Explanation slides XL Pedigrees for teaching
- 1. © 2009 NHS National Genetics Education and Development Centre Genetics and Genomics for Healthcare www.geneticseducation.nhs.uk X-Linked Conditions: Case Scenarios This PowerPoint file contains a number of slides that may be useful for teaching of genetics concepts. You may use these slides and their contents for non-commercial educational purposes. This presentation includes: • A Duchenne muscular dystrophy pedigree showing X-linked inheritance • A pedigree used to assess risk of DMD in offspring • A DMD case scenario.
- 2. © 2009 NHS National Genetics Education and Development Centre Genetics and Genomics for Healthcare www.geneticseducation.nhs.uk The X chromosome carrying the disease-causing mutation can be tracked through the family DMD Pedigree
- 3. © 2009 NHS National Genetics Education and Development Centre Genetics and Genomics for Healthcare www.geneticseducation.nhs.uk “Will I have a boy with Duchenne Muscular Dystrophy?”
- 4. © 2009 NHS National Genetics Education and Development Centre Genetics and Genomics for Healthcare www.geneticseducation.nhs.uk Jason’s family tree Jason 15.11.99 Rachel 14.3.74 Tony 26.9.73 Susie 3.6.95 Fay 7.1.98 Jason, aged 3 yrs referred to a paediatrician by his GP •Later walking than older siblings •Difficulty running and riding tricycle •Always climbs up stairs on all fours