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Memory
      Dr. Osama Refaat
Lecturer of Psychiatry, Cairo University
Director of Training Department MOH
Definition
• Memory: The capacity to retain information
  over time
• Memory is one of the most important concepts
  in learning; if things are not remembered, no
  learning can take place
Physiology of Memory
• Memory trace represents a biochemical and
  electrophysiological change in brain
• Major areas:
  – Temporal lobe
  – Diencephalon
  – Mammillary bodies
  – Limbic system (amygdala, hippocampus, cingulate
    gyrus)
• Major neurotransmitters:
  – Acetylcholine
     • Nucleus basalis of Mynert (Forebrain)
  – Glutamate
     • NMDA receptors
Stages of Memory
• Encoding: the conversion of incoming
  information into a form that can be stored in
  memory (memory trace).
• Storage: maintaining information in memory
  over a period of time.
• Retrieval: the process of searching for stored
  information and bringing it to mind.
Basic Reasons for Forgetting
• Encoding Failure: information did not get
  into memory.
• Storage Failure: information has
  disappeared from memory; it is no longer in
  storage.
• Retrieval Failure: information is stored in
  memory but it cannot be located.
Major Theories of Forgetting
• Decay Theory: information in memory
  eventually disappears if it is not used. (“Use it
  or lose it.”)
• Interference Theory: information stays in
  memory permanently even if it is not used.
  Forgetting occurs because other things we have
  learned somehow prevent us from finding the
  information we want
• Repression: active forgetfulness
Experiment
You learn a list of 10 “nonsense
 syllables” (like XUG or MUW),
 then get a test on it 1, 2, 4 or 8
 hours later (“retention interval”).
 Does it matter if you are asleep
 or awake during this retention
 interval?
We are exposed to new information when we are
  awake but not when we are asleep.
  Compare the amount recalled after 8
  hours awake to the amount recalled after
  8 hours asleep.
  Your choices:
   (A) Recall will be higher after being asleep.
   (B) Recall will be higher after being awake.
   (C) Asleep = awake.
Decay Theory predicts: ?
Interference Theory predicts: ?
Decay Theory predicts: C

Interference Theory predicts: A
Results Supported the
Syllables Recalled (out of 10)

                                 10
                                          Interference Theory


                                                     Asleep
                                 5



                                                      Awake
                                 0




                                      0   2           4        6   8
                                              Retention Interval
Types of Memory

3 types of memories:
 – Sensory Memory
 – Short-Term Memory
 – Long-Term Memory
These memories differ in terms of
 3 characteristics:
• Capacity:      how many units of
 information can be held at one time.
• Duration of Storage:               how long
 the information can be held.
• Reason for Forgetting:                storage
 failure versus retrieval failure.
Long-Term Memory
• Relatively permanent storage of
  information
Long-Term Memory Contains...



  Declarative Memory:               Nondeclarative Memory:
                                       Information you cannot
  Information you can describe
                                              describe




Semantic              Episodic
                      Memory:         Skilled
Memory:                                                  Habits
                       Personally     actions
  General
                      experienced
information
                         events
Long-Term Memory

• Capacity: virtually unlimited.
• Duration of Storage: up to         a
 lifetime.
• Reason for forgetting:         retrieval
 failure (e.g., interference).
Short-Term Memory
          (Working Memory)
• Def: Brief storage of information
  currently being used
• Capacity:        7 units, plus or minus 2
  – Chunking can increase the capacity of STM
• Duration of Storage:                 less than 30
 seconds without rehearsal.
• Reason for forgetting:                storage failure
 (e.g., decay, displacement).
Sensory Memory
• Def: Temporary storage of
  information
• Capacity:         large; contains most
    details of sensory input.
•   Duration of Storage: visual:
    1/10 second; auditory: 2 seconds.
•   Reason for forgetting: storage
    failure (e.g., decay).
Forgetting
STM             LTM


 Forgetting from Short-Term Memory:
       Decay or Displacement?

After information enters STM, a copy may or may
not be sent to LTM.
Soon, however, that information will disappear
from STM.

Two processes could cause information to
disappear from STM: decay and displacement.
STM            LTM


 Forgetting from Short-Term Memory:
       Decay or Displacement?

Decay: information that is not rehearsed disappears
as time passes.

Displacement: information being held in STM is
pushed out by newly arriving information.

