The document describes using membrane computing models to find nearly-optimal solutions to cost-based abduction problems. Membrane computing models problems using hierarchical membrane structures containing objects that evolve through rules. The problem of cost-based abduction is to find the lowest-cost proof for a goal given hypotheses with assumability costs. The approach models candidate solutions as strings within membranes and uses repair, breeding, and feedback rules to evolve better solutions over time. Experimental results suggest membrane computing can find low-cost solutions to cost-based abduction problems.