This document discusses methods for measuring emotional response to guide design, including case studies of their application. Preference and desirability testing can provide insights beyond just asking users which option they prefer. Methods discussed include using product reaction cards to assess impressions of brand attributes, quick exposure memory tests, and physiological measurements. Case studies demonstrate applying these methods to redesign a hospital website and refine the design of WestlawNext based on user feedback. The document advocates using both qualitative and quantitative research to inform design decisions.