Displacement is most likely to occur when the
capacity limit of STM has been reached (about 7
units of information).
STM            LTM


 Forgetting from Short-Term Memory:
       Decay or Displacement?



B        R      D      Q      L     T     H       J




Displacement is most likely to occur when the
capacity limit of STM has been reached (about 7
units of information).
STM            LTM


 Forgetting from Short-Term Memory:
       Decay or Displacement?



         B      R      D      Q     L     T       H




                                                  J
Displacement is most likely to occur when the
capacity limit of STM has been reached (about 7
units of information).
Types of Interference
• Retroactive Interference:
  – Recently learned information prevents recall of
    earlier learned information.
• Proactive Interference:
  – Earlier learned information prevents recall of later
    learned information
• When information is learnt:
• RI:
                                Interferin
  Target Info                     g Info

• PI:

    Interferin
      g Info                    Target Info
• When information is learnt:
• RI:

   Lesson 1                     Lesson 2


• PI:

        Lesson 1                 Lesson 2
Remembering
Basic Sequence

Sensory                        Short-Term         Long-Term
           Sensory Memory
Input                          Memory             Memory


    Suppose that you wanted to memorize the phone
    number of a restaurant: 562-7837. In terms of the
    model, your goal is to get this information into long-
    term memory.
    You look at a page of a phone book.
    Scanning the page, you find the listing you want.
    This is a “sensory input” to the system. The first stop
    is sensory memory.
Basic Sequence

Sensory                         Short-Term      Long-Term
           Sensory Memory
Input                           Memory          Memory
                        Attention

    A copy is made in sensory memory of the visual
    patterns, 562-7837.
    Generally, just paying attention to something in
    sensory memory moves it to short-term memory.
    However, with verbal information, there is an extra
    step because short-term memory prefers to take
    information in an auditory form—a form you can hear.
Basic Sequence

Sensory                         Short-Term       Long-Term
           Sensory Memory
Input                           Memory           Memory
                        Attention

    This is called auditory encoding, the conversion of
    visual patterns to sounds. You do this when you
    “listen” to the sounds of these words on the screen.
    It involves pattern recognition. Visual patterns in
    sensory memory are compared to prototypes in long-
    term memory.
Basic Sequence

Sensory                             Short-Term             Long-Term
             Sensory Memory
Input                               Memory                 Memory
                           Attention

    Sounds corresponding to the visual patterns are then
    located and copied into short-term memory.      .

    When you become aware of these sounds, you know
    they are in short-term memory. The process of
    auditory encoding has been completed.
    The link from LTM to STM illustrates the process of retrieval, a
    key intermediate step in memorization.
Basic Sequence

Sensory                         Short-Term     Long-Term
           Sensory Memory
Input                           Memory         Memory
                        Attention

    You have a new sequence of sounds in short-term
    memory: 562-7837. Your goal is to move this
    sequence into long-term memory.

    There are two strategies for moving information from
    STM to LTM: (1) repetition; (2) elaboration.
Basic Sequence

Sensory                         Short-Term           Long-Term
           Sensory Memory
Input                           Memory               Memory
                        Attention            Repetition

    When you repeat (rehearse) information, two things
    happen:
    1. You recirculate it in STM. Each time you do this,
    you “reset the clock” and get another few seconds
    before the information decays.
    2. You increase the chances that the information will
    be copied into LTM. But this is an unreliable strategy.
Basic Sequence

Sensory                         Short-Term           Long-Term
           Sensory Memory
Input                           Memory               Memory
                        Attention            Elaboration

    Elaboration is much more effective. You retrieve
    related information from LTM and combine it with the
    information you are holding in STM.

    For example, you can use the letters that correspond
    to the digits on the phone dial and make a word out of
    the digits:
Basic Sequence

Sensory                           Short-Term           Long-Term
             Sensory Memory
Input                             Memory               Memory
                          Attention            Elaboration

                   5 6 2 - 7 8 3 7

                   L O B          S T E R

          Visualization works best. Try to come up with
          words that refer to objects you can picture in
          your “mind’s eye”.
Basic Sequence

Sensory                         Short-Term           Long-Term
           Sensory Memory
Input                           Memory               Memory
                        Attention            Elaboration

      What you encode (enter into) long-term memory
      is the word, lobster, and the mental picture of a
      lobster. You also encode the rule, “Dial the digits
      that go with the letters.”
Basic Sequence

Sensory                         Short-Term           Long-Term
           Sensory Memory
Input                           Memory               Memory
                        Attention            Elaboration

