The document discusses the importance of layout and design in human-computer interaction. It emphasizes establishing a clear structure or hierarchy with key elements like a title, introduction, content sections, illustrations and navigation. The structure should group related elements closer together. It also stresses the importance of consistency in layout, such as choosing a basic composition like central, left-aligned, etc. and following basic rules like putting important elements at the top, using white space, minimizing clutter, and adding visual contrast.