 379 530 735 $ biocomp polymers/000$ shpts 3.98 3.61 3.75 3.72 3.58 Synthetic Biocompatible Polymers 605 885 1420 1970 2630 Thermoplastic Elastomers (TPEs) 72 109 191 285 400 Polyvinyl Chloride (PVC) 90 119 179 223 265 Fluoropolymers 70 103 161 219 290 Polyurethane (PUR) 45 88 149 210 283 Polycarbonate (PC) 59 83 134 205 287 Silicone 50 72 101 150 220 Acrylic 52 71 100 130 166 Thermoplastic Polyesters (TPs) 30 45 77 106 140 Polypropylene (PP) 26 36 66 92 125 Low Density Polyethylene (LDPE) 27 34 55 71 91 Nylon 19 26 41 52 64 Sulfone Resins 12 18 31 46 65 High Density Polyethylene (HDPE) 9 12 21 28 36 Other 44 69 114 153 198 $/lb 1.69 1.92 2.51 2.83 3.09 Synthetic Biocomp Polymers (mil lbs) 358 460 565 695 850 sample table “Demand for low density polyethylenes (including conventional low density, linear low density, ultra low density and metallocene grades) in the production of biocompatible products is projected to increase 3.6 percent annually to 69.8 million pounds, valued at $71 million, in 2010. Fiber applications in bandages, wound dressings and incon- tinence garments will lead gains. In other biocompat- ible products adaptable to LDPEs, such as ...” --Section III, pg. 92 Copyright 2006 The Freedonia Group, Inc.
  • 6. Study #2111 September 2006 $4400 264 Pages Biocompatible Materials US Industry Study with Forecasts to 2010 2015 Page Order now, click here! Click here to purchase online Orthovita Incorporated 45 Great Valley Parkway Malvern, PA 19355 610-640-1775 http://www.orthovita.com Sales: $35 million (2005) US Sales: $32 million (2005) Employment: 140 (2005) Key Products:synthetic, biologically active, tissue engineering products Orthovita is a biomaterials firm. The Company develops, manu- factures and commercializes synthetic, biologically active, tissue engineering products for orthopedic and neurosurgical applications, including bone regeneration. Orthovita’s synthetic, biologically active, tissue engineering products include VITOSS bone graft substitutes, VITOMATRIX par- ticulate synthetic scaffold biomaterials, IMBIBE bone marrow aspirate and delivery devices, VITAGEL composite liquid surgical hemostat, CELLPACKER plasma collection systems, CORTOSS synthetic corti- cal bone, ALIQUOT micro delivery systems and ENDOSKELETON TA vertebral body replacement structural devices. VITOSS bone graft substitute is an ultra-porous resorbable beta-tricalcium phosphate bone void filler material adaptable to a wide range of spinal, dental and orthopedic procedures. VITOMATRIX particulate synthetic scaffold biomaterials, which are based on proprietary beta-tricalcium phosphate biomaterials, are used to make VITOSS bone graft substitutes. IMBIBE bone marrow aspirate and delivery devices from Ortho- vita extract and harvest bone marrow from patients for use in bone 166 COMPANY PROFILES TABLE IV-6 BIOCOMPATIBLE MATERIAL DEMAND IN ELECTROMEDICAL EQUIPMENT (million dollars) Item 1995 2000 2005 2010 2015 Electromedical Equipment Demand 24.0 37.0 61.0 87.0 120.0 Synthetic Polymers: 18.0 27.0 43.0 58.0 76.0 Thermoplastic Elastomers 5.3 9.1 14.4 20.3 28.3 Nylon 5.5 7.4 12.2 15.7 19.0 Acrylic 0.2 0.3 0.5 0.8 1.2 High Density Polyethylene 0.1 0.2 0.4 0.5 0.6 Other 6.9 10.0 15.5 20.7 26.9 Metals: 2.0 3.0 5.0 7.0 9.0 Stainless Steel 1.2 1.8 2.3 2.9 3.6 Titanium 0.2 0.3 1.2 1.6 2.2 Other 0.6 0.9 1.5 2.5 3.2 Ceramics 4.0 7.0 13.0 22.0 35.0 Sample Profile, Table Chart sample profile sample table TABLE V-1 BIOCOMPATIBLE MATERIAL MARKET SHARE, 2005 ($2.7 billion) Market Leaders 31.5% Others 68.5% Dow Chem Georgia G Exxon Mob OxyVinyls BASF DuPont PolyOne Bayer Allegheny GE 1.7% 2.0% 2.4% 2.6% 3.0% 3.1% 3.5% 3.9% 4.1% 5.2% sample chart Copyright 2006 The Freedonia Group, Inc.
