This document provides a guide for designing and operating high-performance energy efficient buildings in India. It begins with an introduction that establishes the goals and challenges. It then discusses best practices for building design and operation based on case studies and energy modeling. The guide is organized into three sections that cover 1) a whole building framework using lifecycle performance assurance, 2) improving building physical systems like the envelope, lighting, HVAC, and 3) implementing building information systems. The conclusion discusses metrics to evaluate buildings and priorities for best practices. It also explores implications for building codes and policies. The appendices provide a glossary, list of exemplary buildings, technologies, and simulation tools.