      It will help if you create a mental picture that
      links the lobster to the restaurant; maybe visualize
      a lobster going inside, like a customer.
      When it comes time to dial, the thought of the
      restaurant triggers the image of the lobster, which
      reminds you of your code word, “lobster”, and the
      rule: “Dial the digits that go with the letters.”
Testing Memory
• Bed side tests
  – Registration
  – Short term memory (digit span: the capacity to hear
    and immediately repeat back a unfamiliar sequence
    of numbers)
  – Long term memory
• Specialized memory tests
  – WMS
• Part of cognitive battery
  – CAMCOG
Disorders of Memory
• Amnesia:
  –   Anterograde
  –   Retrograde
  –   Global
  –   Circumscribed
• Hypermnesia
• Paramnesia:
  –   Retrospective Falsification
  –   Confabulation
  –   Déjà vu (illusion of familiarity)
  –   Jamais vu (illusion of unfamiliarity)
Final memory

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Final memory

  • 1. Memory Dr. Osama Refaat Lecturer of Psychiatry, Cairo University Director of Training Department MOH
  • 2. Definition • Memory: The capacity to retain information over time • Memory is one of the most important concepts in learning; if things are not remembered, no learning can take place
  • 3. Physiology of Memory • Memory trace represents a biochemical and electrophysiological change in brain • Major areas: – Temporal lobe – Diencephalon – Mammillary bodies – Limbic system (amygdala, hippocampus, cingulate gyrus)
  • 4. • Major neurotransmitters: – Acetylcholine • Nucleus basalis of Mynert (Forebrain) – Glutamate • NMDA receptors
  • 5. Stages of Memory • Encoding: the conversion of incoming information into a form that can be stored in memory (memory trace). • Storage: maintaining information in memory over a period of time. • Retrieval: the process of searching for stored information and bringing it to mind.
  • 6. Basic Reasons for Forgetting • Encoding Failure: information did not get into memory. • Storage Failure: information has disappeared from memory; it is no longer in storage. • Retrieval Failure: information is stored in memory but it cannot be located.
  • 7. Major Theories of Forgetting • Decay Theory: information in memory eventually disappears if it is not used. (“Use it or lose it.”) • Interference Theory: information stays in memory permanently even if it is not used. Forgetting occurs because other things we have learned somehow prevent us from finding the information we want • Repression: active forgetfulness
  • 8. Experiment You learn a list of 10 “nonsense syllables” (like XUG or MUW), then get a test on it 1, 2, 4 or 8 hours later (“retention interval”). Does it matter if you are asleep or awake during this retention interval?
  • 9. We are exposed to new information when we are awake but not when we are asleep. Compare the amount recalled after 8 hours awake to the amount recalled after 8 hours asleep. Your choices: (A) Recall will be higher after being asleep. (B) Recall will be higher after being awake. (C) Asleep = awake. Decay Theory predicts: ? Interference Theory predicts: ?
  • 10. Decay Theory predicts: C Interference Theory predicts: A
  • 11. Results Supported the Syllables Recalled (out of 10) 10 Interference Theory Asleep 5 Awake 0 0 2 4 6 8 Retention Interval
  • 12. Types of Memory 3 types of memories: – Sensory Memory – Short-Term Memory – Long-Term Memory
  • 13. These memories differ in terms of 3 characteristics: • Capacity: how many units of information can be held at one time. • Duration of Storage: how long the information can be held. • Reason for Forgetting: storage failure versus retrieval failure.
  • 14. Long-Term Memory • Relatively permanent storage of information
  • 15. Long-Term Memory Contains... Declarative Memory: Nondeclarative Memory: Information you cannot Information you can describe describe Semantic Episodic Memory: Skilled Memory: Habits Personally actions General experienced information events
  • 16. Long-Term Memory • Capacity: virtually unlimited. • Duration of Storage: up to a lifetime. • Reason for forgetting: retrieval failure (e.g., interference).
  • 17. Short-Term Memory (Working Memory) • Def: Brief storage of information currently being used • Capacity: 7 units, plus or minus 2 – Chunking can increase the capacity of STM • Duration of Storage: less than 30 seconds without rehearsal. • Reason for forgetting: storage failure (e.g., decay, displacement).
  • 18. Sensory Memory • Def: Temporary storage of information • Capacity: large; contains most details of sensory input. • Duration of Storage: visual: 1/10 second; auditory: 2 seconds. • Reason for forgetting: storage failure (e.g., decay).
  • 20. STM LTM Forgetting from Short-Term Memory: Decay or Displacement? After information enters STM, a copy may or may not be sent to LTM. Soon, however, that information will disappear from STM. Two processes could cause information to disappear from STM: decay and displacement.
