Cook science Final NYU Presentation
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The document summarizes the progress and learnings from a 5-day Lean LaunchPad program. It discusses conducting customer interviews with scientists to understand challenges with research reproducibility and finding reliable experimental methods. The team analyzed potential markets and partners, and identified life scientists who struggle to share detailed protocols as their target customer. Going forward, the team will test a prototype website to allow protocol sharing and evaluate how it improves reproducibility.
Cook science Final NYU Presentation
- 1. The ‘Yelp’ of Scientific Protocols CookScience Steve Blank’s 5-Day Lean LaunchPad, NYU Instructors: Steve Blank, Owen Davis, Lindsey Gray, and Frank Rimalovski Team: Fang-Ke Huang, Ph.D. and Jing Deng, Ph.D. Total 53 Type Day One 14 PhD students/Postdoc 38 Day Two 11 Principle Investigators 5 Day Three 11 Business Development 2 Day Four 8 Publishing Editor 2 Day Five 9 Sales & Marketing Manager 6
- 2. CookScience Team Fang-Ke Huang, Ph.D Cancer Biologists Biochemists Postdoctoral Fellow NYU Medical School Jing Deng, Ph.D Immunologist and Virologist Postdoctoral Fellow NYU Medical School
- 3. Impact Factors of research reproducibility CookScience Experimenting Cooking Chemical reagents and Biological Materials Ingredients Protocols Recipes Lab consumables and Lab Equipment Cookware Researchers Cooker
- 4. How to find a reliable methods to plan and implement experiments? Search (Google Scholar, PubMed) Extract protocol Compare Test ☺ yes no Before Protocol Research Article research paper 1 method 1 research paper 1 method 2 method 3 method 4 method 5 method 6 method 7 1hr 1~2 hr 1~2hr 70%-80% Same methods with different variations
- 5. How to find a reliable methods to plan and implement experiments? Search (CookScience Platform) Select (best match, rating, cost, and duration, etc.) Test yes no After 2h Same methods with different variations 1. “Method A for Protein X” contributed by Group Y Researcher Z 20 reviews 10 citations $ 50 48 h 2. “Method A for Protein X” contributed by Group A Researcher B 15 reviews 5 citations $ 40 36 h …… compare
- 6. CookScience Model Canvas ● Our primary customers are life science researchers who cares about research reproducibility but feel frustrated to record detailed lab note; ● Develop and maintain the website and mobile app; ● Help scientists to take detailed lab note; Streamline protocols searching ● Increase research reproducibility; ● Promote lab note sharing. ● Promote methods and experience sharing ● Improve research communication and collaboration ● Reagents supplier; ● Research labs; ● Salary; ● Maintenance fee; ● License fee; ● Hardware cost ● Website; ● mobile app ● Web advertisement; ● Subscription fee; ● Web platform and mobile app developer; ● Customer development team 4 ● self-service with technical support ● Value co-creation with our customers throughout different stages; ● Cost and risk reduction; ● Convenience DAY One: 14
- 7. CookScience Model Canvas ● life science researchers with 4 + year research experience; ● Develop and maintain the website and mobile app; ● Encourage sharing methods and reviews. ● Promote methods and experience sharing; ● Streamline methods searching; ● Increase research reproducibility; ● Improve research communication and collaboration ● Cost and risk reduction; ● Convenience; ● Reagents supplier; ● Research labs; ● Research methods publisher ● Procurement Operation Manager ● University (PhD thesis copyright holder) ● Salary; ● Maintenance fee; ● License fee; ● Hardware cost ● Website; ● mobile app ● Web advertisement; ● Subscription fee; ● Scientific publisher ● Web platform and mobile app developer; ● Customer development team DAY Two: 11 4 ● Value co-creation ● personal assistance and automation ● Reagent suppliers ● Reagents advertisement ● Promote sales ● Automation
- 8. CookScience Model Canvas ● life science researchers with 4 + year research experience, especially cell biologists and immunologists. ● Develop and maintain the website and mobile app; ● Encourage sharing methods and reviews; ● Promote methods and experience sharing; ● Streamline methods searching; ● Increase research reproducibility; ● Improve research communication and collaboration ● Cost and risk reduction; ● Convenience; ● Reagents supplier; ● Research labs; ● Research methods publisher Publisher will not be our partner until our users reach a critical mass. ● Procurement Operation Manager ● University (PhD thesis copyright holder) ● Salary; ● Maintenance fee; ● License fee; ● Hardware cost ● website; ● mobile app ● Web advertisement; ● Subscription fee; ● Scientific publisher ● Web platform and mobile app developer; ● Customer development team DAY Three: 11 4 ● Value co-creation ● personal assistance and automation ● Reagent suppliers ● Reagents advertisement ● Promote sales ● Automation
- 9. CookScience Model Canvas ● life science researchers with 4 + year research experience, especially cell biologists, immunologists, neuroscientists. ● Develop and maintain the website and mobile app; ● Postgraduate PhD students are willing to share their thesis content ● Promote methods and experience sharing; ● Streamline methods searching; ● Increase research reproducibility; ● Improve research communication and collaboration ● Cost and risk reduction; ● Convenience; ● Reagents supplier; ● Research labs; ● Publisher will not be our partner until our users reach a critical mass ● Publisher needs a way to promote their protocols. ● Procurement Operation Manager ● University (PhD thesis copyright holder) ● Salary; ● Maintenance fee; ● License fee; ● Hardware cost ● website; ● mobile app ● Web advertisement; ● Pay per click link; ● Subscription fee; ● Scientific publisher ● Web platform and mobile app developer; ● Customer development team DAY Four: 8 4 ● Value co-creation ● personal assistance and automation ● Reagent suppliers ● Research Service provider ● Reagents advertisement ● Promote sales ● Automation
- 10. Here is what we learned from day 2 to day 4 Customer Segment PhD Student/Postdoc • 27 out of 38 (70%) had a hard time to reproduce a particular experiment, all of them named the lack of detailed protocol as one of the top three reasons. These details include reagent catalog No., lot No., timing, etc. • For those who say they did not experience reproducibility problem, they come from disciplines like, Systems Biology, Organic Chemistry, Structural Biology, Protein Engineering, Nutrition. • For those who say “Yes”, they are cell biologists, neuroscientists, and immunologists. Reagents supplier and their sales channels • One reagent supplier has 70~ 80% of their sales through their websites, especially through search engines. • Some research service providers have their sales through websites as well. • Lab consumable supplier have most of their sales either through direct sales or distributors.