  • 7. The Freedonia Group, Inc. 767 Beta Drive • Cleveland, OH • 44143-2326 • USA • Web site: www.freedoniagroup.com Tel US: 800.927.5900 or +1 440.684.9600 • Fax: +1 440.646.0484 • e-mail: info@freedoniagroup.com Order Information Five Convenient Ways to Order Email Title Fax Company Division Street City/State/Zip Country Phone Name (No PO Box please) Signature Order Form Biocompatible Materials............................................. $4400 Additional Print Copies @ $500 each * Total (including selected option) $ Enclosed is my check (5% discount) drawn on a US bank and payable to The Freedonia Group, Inc., in US funds (Ohio residents add 7.75% sales tax) Corporate Use License (add to study price) * +$2300 F-WEB.2111 Signature Signature Page 7 Corporate Use License Now every decision maker in your organization can act on the key intelligence found in all Freedonia studies. For an additional $2300, companies receive unlimited use of an electronic version (PDF) of the study. Place it on your intranet, e-mail it to coworkers around the world, or print it as many times as you like, Click here to learn more about the Corporate Use License Corporate Use License Agreement The above captioned study may be stored on the company’s intranet or shared directory, available to company employees. Copies of the study may be made, but the undersigned represents that distribution of the study will be limited to employees of the company. * Please check appropriate option and sign below to order an electronic version of the study. Individual Use License Agreement The undersigned hereby represents that the above captioned study will be used by only ___ individual(s) who are employees of the company and that the study will not be loaded on a network for multiple users. In the event that usage of the study changes, the Company will promptly notify Freedo- nia of such change and will pay to Freedonia the appropriate fee based on Freedonia’s standard fee schedule then in effect. Note: Entire company cor- porate use license, add $2300; one additional user, add $500; two additional users, add $1000; three additional users, add $1500. Bill my company VisaMasterCardAmerican Express Orders Outside of the US Checks must be made payable in US funds, drawn against a US bank and mailed directly to The Freedonia Group. For wire transfers please contact our customer service department at info@ freedoniagroup.com. Credit cards accepted. ONLINE: www.freedoniagroup.com MAIL: Print out and complete the order form and send to The Freedonia Group (see address at the bottom of this form) PHONE: Call toll free, 800.927.5900 (US) or +1 440.684.9600 FAX: +1 440.646.0484 (US) EMAIL: info@freedoniagroup.com Free Handling Shipping There is NO charge for handling or UPS shipping in the US. Expect delivery in 3 to 5 business days. Outside the US, Freedonia provides free airmail service. Express delivery is available at cost. Save 15% If you order three (3) different titles at the same time, you can receive a 15% discount. If your order is accompanied by a check or wire transfer, you may take a 5% cash discount (discounts do not apply to Corporate Use Licenses). Credit Card Orders For convenience, Freedonia accepts American Ex- press, MasterCard or Visa. Credit card purchases must include account number, expiration date and authorized signature. MM YY Credit Card # Expiration INDUSTRY MARKET RESEARCH FOR BUSINESS LEADERS, STRATEGISTS, DECISION MAKERS
  • 8. About The Freedonia Group The Freedonia Group, Inc., is a leading international industry market research com- pany that provides its clients with information and analysis needed to make informed strategic decisions for their businesses. Studies help clients identify business oppor- tunities, develop strategies, make investment decisions and evaluate opportunities and threats. Freedonia research is designed to deliver unibiased views and reliable outlooks to assist clients in making the right decisions. Freedonia capitalizes on the resources of its proprietary in-house research team of experienced economists, professional analysts, industry researchers and editorial groups. Freedonia covers a diverse group of industries throughout the United States, the emerging China mar- ket, and other world markets. Industries analyzed by Freedonia include: • Chemicals • Plastics • Life Sciences • Packaging • Building Materials • Security Electronics • Industrial Components Equipment • Automotive Transportation Equipment • Household Goods • Energy/Power Equipment The Freedonia Group, Inc. 767 Beta Drive • Cleveland, OH • 44143-2326 • USA • Web site: www.freedoniagroup.com Tel US: 800.927.5900 or +1 440.684.9600 • Fax: +1 440.646.0484 • e-mail: info@freedoniagroup.com Freedonia Custom Research Freedonia Custom Research delivers the same high quality, thorough and unbiased assessment of an industry or market as an industry study. Since the research initia- tive is based upon a company’s specific needs, companies harness Freedonia’s research capabilities and resources to answer unique questions. When you leverage the results of a Freedonia Custom Research engagement, you are able to obtain important answers to specific questions and issues associated with: mergers and acquisitions, new product launches/development, geographic expansion, entry into new markets, strategic business planning, and investment and funding decisions. Freedonia Custom Research is ideal for companies seeking to make a strategic dif- ference in the status quo and focus on future business growth. Working side by side with clients, Freedonia’s team is able to define a research project that is custom-tai- lored to answer specific questions and provide the basis from which a company can make informed business decisions. Click here to learn more about Freedonia Click here to learn more about Custom Research Click here to visit freedoniagroup.com Page 8 Click here for complete title list Other Studies INDUSTRY MARKET RESEARCH FOR BUSINESS LEADERS, STRATEGISTS, DECISION MAKERS Nanotechnology in Health Care US demand for nanotechnology medical products will grow 17.5% annually through 2011, driven by the critical need for new or improved therapies and diag- nostics. The greatest short-term impact will be in can- cer and central nervous system disorders, followed by orthopedic nanoimplants. This study analyzes the $23.6 billion US nanotech medical product industry to 2011, 2016 and 2021 by material, product and appli- cation. The study also reviews product development activities and profiles major players. #2168....................02/2007..................... $4500 Cosmeceuticals US cosmeceuticals demand will grow 8.5% annually, propelled by a stream of new products offering age- defying and other appearance-enhancing benefits. Skin care products will remain dominant while profes- sional products will grow the fastest. BOTOX and hyaluronic acid will lead gains among cosmeceutical chemicals. This study analyzes the $5.4 billion US cosmeceutical industry for 2010 and 2015 by product and chemical. It also evaluates company market share and profiles leading players. #2114....................10/2006..................... $4400 Cosmetic Surgery Products US demand for cosmetic surgery products will grow 9.1% annually through 2010, driven by an obses- sion with youth coupled with an aging population and greater product availability. Nonsurgical markets (e.g., injections, dermal resurfacing, micro-dermabra- sion) will lead gains based on consumer preferences for less invasive treatments. This study analyzes the $1.6 billion US cosmetic surgery product industry to 2010 and 2015 by material, product and procedure. It also evaluates market share and profiles major players. #2099....................09/2006..................... $4300 Natural Polymers US natural polymer demand will grow 5.9% annually through 2010 based on increased food production and opportunities in packaging and medical uses. Starch and fermentation products will grow the fastest and surpass cellulose ethers as the dominant type by 2015. The food and beverage market will remain dominant while medical uses will lead gains. The study analyzes the $2.7 billion US natural polymer industry for 2010 and 2015 by product and market. It also details market share and profiles major players. #2156....................01/2007..................... $4300 Implantable Medical Devices US medical implant demand will rise 9.3% yearly through 2011. Cardiac implants will remain the top- selling group, led by stents and defibrillators. Bone cement, tissue and spinal implants will pace gains in the orthopedic segment. Other fast-growing types in- clude neurological stimulators, cochlear devices and gastric bands. This study analyzes the $27.9 billion US medical implant industry, with forecasts for 2011 and 2016 by material and product. It also evaluates market share and profiles major players. #2255....................10/2007..................... $4500