  • 21. STM LTM Forgetting from Short-Term Memory: Decay or Displacement? Decay: information that is not rehearsed disappears as time passes. Displacement: information being held in STM is pushed out by newly arriving information. Displacement is most likely to occur when the capacity limit of STM has been reached (about 7 units of information).
  • 22. STM LTM Forgetting from Short-Term Memory: Decay or Displacement? B R D Q L T H J Displacement is most likely to occur when the capacity limit of STM has been reached (about 7 units of information).
  • 23. STM LTM Forgetting from Short-Term Memory: Decay or Displacement? B R D Q L T H J Displacement is most likely to occur when the capacity limit of STM has been reached (about 7 units of information).
  • 24. Types of Interference • Retroactive Interference: – Recently learned information prevents recall of earlier learned information. • Proactive Interference: – Earlier learned information prevents recall of later learned information
  • 25. • When information is learnt: • RI: Interferin Target Info g Info • PI: Interferin g Info Target Info
  • 26. • When information is learnt: • RI: Lesson 1 Lesson 2 • PI: Lesson 1 Lesson 2
  • 28. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Suppose that you wanted to memorize the phone number of a restaurant: 562-7837. In terms of the model, your goal is to get this information into long- term memory. You look at a page of a phone book. Scanning the page, you find the listing you want. This is a “sensory input” to the system. The first stop is sensory memory.
  • 29. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention A copy is made in sensory memory of the visual patterns, 562-7837. Generally, just paying attention to something in sensory memory moves it to short-term memory. However, with verbal information, there is an extra step because short-term memory prefers to take information in an auditory form—a form you can hear.
  • 30. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention This is called auditory encoding, the conversion of visual patterns to sounds. You do this when you “listen” to the sounds of these words on the screen. It involves pattern recognition. Visual patterns in sensory memory are compared to prototypes in long- term memory.
  • 31. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention Sounds corresponding to the visual patterns are then located and copied into short-term memory. . When you become aware of these sounds, you know they are in short-term memory. The process of auditory encoding has been completed. The link from LTM to STM illustrates the process of retrieval, a key intermediate step in memorization.
  • 32. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention You have a new sequence of sounds in short-term memory: 562-7837. Your goal is to move this sequence into long-term memory. There are two strategies for moving information from STM to LTM: (1) repetition; (2) elaboration.
  • 33. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention Repetition When you repeat (rehearse) information, two things happen: 1. You recirculate it in STM. Each time you do this, you “reset the clock” and get another few seconds before the information decays. 2. You increase the chances that the information will be copied into LTM. But this is an unreliable strategy.
  • 34. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention Elaboration Elaboration is much more effective. You retrieve related information from LTM and combine it with the information you are holding in STM. For example, you can use the letters that correspond to the digits on the phone dial and make a word out of the digits:
  • 35. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention Elaboration 5 6 2 - 7 8 3 7 L O B S T E R Visualization works best. Try to come up with words that refer to objects you can picture in your “mind’s eye”.
  • 36. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention Elaboration What you encode (enter into) long-term memory is the word, lobster, and the mental picture of a lobster. You also encode the rule, “Dial the digits that go with the letters.”
  • 37. Basic Sequence Sensory Short-Term Long-Term Sensory Memory Input Memory Memory Attention Elaboration It will help if you create a mental picture that links the lobster to the restaurant; maybe visualize a lobster going inside, like a customer. When it comes time to dial, the thought of the restaurant triggers the image of the lobster, which reminds you of your code word, “lobster”, and the rule: “Dial the digits that go with the letters.”
  • 38. Testing Memory • Bed side tests – Registration – Short term memory (digit span: the capacity to hear and immediately repeat back a unfamiliar sequence of numbers) – Long term memory • Specialized memory tests – WMS • Part of cognitive battery – CAMCOG
  • 39. Disorders of Memory • Amnesia: – Anterograde – Retrograde – Global – Circumscribed • Hypermnesia • Paramnesia: – Retrospective Falsification – Confabulation – Déjà vu (illusion of familiarity) – Jamais vu (illusion of unfamiliarity)