- 11. Total Available Market $ 3.5 B Lab supplies in the world $35 B Percent Cut charged 1% Total Available Market (US) $3.5 B US Share in research output 30% Share of Life Science 50% Share of Reagents and Consumables 50% Served available market (US) $25 M People have issues with existing ways to find methods 50% Target market (US) $25 M Served available market $ 25 M Target market $ 25 M Market Size Trend: expected 3% increase of annual R&D spending in US
- 12. CookScience Publishers science video protocols Social Research Lab management Competitive Landscape
- 13. Potential Partner Publisher • Publisher are not likely to have an interest to partner with us until we have a critical mass of users. • Protocols Publisher does have a need to engage with a lot of scientists to promote their journals. • They even tried to acquire a forum called “Protocol online”.
- 14. CookScience Model Canvas ● life science researchers with 4 + year research experience, especially cell biologists, immunologists, neuroscientists in US. ● Develop and maintain the website and mobile app; ● Postgraduate PhD students are willing to share their thesis content. ● Promote methods and experience sharing; ● Streamline methods searching; ● Increase research reproducibility by providing detailed protocol and anticipated results; ● Improve research communication and collaboration ● Cost and risk reduction; ● Convenience; ● Reagents supplier; ● Research labs; ● Publisher will not be our partner until our users reach a critical mass ● Publisher needs a way to promote their protocols. ● Procurement Operation Manager ● University (PhD thesis copyright holder) ● Salary; ● Maintenance fee; ● License fee; ● Hardware cost ● website; ● mobile app ● Web advertisement; ● Pay per click link; ● Subscription fee; ● Scientific publisher ● Web platform and mobile app developer; ● Customer development team DAY Five: 9 4 ● Value co-creation ● personal assistance and automation ● Reagent suppliers ● Reagents advertisement ● Promote sales ● Automation
- 15. CookScience DAY 5 Customer Segment Here is what we ended Life Scientists - 4+ research experience - cell biologists, immunologists, neuroscientists - US (challenges of sharing protocol internationally) What are the criteria scientists use to choose a particular protocol? - details, catalog no, lot no, temperature, timing - anticipated result (quality of the protocol) - reagents/equipment availability
- 16. What we are going to do next? CookScience • What level of details do scientists prefer? • What kind of format do scientists like? • Given a protocol with balanced details, can it guarantee the reproducibility? If not, how we could measure to what extent it can improve? • How much money and time we could potentially save for scientists? Customer Relationship - Get Strategy • Obtain open access protocols to get started. • Recruit volunteer scientists to rate, review, and comment . • Demo Website Interest: • Offer advertisement for vendors. • Tabling up and visiting number of trade expos • Advertising in various architecture magazine • Blogs, newsletters
- 17. Acknowledgements Steve Blank Teaching Team Owen Davis Frank Rimalovski Lindsey Gray Risa Cohn Jerry Hao Carlo Yuvienco Jasmine Hume Teaching Assistants
- 18. Backup Slides
- 19. CookScience Model Canvas ● Our primary customers are life science researchers who cares about research reproducibility but feel frustrated to record detailed lab note; ● Develop and maintain the website and mobile app; ● Help scientists to take detailed lab note; ● Increase research reproducibility; ● Promote lab note sharing. ● Reagents supplier; ● Research labs; ● Salary; ● Maintenance fee; ● License fee; ● Hardware cost ● Website; ● mobile app ● Web advertisement; ● Subscription fee; ● Web platform and mobile app developer; ● Customer development team DAY 0 4 ● self-service with technical support ● Cost and risk reduction; ● Convenience
- 20. Pivot 1 Hypothesis Value Proposition Scientists struggle to take detailed lab notes Help scientists to take detailed lab note Scientists struggle to find reliable protocols Help scientists to streamline protocols searching